Search Results - "Motala, Zainab"

Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma by Hayes, Madeline N., McCarthy, Karin, Jin, Alexander, Oliveira, Mariana L., Iyer, Sowmya, Garcia, Sara P., Sindiri, Sivasish, Gryder, Berkley, Motala, Zainab, Nielsen, G. Petur, Borg, Jean-Paul, van de Rijn, Matt, Malkin, David, Khan, Javed, Ignatius, Myron S., Langenau, David M.

“…Tumor growth and relapse are driven by tumor propagating cells (TPCs). However, mechanisms regulating TPC fate choices, maintenance, and self-renewal are not…”
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The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma by Ignatius, Myron S., Hayes, Madeline N., Lobbardi, Riadh, Chen, Eleanor Y., McCarthy, Karin M., Sreenivas, Prethish, Motala, Zainab, Durbin, Adam D., Molodtsov, Aleksey, Reeder, Sophia, Jin, Alexander, Sindiri, Sivasish, Beleyea, Brian C., Bhere, Deepak, Alexander, Matthew S., Shah, Khalid, Keller, Charles, Linardic, Corinne M., Nielsen, Petur G., Malkin, David, Khan, Javed, Langenau, David M.

“…Tumor-propagating cells (TPCs) share self-renewal properties with normal stem cells and drive continued tumor growth. However, mechanisms regulating…”
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Abstract 2741: Assessing the utility of circulating tumor DNA as a surveillance tool for sarcomas and Li-Fraumeni syndrome using a pre-clinical model by Paramathas, Sangeetha, Lewis, Nathan, Guha, Tanya, Motala, Zainab, Malkin, David

“…Li-Fraumeni Syndrome (LFS) is a hereditary cancer predisposition syndrome commonly characterized by the presence of inherited mutations in the tumor suppressor…”
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Abstract 5029: The role of estrogen receptor signaling in rhabdomyosarcoma by Motala, Zainab A., Chen, Kevin, Malkin, David

“…Rhabdomyosarcoma (RMS) is a malignant tumor thought to arise from immature precursors of skeletal muscle cells. In children, RMS accounts for approximately 50%…”
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Efficacy of Tamoxifen, Alone or in Combination with Vincristine and Temsirolimus, in in vitro and in vivo Models of Rhabdomyosarcoma by Motala, Zainab

“…Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood, with an estimated five-year overall survival of less than 30% in patients with…”
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Abstract 3171: Vangl2 regulates cancer stem cell self-renewal and growth in rhabdomyosarcoma by Hayes, Madeline, McCarthy, Karin, Jin, Alexander, Iyer, Sowmya, Garcia, Sara, Oliveira, Mariana L., Sindiri, Sivasish, Gryder, Berkley, Motala, Zainab, Nielsen, G Petur, Borg, Jean-Paul, Rijn, Matt van de, Malkin, David, Khan, Javed, Ignatius, Myron, Langenau, David M.

“…Growth and relapse are driven by cancer stem cells (CSCs) in a subset of tumors, yet mechanisms driving cancer cell fate choices, maintenance and self-renewal…”
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Vangl2/RhoA signaling regulates stem cell self-renewal programs and growth in Rhabdomyosarcoma by Hayes, Madeline N, Mccarthy, Karin, Jin, Alexander, Oliveira, Mariana L, Iyer, Sowmya, Garcia, Sara P, Sindiri, Sivasish, Gryder, Berkley, Motala, Zainab, Nielsen, G Petur Petur, Borg, Jean-Paul, van de Rijn, Matt, Malkin, David, Khan, Javed, Ignatius, Myron S, Langenau, David M

“…Tumor growth and relapse are driven by tumor propagating cells (TPCs). However, mechanisms regulating TPC fate choices, maintenance, and self-renewal are not…”
Get full text