Search Results - "Moss, Fraser J"

Novel RPTPγ and RPTPζ splice variants from mixed neuron-astrocyte hippocampal cultures as well as from the hippocampi of newborn and adult mice by Taki, Sara, Boron, Walter F, Moss, Fraser J

“…Receptor protein tyrosine phosphatases γ and ζ (RPTPγ and RPTPζ) are transmembrane signaling proteins with extracellular carbonic anhydrase-like domains that…”
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Carbon dioxide transport across membranes by Michenkova, Marie, Taki, Sara, Blosser, Matthew C, Hwang, Hyea J, Kowatz, Thomas, Moss, Fraser J, Occhipinti, Rossana, Qin, Xue, Sen, Soumyo, Shinn, Eric, Wang, Dengke, Zeise, Brian S, Zhao, Pan, Malmstadt, Noah, Vahedi-Faridi, Ardeschir, Tajkhorshid, Emad, Boron, Walter F

“…Carbon dioxide (CO ) movement across cellular membranes is passive and governed by Fick's law of diffusion. Until recently, we believed that gases cross…”
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Aquaporin-7: A Dynamic Aquaglyceroporin With Greater Water and Glycerol Permeability Than Its Bacterial Homolog GlpF by Moss, Fraser J, Mahinthichaichan, Paween, Lodowski, David T, Kowatz, Thomas, Tajkhorshid, Emad, Engel, Andreas, Boron, Walter F, Vahedi-Faridi, Ardeschir

“…oocytes expressing human aquaporin-7 (AQP7) exhibit greater osmotic water permeability and H-glycerol uptake vs. those expressing the bacterial glycerol…”
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Hsp47 promotes biogenesis of multi-subunit neuroreceptors in the endoplasmic reticulum by Wang, Ya-Juan, Di, Xiao-Jing, Zhang, Pei-Pei, Chen, Xi, Williams, Marnie P, Han, Dong-Yun, Nashmi, Raad, Henderson, Brandon J, Moss, Fraser J, Mu, Ting-Wei

“…Protein homeostasis (proteostasis) deficiency is an important contributing factor to neurological and metabolic diseases. However, how the proteostasis network…”
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Linaclotide improves gastrointestinal transit in cystic fibrosis mice by inhibiting sodium/hydrogen exchanger 3 by McHugh, Daniel R, Cotton, Calvin U, Moss, Fraser J, Vitko, Megan, Valerio, Dana M, Kelley, Thomas J, Hao, Shuyu, Jafri, Anjum, Drumm, Mitchell L, Boron, Walter F, Stern, Robert C, McBennett, Kimberly, Hodges, Craig A

“…Gastrointestinal dysfunction in cystic fibrosis (CF) is a prominent source of pain among patients with CF. Linaclotide, a guanylate cyclase C (GCC) receptor…”
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Nicotine normalizes intracellular subunit stoichiometry of nicotinic receptors carrying mutations linked to autosomal dominant nocturnal frontal lobe epilepsy by Son, Cagdas D, Moss, Fraser J, Cohen, Bruce N, Lester, Henry A

“…Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) is linked with high penetrance to several distinct nicotinic receptor (nAChR) mutations. We studied…”
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Carbonic anhydrases enhance activity of endogenous Na‐H exchangers and not the electrogenic Na/HCO3 cotransporter NBCe1‐A, expressed in Xenopus oocytes by Moss, Fraser J., Boron, Walter F.

“…Key points According to the HCO3− metabolon hypothesis, direct association of cytosolic carbonic anhydrases (CAs) with the electrogenic Na/HCO3 cotransporter…”
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Förster resonance energy transfer (FRET) correlates of altered subunit stoichiometry in cys-loop receptors, exemplified by nicotinic α4β2 by Srinivasan, Rahul, Richards, Christopher I, Dilworth, Crystal, Moss, Fraser J, Dougherty, Dennis A, Lester, Henry A

“…We provide a theory for employing Förster resonance energy transfer (FRET) measurements to determine altered heteropentameric ion channel stoichiometries in…”
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Immunohistochemical localization of receptor protein tyrosine phosphatase γ in mouse renal proximal tubule, thick ascending limb and distal convoluted tubule by Deverakonda, Abhi N., Gilker, Eva, Boron, Walter F., Moss, Fraser J.

“…Most normal physiological processes require that both intracellular (i) and extracellular (o) pH be maintained within a tight range. pHo is contingent on…”
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Carbonic anhydrases enhance activity of endogenous Na-H exchangers and not the electrogenic Na/HCO 3 cotransporter NBCe1-A, expressed in Xenopus oocytes by Moss, Fraser J, Boron, Walter F

“…According to the metabolon hypothesis, direct association of cytosolic carbonic anhydrases (CAs) with the electrogenic Na/HCO cotransporter NBCe1-A speeds…”
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Carbonic anhydrase and soluble adenylate cyclase regulation of cystic fibrosis cellular phenotypes by Boyne, Kathleen, Corey, Deborah A, Zhao, Pan, Lu, Binyu, Boron, Walter F, Moss, Fraser J, Kelley, Thomas J

“…Several aspects of the cell biology of cystic fibrosis (CF) epithelial cells are altered including impaired lipid regulation, disrupted intracellular…”
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Inhibition by acetazolamide of reactivated carbonic anhydrase activity in a receptor protein tyrosine phosphatase γ (RPTPγ) mutant by Duong, Phu C., Moss, Fraser J., Skelton, Lara A., Musa‐Aziz, Raif, Boron, Walter F.

“…HCO3− reabsorption (JHCO3) by the renal proximal tubule (PT) is acutely regulated by basolateral [CO2]BL or [HCO3−]BL, but not by pHBL. RPTPγ is a…”
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Nicotine up-regulates α4β2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning by Srinivasan, Rahul, Pantoja, Rigo, Moss, Fraser J., Mackey, Elisha D.W., Son, Cagdas D., Miwa, Julie, Lester, Henry A.

“…The up-regulation of α4β2* nicotinic acetylcholine receptors (nAChRs) by chronic nicotine is a cell-delimited process and may be necessary and sufficient for…”
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GABA transporter function, oligomerization state, and anchoring: correlates with subcellularly resolved FRET by Moss, Fraser J, Imoukhuede, P I, Scott, Kimberly, Hu, Jia, Jankowsky, Joanna L, Quick, Michael W, Lester, Henry A

“…The mouse gamma-aminobutyric acid (GABA) transporter mGAT1 was expressed in neuroblastoma 2a cells. 19 mGAT1 designs incorporating fluorescent proteins were…”
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Effect of Simultaneously Replacing Putative TM6 and TM12 of Human NBCe1-A with Those from NBCn1 on Surface Abundance in Xenopus Oocytes by Chen, Li-Ming, Qin, Xue, Moss, Fraser J., Liu, Ying, Boron, Walter F.

“…HCO 3 − translocation across the plasma membrane via the electrogenic Na/HCO 3 − cotransporter NBCe1 plays an important role in intracellular pH regulation and…”
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Ezrin Mediates Tethering of the γ-Aminobutyric Acid Transporter GAT1 to Actin Filaments Via a C-Terminal PDZ-Interacting Domain by Imoukhuede, P.I., Moss, Fraser J., Michael, Darren J., Chow, Robert H., Lester, Henry A.

“…A high density of neurotransmitter transporters on axons and presynaptic boutons is required for the efficient clearance of neurotransmitters from the synapse…”
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The novel product of a five-exon stargazin-related gene abolishes CaV2.2 calcium channel expression by Moss, Fraser J., Viard, Patricia, Davies, Anthony, Bertaso, Federica, Page, Karen M., Graham, Alex, Cantí, Carles, Plumpton, Mary, Plumpton, Christopher, Clare, Jeffrey J., Dolphin, Annette C.

“…We have cloned and characterized a new member of the voltage‐dependent Ca2+ channel γ subunit family, with a novel gene structure and striking properties…”
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Distinguishing among HCO3 −, CO3 =, and H+ as Substrates of Proteins That Appear To Be “Bicarbonate” Transporters by Lee, Seong-Ki, Occhipinti, Rossana, Moss, Fraser J., Parker, Mark D., Grichtchenko, Irina I., Boron, Walter F.

“…Significance Statement SLC4 proteins play numerous important roles in the kidneys and elsewhere because they translocate what appears to be bicarbonate through…”
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Quantitation of a neutral‐buoyancy assay (NBA) to estimate transmembrane N 2 flux by Moss, Fraser J., Zeise, Brian, Huffman, Dale, O’Neill, Steven, Boron, Walter F.

“…Abstract only Several assays exist for CO 2 , O 2 and NH 3 permeability, but a major technical void has been the absence of an assay for the transmembrane…”
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The First N2 Channels Identified by a Novel Technique for Assessing Nitrogen Gas Efflux from Oocytes by Moss, Fraser J, Zeise, Brian, Huffman, Dale, Yilmaz, Mehmet, Boron, Walter F.

“…Decompression illness (DCI) is a serious problem for both divers and pilots. Divers must schedule their ascents to minimize the risk of nitrogen (N2) bubble…”
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