Increased EPA levels in serum phospholipids of humans after four weeks daily ingestion of one portion chicken fed linseed and rapeseed oil

Since the amounts of arachidonic acid (AA) and EPA in food may have implications for human health, we investigated whether a small change in chicken feed influenced the blood lipid concentration in humans ingesting the chicken. Forty-six young healthy volunteers (age 20-29) were randomly allocated i...

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Bibliographic Details
Published in:	Lipids in health and disease Vol. 11; no. 1; p. 104
Main Authors:	Haug, Anna, Nyquist, Nicole F, Mosti, Therese J, Andersen, Malin, Høstmark, Arne T
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 22-08-2012 BioMed Central BMC
Subjects:	Adult Animal Feed Animal feeding and feeds Animals Arachidonic acid Arachidonic Acid - blood Blood cholesterol Body weight C-reactive protein Cancer Chicken meat Chickens - metabolism Cholesterol Costs (Law) Diet Double-Blind Method Eicosapentaenoic Acid - blood EPA Fatty acids Fatty Acids - analysis Fatty Acids - blood Fatty Acids, Monounsaturated Feed Female Food Analysis Humans Linseed oil Linseed Oil - administration & dosage Lipids Low density lipoproteins Male Meat - analysis n-3 fatty acids Omega-3 fatty acids Phospholipids Phospholipids - blood Physiological aspects Plant Oils - administration & dosage Poultry Rapeseed Oil Serum phospholipids Soybean Soybean oil Unsaturated fatty acids Young Adult Norway
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Summary:	Since the amounts of arachidonic acid (AA) and EPA in food may have implications for human health, we investigated whether a small change in chicken feed influenced the blood lipid concentration in humans ingesting the chicken. Forty-six young healthy volunteers (age 20-29) were randomly allocated into two groups in a double-blind dietary intervention trial, involving ingestion of about 160 g chicken meat per day for 4 weeks. The ingested meat was either from chickens given a feed concentrate resembling the commercial chicken feed, containing 4% soybean oil (SO), or the meat was from chickens given a feed where the soybean oil had been replaced by 2% rapeseed oil plus 2% linseed oil (RLO).Serum total cholesterol, LDL and HDL cholesterol, triacylglycerols, serum phospholipid fatty acid concentration, blood pressure, body weight and C-reactive protein were determined at baseline and post-intervention. In subjects consuming chicken meat from the RLO group there was a significantly (p < 0.001) increased concentration of EPA in serum phospholipids, and a reduced ratio between AA and EPA. The participants that had a low% of EPA + DHA in serum phospholipids (less than 4.6%), all increased their% of EPA + DHA after the four week intervention period when consuming the RLO chicken. No significant response differences in cholesterol, triacylglycerol, C-reactive protein, body weight or blood pressure were observed between the groups. This trial demonstrates that a simple change in chicken feed can have beneficial effects on amount of EPA and the AA/EPA ratio in human serum phospholipids.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Undefined-3
ISSN:	1476-511X 1476-511X
DOI:	10.1186/1476-511X-11-104