Search Results - "Mostafa, Sara M."

Synthesis, Characterization, and In Vivo Study of Some Novel 3,4,5-Trimethoxybenzylidene-hydrazinecarbothioamides and Thiadiazoles as Anti-Apoptotic Caspase-3 Inhibitors by Mostafa, Sara M, Aly, Ashraf A, Bräse, Stefan, Nieger, Martin, Abdelhafez, Sara Mohamed Naguib, Abdelzaher, Walaa Yehia, Abdelhafez, El-Shimaa M N

“…The present study aims to discover novel derivatives as antiapoptotic agents and their protective effects against renal ischemia/reperfusion. Therefore, a…”
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Autoxidation of 4-Hydrazinylquinolin-2(1 H )-one; Synthesis of Pyridazino[4,3- c :5,6- c ']diquinoline-6,7(5 H ,8 H )-diones by Mostafa, Sara M, Aly, Ashraf A, Hassan, Alaa A, Osman, Esraa M, Bräse, Stefan, Nieger, Martin, Ibrahim, Mahmoud A A, Mohamed, Asmaa H

“…An efficient synthesis of a series of pyridazino[4,3- :5,6- ']diquinolines was achieved via the autoxidation of 4-hydrazinylquinolin-2(1 )-ones. IR, NMR ( H…”
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Microwave-assisted reactions: Efficient and versatile one-step synthesis of 8-substituted xanthines and substituted pyrimidopteridine-2,4,6,8-tetraones under controlled microwave heating by Mekheimer, Ramadan Ahmed, Hayallah, Alaa M., Moustafa, Moustafa Sherief, Al-Mousawi, Saleh Mohammed, Abd-Elmonem, Mohamed, Mostafa, Sara M., Abo Elsoud, Fatma A., Sadek, Kamal Usef

“…We report herein a simple and efficient one-step synthesis of 8-substituted xanthines and substituted pyrimidopteridine-2,4,6,8-tetraones via reaction of…”
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Synthesis of (E)-2,5-disubstituted 1,3,4-thiadiazolyl-2,3-diphenylpropenones from alkenylidene-hydrazinecarbothioamides by Hassan, Alaa A., Abdel-Latif, Fathy F., Nour El-Din, Ahmed M., Mostafa, Sara M., Nieger, Martin, Bräse, Stefan

“…Conjugated alkenylidene-hydrazinecarbothioamides react in high yield with 2,3-diphenylcyclopropenone to give a series of (E)-2,5-disubstituted…”
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Heterocycles from cyclopropenones by Aly, Ashraf A, Hassan, Alaa A, Mostafa, Sara M, Mohamed, Asmaa. H, Osman, Esraa M, Nayl, AbdElAziz A

“…Great attention has been paid to cyclopropenones as they are present in many natural sources. Various synthesized cyclopropenone derivatives also show a wide…”
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Novel quinoline/thiazinan-4-one hybrids; design, synthesis, and molecular docking studies as potential anti-bacterial candidates against MRSA by Mohamed, Asmaa H, Mostafa, Sara M, Aly, Ashraf A, Hassan, Alaa A, Osman, Esraa M, Nayl, AbdElAziz A, Brown, Alan B, Abdelhafez, Elshimaa M. N

“…In an attempt to develop effective and safe antibacterial agents, we synthesized novel thiazinanones by combining the quinolone scaffold and the…”
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An efficient approach for the synthesis of novel series of 1,3-dihydrospiro[indene-2,6ʹ-[1,3]thiazine] derivatives by Mostafa, Sara M., Aly, Ashraf A., Bräse, Stefan, Mohamed, Asmaa H.

“…Facile synthesis of trimethoxyphenyl-1,3-dihydrospiro[indene-2,6ʹ-[1,3]thiazines was achieved during reaction of trimethoxyphenyl hydrazinecarbonothioyl…”
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Facile synthesis of hydrazono bis-4-oxothiazolidines by Mostafa, Sara M., Aly, Ashraf A., Bräse, Stefan, Nieger, Martin, Mohamed, Asmaa H.

“…Herein, we reported on a new series of hydrazono bis-4-oxothiazolidines during the reaction of (hydrazinecarbonothioyl)hydrazinecarbothioamides with dimethyl…”
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Metal complexes of new thiocarbohydrazones of Cu(I), Co(II), and Ni(II); identification by NMR, IR, mass, UV spectra, and DFT calculations by Aly, Ashraf A., Abdallah, Elham M., Ahmed, Salwa A., Awad, Mohamed K., Rabee, Mai M., Mostafa, Sara M., Bräse, Stefan

“…Substituted thiocarbohydrazones were synthesized to study their complexation capability towards Cu(I), Co(II), and Ni(II) salts. The Cu(I) complexes showed…”
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Synthesis of 3,3′-methylenebis(4-hydroxyquinolin-2(1H)-ones) of prospective anti-COVID-19 drugs by Aly, Ashraf A., Hassan, Alaa A., Mohamed, Asmaa H., Osman, Esraa M., Bräse, Stefan, Nieger, Martin, Ibrahim, Mahmoud A. A., Mostafa, Sara M.

“…During formylation of 2-quinolones by DMF/Et 3 N mixture, the unexpected 3,3′-methylenebis(4-hydroxyquinolin-2(1 H )-ones) were formed. The discussed mechanism…”
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Formation of thiadiazole, thiadiazine, thiadiazepine and pyrazole derivatives in the reaction of 2,4-disubstituted thiosemicarbazides with tetracyanoethylene by Hassan, Alaa A., Aly, Ashraf A., Mostafa, Sara M., Döpp, Dietrich

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Recent Heterocyclic Compounds from (1,3-Dioxo-2,3-dihydro-1H-inden-2-ylidene)propanedinitrile by Hassan, Alaa A., Mostafa, Sara M.

“…This review summarizes the literatures dealing with the synthesis of some important nitrogen or nitrogen/sulfur heterocyclic, spiroheterocyclic, and fused…”
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A simple and efficient synthesis of 3-amino-5-benzyl-6-phenylpyridazine-4-carbonitrile by Hassan, Alaa A., Mostafa, Sara M., Bräse, Stefan, Nieger, Martin

“…3-Amino-5-benzyl-6-pyridazine-4-carbonitrile has been synthesized by the reaction of 4-substituted thiosemicarbazides with…”
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Efficient and Facile Synthesis of Substituted Aminothiadiazolylhydrazonoindolin-2-ones by Hassan, Alaa A., Abdel-Latif, Fathy F., Abdel-Aziz, Mohamed, Mostafa, Sara M., Bräse, Stefan, Nieger, Martin

“…New series of substituted aminothiadiazolylhydrazonoindolin‐2‐ones were prepared in high yields (89–94%) via the cyclocondensation of thiocarbonohydrazides…”
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(Substituted Ylidene)Amino‐2‐Oxo‐Indolylidene Thioureas and Bis(2‐Oxo‐Indolylidene)Urea from (Ylidene)Thiocarbonohydrazides and Isatylidene Malononitrile by Hassan, Alaa A., Mohamed, Shaaban K., Abdel‐Latif, Fathy F., Mostafa, Sara M., Abdel‐Aziz, Mohamed, Mague, Joel T., Akkurt, Mehmet, Bräse, Stefan, Nieger, Martin

“…A simple and efficient synthesis of (substituted ylidene)(2‐oxoindolylidene)thiocarbohydrazones and bis(2‐oxoindolylidene)urea was achieved by the reaction of…”
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New s-Triazine/Tetrazole conjugates as potent antifungal and antibacterial agents: Design, molecular docking and mechanistic study by Mekheimer, Ramadan Ahmed, Abuo-Rahma, Gamal El-Din A., Abd-Elmonem, Mohamed, Yahia, Ramadan, Hisham, Mohamed, Hayallah, Alaa M., Mostafa, Sara M., Abo-Elsoud, Fatma A., Sadek, Kamal Usef

“…•New s-Triazine/Tetrazole hybrid molecules have been synthesized via simple and efficient multi-component reaction.•The synthesized scaffolds showed excellent…”
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Recent developments in the synthesis of hybrid heterocycles, a promising approach to develop multi-target antibacterial agents by Sadek, Kamal Usef, Mekheimer, Ramadan Ahmed, Abd-Elmonem, Mohamed, Abo-Elsoud, Fatma A., Hayallah, Alaa M., Mostafa, Sara M., Abdellattif, Magda H., Abourehab, Mohammed A.S., Farghaly, Thoraya A., Elkamhawy, Ahmed

“…•The synthesis of five-five, five-six and six-six antibacterial hybrid heterocycles.•The Docking studies and mechanism of action for synthesized compounds.•The…”
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New Quinoline-2-one/thiazolium bromide Derivatives; Synthesis, Characterization and Mechanism of Formation by Mostafa, Sara M., Aly, Ashraf A., Sayed, Samia M., Raslan, Mohamed A., Ahmed, Amira E., Nafady, Ayman, Ishak, Esam A., Shawky, Ahmed M., Abdelhafez, El-Shimaa M.N.

“…•Reaction of 3-thiosemicarbazides derived by 2-quinolones with 2-bromoacetophenones•Synthesis of new quinoline-2-one/thiazolium bromide derivatives•Structure…”
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Tetracyanoethylene as a mediator and building block in synthesis of 5-substituted amino-1,3,4-thiadiazolyl-1H-pyrazole derivatives by Hassan, Alaa A., Mohamed, Shaaban K., Abdel-Latif, Fathy F., Mostafa, Sara M., Mague, Joel T., Akkurt, Mehmet, Abdel-Aziz, Mohamed

“…[Display omitted] The conversion of thiocarbonohydrazides to 5-substituted amino-1,3,4-thiadiazolyl-1H-pyrazoles in one-step was achieved via the reaction with…”
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Heterocyclization of thiocarbonohydrazides：Facile synthesis of 5-unsubstituted-1,3,4-thiadiazoles by Hassan, Alaa A., Abdel-Latif, Fathy F., Aziz, Mohamed Abdel, Mostafa, Sara M., Bräse, Stefan, Nieger, Martin

“…2-（Hydrazinecarbothioyl）-N-substituted hydrazinecarbothioamides react with 2,3,5,6-tetrachloro-1,4-benzoquinone in high yields in a novel fast and facile…”
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