Search Results - "Motloch, Lukas J"
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Implementation of risk-based lipid-lowering therapies in older (age ≥ 65 years) and very-old adults (age ≥ 75 years) with ischemic heart disease in the greater Salzburg region
Published in Frontiers in pharmacology (19-06-2024)“…European guidelines recommend the implementation of lipid-lowering therapies (LLTs) in adults (≥ 65 years) with established atherosclerotic cardiovascular…”
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The Classically Cardioprotective Agent Diazoxide Elicits Arrhythmias in Type 2 Diabetes Mellitus
Published in Journal of the American College of Cardiology (08-09-2015)“…Abstract Background Type 2 diabetes mellitus (T2DM) is associated with an enhanced propensity for ventricular tachyarrhythmias (VTs) under conditions of…”
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Impella use in real-world cardiogenic shock patients: Sobering outcomes
Published in PloS one (26-02-2021)“…Critically ill patients with cardiogenic shock could benefit from ventricular assist device support using the Impella microaxial blood pump. However, recent…”
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J-waves in acute COVID-19: A novel disease characteristic and predictor of mortality?
Published in PloS one (14-10-2021)“…Background J-waves represent a common finding in routine ECGs (5–6%) and are closely linked to ventricular tachycardias. While arrhythmias and non-specific ECG…”
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Clinical impact of atrial fibrillation in patients with pulmonary hypertension
Published in PloS one (16-03-2012)“…Pulmonary hypertension (PH) is associated with progressive impairment of right ventricular function, reduced exercise capacity and a poor prognosis. Little is…”
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Long-Term Outcomes of COVID-19 in Hospitalized Type 2 Diabetes Mellitus Patients
Published in Biomedicines (01-02-2024)“…With the onset of the coronavirus pandemic, it has become clear that patients with diabetes are at risk for more severe and fatal COVID-19. Type 2 diabetes…”
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Hypertrophic cardiomyopathy is characterized by alterations of the mitochondrial calcium uniporter complex proteins: insights from patients with aortic valve stenosis versus hypertrophic obstructive cardiomyopathy
Published in Frontiers in pharmacology (22-11-2023)“…Hypertrophies of the cardiac septum are caused either by aortic valve stenosis (AVS) or by congenital hypertrophic obstructive cardiomyopathy (HOCM). As they…”
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Pathophysiology of Calcium Mediated Ventricular Arrhythmias and Novel Therapeutic Options with Focus on Gene Therapy
Published in International journal of molecular sciences (24-10-2019)“…Cardiac arrhythmias constitute a major health problem with a huge impact on mortality rates and health care costs. Despite ongoing research efforts, the…”
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Subcutaneous administration of levothyroxine: a novel approach to refractory hypothyroidism - A review and a case report
Published in Archives of Endocrinology and Metabolism (29-10-2021)“…Treatment-refractory hypothyroidism is a common clinical finding. Substantial causes include poor compliance and intake failure as well as gastrointestinal…”
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Connexin 43 acts as a cytoprotective mediator of signal transduction by stimulating mitochondrial KATP channels in mouse cardiomyocytes
Published in The Journal of clinical investigation (03-05-2010)“…Potassium (K+) channels in the inner mitochondrial membrane influence cell function and survival. Increasing evidence indicates that multiple signaling…”
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Prophylactic rivaroxaban in the early post-discharge period reduces the rates of hospitalization for atrial fibrillation and incidence of sudden cardiac death during long-term follow-up in hospitalized COVID-19 survivors
Published in Frontiers in pharmacology (30-05-2023)“…While acute Coronavirus disease 2019 (COVID-19) affects the cardiovascular (CV) system according to recent data, an increased CV risk has been reported also…”
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Investigation of hs-TnI and sST-2 as Potential Predictors of Long-Term Cardiovascular Risk in Patients with Survived Hospitalization for COVID-19 Pneumonia
Published in Biomedicines (01-11-2022)“…Introduction: COVID-19 survivors reveal an increased long-term risk for cardiovascular disease. Biomarkers like troponins and sST-2 improve stratification of…”
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Myocardial injury in severe COVID‐19 is similar to pneumonias of other origin: results from a multicentre study
Published in ESC Heart Failure (01-02-2021)“…Aims COVID‐19, a respiratory viral disease causing severe pneumonia, also affects the heart and other organs. Whether its cardiac involvement is a specific…”
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The Diagnostic and Therapeutic Value of Multimarker Analysis in Heart Failure. An Approach to Biomarker-Targeted Therapy
Published in Frontiers in cardiovascular medicine (04-12-2020)“…Heart failure is a pathophysiological state, which is still associated with high morbidity and mortality despite established therapies. Diverse well-known…”
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Case report: Short-long-short mechanism triggering sustained ventricular tachycardia in a patient with a single-chamber ICD but inhibiting antitachycardia therapy
Published in Frontiers in cardiovascular medicine (26-08-2022)“…Introduction Short-long-short (SLS) sequences are an important cause of ICD pro-arrhythmia and can initiate both polymorphic and monomorphic ventricular…”
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Postprocedural Atrial Fibrillation After Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement
Published in The Annals of thoracic surgery (2012)“…Background Transcatheter aortic valve implantation (TAVI) represents an alternative option for elderly patients with severe aortic valve stenosis who are…”
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Cardiovascular Biomarkers for Prediction of in-hospital and 1-Year Post-discharge Mortality in Patients With COVID-19 Pneumonia
Published in Frontiers in medicine (28-06-2022)“…Aims While COVID-19 affects the cardiovascular system, the potential clinical impact of cardiovascular biomarkers on predicting outcomes in COVID-19 patients…”
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A Comparative Analysis of Novel Biomarkers in Sepsis and Cardiovascular Disease
Published in Applied sciences (01-02-2022)“…(1) Background: Sepsis still represents a major health care challenge, with mortality rates exceeding 25% in the western world. To further improve outcomes in…”
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Dexamethasone Improves Cardiovascular Outcomes in Critically Ill COVID-19, a Real World Scenario Multicenter Analysis
Published in Frontiers in medicine (02-02-2022)“…Severe COVID-19 pneumonia requiring intensive care treatment remains a clinical challenge to date. Dexamethasone was reported as a promising treatment option,…”
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Analysis of Selected Cardiovascular Biomarkers in Takotsubo Cardiomyopathy and the Most Frequent Cardiomyopathies
Published in Frontiers in cardiovascular medicine (03-11-2021)“…Introduction: Among the causes of de novo diagnosed cardiomyopathy, Takotsubo cardiomyopathy (TTC) plays a minor role, with an occurrence of 50,000–100,000…”
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