Search Results - "Motlı́k, J"

Prophase I arrest and progression to metaphase I in mouse oocytes: comparison of resumption of meiosis and recovery from G2-arrest in somatic cells by Solc, Petr, Schultz, Richard M., Motlik, Jan

“…Mammalian oocytes are arrested at prophase I until puberty when luteinizing hormone (LH) induces resumption of meiosis of follicle-enclosed oocytes. Resumption…”
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In vitro and in vivo evaluation of genetically corrected RPE cells for autologous cell therapy of hereditary retinal dystrophies by Rodriguez‐Jimenez, F. J., Brymova, A., Mueller, B., Stieger, K., Jendelova, P., Ardan, T., Studenovská, H., Lytvynchuk, L., Straňák, Z., Ellederová, Z., Juhás, J., Motlík, J., Petrovski, G., Erceg, Lukovic D.

“…Purpose: The generation of genetically corrected RPE cells from patient‐derived human induced pluripotent stem cells (hiPSCs) may provide a source for…”
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Transduction profiles in minipig following MRI guided delivery of AAV-5 into thalamic and corona radiata areas by Pietersz, K.L., Pouw, S., Klima, J., Ellederova, Z., Bohuslavova, B., Chrastina, J., Liscak, R., Urgosik, D., Starek, Z., Crha, M., Lewis, O., Wooley, M., Johnson, D., Brouwers, C.C., Evers, M., Motlik, J., Martens, G.J.M., Konstantinova, P.S., Blits, B.

“…As a step towards clinical use of AAV-mediated gene therapy, brains of large animals are used to settle delivery parameters as most brain connections, and…”
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Comparing over-the-scope clip versus endoloop and clips (KING closure) for access site closure: a randomized experimental study by Martínek, J., Ryska, O., Tuckova, I., Filípková, T., Doležel, R., Juhas, S., Motlík, J., Zavoral, M., Ryska, M.

“…Background A safe technique is essential for successful access site closure in Natural Orifice Translumenal Endoscopic Surgery (NOTES) and for closures of…”
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Upregulated expression of proteolytic enzymes in the cultured retinal pigment epithelial cells of minipig transgenic for the human mutated huntingtin by Ardan, T., Kocurova, G., Hrnciarova, E., Motlik, J.

“…Purpose Huntington′s disease (HD) belongs to the hereditary neurodegenerative disorder that is caused by an expansion of a polyglutamine (polyQ) domain in the…”
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Porcine epidermal stem cells as a biomedical model for wound healing and normal/malignant epithelial cell propagation by Motlík, J., Klíma, J., Dvořánková, B., Smetana, K.

“…This article summarizes research using cells derived from epidermis of the miniature pigs for use as a cell therapy for skin repair and as a model for squamous…”
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Nanofibrous carrier for transplantation of retinal pigment epithelial cells by Ardan, T., Popelka, Š., Straňák, Z., Kozak, I., Lytvynchuk, L., Rais, D., Dušková, M., Motlík, J.

“…Summary The most common retinal degenerative diseases such as age‐related macular degeneration (AMD) and retinitis pigmentosa belong to serious eye diseases…”
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Osteogenic differentiation of miniature pig mesenchymal stem cells in 2D and 3D environment by Juhásová, J, Juhás, S, Klíma, J, Strnádel, J, Holubová, M, Motlík, J

“…Mesenchymal stem cells (MSCs) have been repeatedly shown to be able to repair bone defects. The aim of this study was to characterize the osteogenic…”
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Cell cycle synchronization of porcine fetal fibroblasts: effects of serum deprivation and reversible cell cycle inhibitors by Kues, W.A, Anger, M, Carnwath, J.W, Paul, D, Motlik, J, Niemann, H

“…The success of somatic nuclear transfer critically depends on the cell cycle stage of the donor nucleus and the recipient cytoplast. In this study we tested…”
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Time Course of Spinal Doublecortin Expression in Developing Rat and Porcine Spinal Cord: Implication in In Vivo Neural Precursor Grafting Studies by Juhasova, J., Juhas, S., Hruska-Plochan, M., Dolezalova, D., Holubova, M., Strnadel, J., Marsala, S., Motlik, J., Marsala, M.

“…Expression of doublecortin (DCX), a 43–53 kDa microtubule binding protein, is frequently used as (i) an early neuronal marker to identify the stage of neuronal…”
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Differential regulation of galectin expression/reactivity during wound healing in porcine skin and in cultures of epidermal cells with functional impact on migration by Klíma, J, Lacina, L, Dvořánková, B, Herrmann, D, Carnwath, J W, Niemann, H, Kaltner, H, André, S, Motlík, J, Gabius, H-J, Smetana, Jr, K

“…The glycophenotyping of mammalian cells with plant lectins maps aspects of the glycomic profile and disease-associated alterations. A salient step toward…”
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Survival and differentiation of human embryonic stem cell-derived neural precursors grafted spinally in spinal ischemia-injured rats or in naive immunosuppressed minipigs: a qualitative and quantitative study by Kakinohana, O, Juhasova, J, Juhas, S, Motlik, J, Platoshyn, O, Galik, J, Hefferan, M, Yuan, S H, Vidal, J G, Carson, C T, van Gorp, S, Goldberg, D, Leerink, M, Lazar, P, Marsala, S, Miyanohara, A, Keshavarzi, S, Ciacci, J D, Marsala, M

“…In previous studies, we have demonstrated that spinal grafting of human or rat fetal spinal neural precursors leads to amelioration of spasticity and…”
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B33 Non-neural Mitochondrial Impairment In Huntington’s Disease Patients And Minipigs Transgenic For The N-terminal Part Of Human Mutated Huntingtin by Hansíková, H, Rodinová, M, Spáčilová, J, Kratochvílová, H, Sládková, J, Marková, M, Mačáková, M, Bohuslavová, B, Ellederová, Z, Juhasová, J, Lišková, I, Klempir, J, Roth, J, Motlik, J, Zeman, J

“…The most pathological effects of Huntington’s disease (HD) are focused on the central nervous system but numerous reports had described abnormalities in…”
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Mammalian oocyte activation: lessons from the sperm and implications for nuclear transfer by Alberio, R, Zakhartchenko, V, Motlik, J, Wolf, E

“…Events after fertilisation have been carefully studied in the last decades. However, there are still several questions to be clarified in relation to the…”
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Butyrolactone I reversibly inhibits meiotic maturation of bovine oocytes, without influencing chromosome condensation activity by Kubelka, M, Motlik, J, Schultz, R.M, Pavlok, A

“…In this study, butyrolactone I (BL I), a potent and specific inhibitor of cyclin-dependent kinases, was shown to block germinal vesicle (GV) breakdown (GVBD)…”
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Interplay between CDC2 kinase and MAP kinase pathway during maturation of mammalian oocytes by Motlik, J., Pavlok, A., Kubelka, M., Kalous, J., Kalab, P.

“…Two principal kinases, p34 cdc2 kinase and MAP kinase play a pivotal role in maturation of mammalian oocytes. In the porcine and bovine oocytes both kinases…”
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Composite hyaluronate-type I collagen-fibrin scaffold in the therapy of osteochondral defects in miniature pigs by Filová, E, Rampichová, M, Handl, M, Lytvynets, A, Halouzka, R, Usvald, D, Hlucilová, J, Procházka, R, Dezortová, M, Rolencová, E, Kostáková, E, Trc, T, Stastný, E, Kolácná, L, Hájek, M, Motlík, J, Amler, E

“…The potential of novel scaffold containing sodium hyaluronate, type I collagen, and fibrin was investigated in the regeneration of osteochondral defects in…”
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Culture of bovine oocytes from small antral follicles in meiosis-inhibiting medium with butyrolactone I: RNA synthesis, nucleolar morphology and meiotic competence by Pavlok, A, Kaňka, J, Motlı́k, J, Vodička, P

“…Bovine oocytes originated from follicles of two different size categories (medium (M), 3–6mm and small (S), 1–2mm) were cultured for 24 and 70h, respectively,…”
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Impact of Two-step in vitro Culture Systems on Developmental Potency of Oocytes by Motlík, J, Pavlok, A, Lapathitis, G, Kubelka, M

“…Contents Proper conditions for the successful induction of a functional two step in vitro culture system for agricultural or clinical applications are hereby…”
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Permanent jugular catheterization in miniature pig: treatment, clinical and pathological observatio by Usvald, D., Hlucilova, J., Strnadel, J., Prochazka, R., Motlik, J., Marsala, M.

“…The aim of present study was the installation of permanent jugular catheter to miniature pigs, which are frequently used as animal model for the experiments…”
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