Search Results - "Mota, Jose Mauricio"

Wnt/beta-catenin pathway: modulating anticancer immune response by Pai, Sachin Gopalkrishna, Carneiro, Benedito A, Mota, Jose Mauricio, Costa, Ricardo, Leite, Caio Abner, Barroso-Sousa, Romualdo, Kaplan, Jason Benjamin, Chae, Young Kwang, Giles, Francis Joseph

“…Wnt/β-catenin signaling, a highly conserved pathway through evolution, regulates key cellular functions including proliferation, differentiation, migration,…”
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Role of Capsaicin-Sensitive Primary Afferent Neurons and Non-protein Sulphydryl Groups on Gastroprotective Effect of Amifostine Against Ethanol-Induced Gastric Damage in Rats by Junqueira-Júnior, Jerônimo, Junqueira, Ana Flávia Torquato Araújo, Medeiros, Jand Venes R, Barbosa, Sergio Henrique Brito, Nogueira, Ana Carolina Pereira, Mota, José Maurício Segundo Correia, Santana, Ana Paula Macêdo, Brito, Gerly Anne C, Ribeiro, Ronaldo A, Lima-Júnior, Roberto César P, Souza, Marcellus H. L. P

“…Background Amifostine has been widely tested as a cytoprotective agent against a number of aggressors in different organs. Recently, a gastroprotective effect…”
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Measuring the unmeasurable: automated bone scan index as a quantitative endpoint in prostate cancer clinical trials by Mota, Jose Mauricio, Armstrong, Andrew J., Larson, Steven M., Fox, Josef J., Morris, Michael J.

“…Background Up to 90% of men with metastatic castration-resistant prostate cancer (mCRPC) will have a distribution of disease that includes bone metastases…”
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Scoring system for prediction of overall survival in patients with renal cell carcinoma T3aN0M0 by Suartz, Caio Vinícius, Cordeiro, Maurício Dener, Carvalho, Paulo Afonso, Gallucci, Fábio Pescarmona, Ribeiro‐Filho, Leopoldo Alves, Cardili, Leonardo, Sivaraman, Arjun, Audenet, François, Mota, José Mauricio, Nahas, William Carlos

“…Objective We aim to create a new score to predict postoperative overall survival in patients with nonmetastatic T3aN0 renal cell carcinoma. Methods We reviewed…”
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Paradoxical interaction between cancer and long-term postsepsis disorder: impairment of de novo carcinogenesis versus favoring the growth of established tumors by Leite, Caio Abner, Mota, Jose Mauricio, de Lima, Kalil Alves, Wanderley, Carlos Wagner, Nascimento, Leticia Almeida, Ferreira, Marcela Davoli, Silva, Camila Meirelles Souza, Colon, David Fernando, Sakita, Juliana Yumi, Kannen, Vinicius, Viacava, Paula Ramos, Begnami, Maria Dirlei, Lima-Junior, Roberto Cesar Pereira, Cordeiro de Lima, Vladmir Claudio, Alves-Filho, Jose Carlos, Cunha, Fernando Queiroz, Ribeiro, Ronaldo Albuquerque

“…Previous data have reported that the growth of established tumors may be facilitated by postsepsis disorder through changes in the microenvironment and immune…”
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The Rising Incidence of Younger Patients With Colorectal Cancer: Questions About Screening, Biology, and Treatment by Connell, Louise C., Mota, José Mauricio, Braghiroli, Maria Ignez, Hoff, Paulo M.

“…Opinion statement Colorectal cancer (CRC) is the third leading cancer diagnosed globally and an important cause of cancer-related mortality. Of interest, while…”
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Irinotecan- and 5-fluorouracil-induced intestinal mucositis: insights into pathogenesis and therapeutic perspectives by Ribeiro, Ronaldo A., Wanderley, Carlos W. S., Wong, Deysi V. T., Mota, José Maurício S. C., Leite, Caio A. V. G., Souza, Marcellus H. L. P., Cunha, Fernando Q., Lima-Júnior, Roberto C. P.

“…Purpose Intestinal mucositis and diarrhea are common manifestations of anticancer regimens that include irinotecan, 5-fluorouracil (5-FU), and other cytotoxic…”
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Induction of COX-2 expression by acrolein in the rat model of hemorrhagic cystitis by Macedo, Francisco Yuri Bulcão, Baltazar, Fátima, Mourão, Lívia Cajaseiras, Almeida, Paulo Roberto Carvalho, Mota, José Mauricio S.C., Schmitt, Fernando C., Ribeiro, Ronaldo A.

“…Acrolein (ACR) is a urinary metabolite of cyclophosphamide (CPS) and ifosfamide (IFS), which has been demonstrated to be the causative agent of hemorrhagic…”
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Complications from carcinoid syndrome: review of the current evidence by Mota, José Mauricio, Sousa, Luana Guimarães, Riechelmann, Rachel P

“…Patients with well-differentiated neuroendocrine tumours may develop carcinoid syndrome (CS), which is characterised by flushing, abdominal cramps, diarrhoea,…”
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CCR5-Positive Inflammatory Monocytes are Crucial for Control of Sepsis by Castanheira, Fernanda Vargas e Silva, de Lima, Kalil Alves, Cebinelli, Guilherme Cesar Martelossi, Sônego, Fabiane, Kanashiro, Alexandre, Colon, David-Fernando, Borges, Vanessa, Czaikoski, Paula Giselle, Mota, José Mauricio, Cunha, Thiago Mattar, Alves-Filho, José Carlos, Liew, Foo Y, Cunha, Fernando Queiroz

“…ABSTRACTNeutrophils and inflammatory monocytes control sepsis by migration to the site of infection via their chemokine receptors. CCR5 is a chemokine receptor…”
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Gastrointestinal dysmotility in 5-fluorouracil-induced intestinal mucositis outlasts inflammatory process resolution by Soares, Pedro M. G., Mota, José Maurício S. C., Gomes, Antoniella S., Oliveira, Ricardo B., Assreuy, Ana Maria S., Brito, Gerly Anne C., Santos, Armênio A., Ribeiro, Ronaldo A., Souza, Marcellus H. L. P.

“…Aim To evaluate gastrointestinal motility during 5-fluorouracil (5-FU)-induced intestinal mucositis. Materials and methods Wistar rats received 5-FU (150 mg kg…”
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Neutrophil Extracellular Traps Induce Organ Damage during Experimental and Clinical Sepsis by Czaikoski, Paula Giselle, Mota, José Maurício Segundo Correia, Nascimento, Daniele Carvalho, Sônego, Fabiane, Castanheira, Fernanda Vargas e Silva, Melo, Paulo Henrique, Scortegagna, Gabriela Trentin, Silva, Rangel Leal, Barroso-Sousa, Romualdo, Souto, Fabrício Oliveira, Pazin-Filho, Antonio, Figueiredo, Florencio, Alves-Filho, José Carlos, Cunha, Fernando Queiróz

“…Organ dysfunction is a major concern in sepsis pathophysiology and contributes to its high mortality rate. Neutrophil extracellular traps (NETs) have been…”
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Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer by Zhang, Zeda, Karthaus, Wouter R., Lee, Young Sun, Gao, Vianne R., Wu, Chao, Russo, Joshua W., Liu, Menghan, Mota, Jose Mauricio, Abida, Wassim, Linton, Eliot, Lee, Eugine, Barnes, Spencer D., Chen, Hsuan-An, Mao, Ninghui, Wongvipat, John, Choi, Danielle, Chen, Xiaoping, Zhao, Huiyong, Manova-Todorova, Katia, de Stanchina, Elisa, Taplin, Mary-Ellen, Balk, Steven P., Rathkopf, Dana E., Gopalan, Anuradha, Carver, Brett S., Mu, Ping, Jiang, Xuejun, Watson, Philip A., Sawyers, Charles L.

“…Despite the development of second-generation antiandrogens, acquired resistance to hormone therapy remains a major challenge in treating advanced prostate…”
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Inflammatory intestinal damage induced by 5-fluorouracil requires IL-4 by Soares, Pedro M.G., Mota, José Maurício S.C., Souza, Emmanuel P., Justino, Priscilla F.C., Franco, Alvaro X., Cunha, Fernando Q., Ribeiro, Ronaldo A., Souza, Marcellus H.L.P.

“…► We evaluate the participation of the IL-4 on the 5-FU-induced intestinal mucositis. ► 5-FU induced significant epithelial intestinal damage. ► IL-4−/− mice…”
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Pan-cancer Analysis of CDK12 Alterations Identifies a Subset of Prostate Cancers with Distinct Genomic and Clinical Characteristics by Nguyen, Bastien, Mota, Jose Mauricio, Nandakumar, Subhiksha, Stopsack, Konrad H., Weg, Emily, Rathkopf, Dana, Morris, Michael J., Scher, Howard I., Kantoff, Philip W., Gopalan, Anuradha, Zamarin, Dmitriy, Solit, David B., Schultz, Nikolaus, Abida, Wassim

“…CDK12 genomic alterations occur in several tumor types, but little is known about their oncogenic role and clinical significance. To describe the landscape of…”
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Daro-PET: A phase 2 trial of darolutamide as a prostate-specific membrane antigen (PSMA) expression enhancer in patients with localized prostate cancer by Mota, Jose Mauricio, Mosci, Camila, Vasconcellos, Jéssica, Hemerly, Thiago Souto, Silva Neto, Deusdedit Cortêz Vieira, Brandao, Luis Felipe, Srougi, Victor, Ramos, Rodrigo Nalio, Cunha, Isabela Werneck

“…TPS348 Background: Prostate specific membrane antigen (PSMA) has been explored as a target in imaging studies using positron emission tomography (PSMA-PET) to…”
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Role of platelet-activating factor in the pathogenesis of 5-fluorouracil-induced intestinal mucositis in mice by Soares, Pedro M. G., Lima-Junior, Roberto C. P., Mota, José Maurício S. C., Justino, Priscilla F. C., Brito, Gerly Anne C., Ribeiro, Ronaldo A., Cunha, Fernando Q., Souza, Marcellus H. L. P.

“…Purpose Gastrointestinal mucositis is a common side effect of cancer chemotherapy. Platelet-activating factor (PAF) is produced during gut inflammation. There…”
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Association of primary tumor radiomic phenotypes and outcomes in patients (pts) with metastatic renal cell clear cell carcinoma (mRCC) treated with cytoreductive nephrectomy (CN) by Cunha, Mateus Trinconi, Stangler, Lucas, Freire, Pedro, Pinto, Paulo Victor Alves, Coelho, Fernando Morbeck Almeida, Viana, Públio, Cordeiro, Mauricio, Nahas, William Carlos, Mota, Jose Mauricio

“…622 Background: Despite the advances in systemic therapy for mRCC, CN may benefit a subset of pts. We investigated the correlation of clinical outcomes with…”
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Clinical characteristics and treatment outcomes of advanced penile squamous cell carcinoma: Real-world evidence from a tertiary cancer center in Brazil by Parrela, Vinicius Cruz, Polho, Gabriel Berlingieri, Andrade, Matheus de Oliveira, Almeida Moreno Santos, Rogerio, Alves, Gustavo Luis, Arneiro, Matheus Henrique Juliani, Felix, Vitor Hugo, Hidalgo Filho, Cassio Murilo, Cazellato Pacheco de Mello, Murilo, Mota, Jose Mauricio

“…e17025 Background: Penile cancer is a rare disease worldwide. However, Brazil has an annual incidence of 1.5 cases per 100,000 inhabitants, representing 2% of…”
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Subcutaneous (SC) nivolumab (NIVO) vs intravenous (IV) NIVO in patients with previously treated advanced or metastatic clear cell renal cell carcinoma (ccRCC): Safety and patient-reported outcomes (PROs) of the randomized phase 3 CheckMate 67T trial by Bourlon, Maria T., Albiges, Laurence, Chacon, Matias Rodrigo, Cutuli, Hernan, Mota, Jose Mauricio, Magri, Ignacio, Burotto, Mauricio, Luz, Murilo, Menezes, Juliana, Yanez Ruiz, Eduardo Patricio, Maruzzo, Marco, Bracarda, Sergio, Rathod, Dhanrajsinh, Yu, Zhuoxin, Gurm, Balmeet, Dixon, Matthew, George, Saby

“…Abstract only 4532 Background: CheckMate 67T (NCT04810078), a multicenter, randomized, open-label, phase 3 study, evaluated pharmacokinetics and objective…”
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