Search Results - "Moss, Charlotte"
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Associations between immune-suppressive and stimulating drugs and novel COVID-19-a systematic review of current evidence
Published in Ecancermedicalscience (27-03-2020)“…Cancer and transplant patients with COVID-19 have a higher risk of developing severe and even fatal respiratory diseases, especially as they may be treated…”
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Markers of the ageing macrophage: a systematic review and meta-analysis
Published in Frontiers in immunology (13-07-2023)“…Ageing research is establishing macrophages as key immune system regulators that undergo functional decline. Due to heterogeneity between species and tissue…”
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An assessment of the use of patient reported outcome measurements (PROMs) in cancers of the pelvic abdominal cavity: identifying oncologic benefit and an evidence-practice gap in routine clinical practice
Published in Health and quality of life outcomes (15-01-2021)“…Patient reported outcome measurements (PROMs) are emerging as an important component of patient management in the cancer setting, providing broad perspectives…”
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The experience of surgical cancer patients during the COVID-19 pandemic at a large cancer centre in London
Published in Supportive care in cancer (01-05-2024)“…Background The COVID-19 pandemic has had an enormous impact on the experiences of patients across all health disciplines, especially those of cancer patients…”
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Frequency of Pathogenic Germline Variants in CDH1, BRCA2, CHEK2, PALB2, BRCA1 , and TP53 in Sporadic Lobular Breast Cancer
Published in Cancer epidemiology, biomarkers & prevention (01-07-2019)“…Invasive lobular breast cancer (ILC) accounts for approximately 15% of invasive breast carcinomas and is commonly associated with lobular carcinoma (LCIS)…”
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Exploring the role of E. faecalis enterococcal polysaccharide antigen (EPA) and lipoproteins in evasion of phagocytosis
Published in Molecular microbiology (01-08-2024)“…Enterococcus faecalis is an opportunistic pathogen frequently causing nosocomial infections. The virulence of this organism is underpinned by its capacity to…”
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Aging-related defects in macrophage function are driven by MYC and USF1 transcriptional programs
Published in Cell reports (Cambridge) (23-04-2024)“…Macrophages are central innate immune cells whose function declines with age. The molecular mechanisms underlying age-related changes remain poorly understood,…”
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Frequency of pathogenic germline variants in BRCA1, BRCA2, PALB2, CHEK2 and TP53 in ductal carcinoma in situ diagnosed in women under the age of 50 years
Published in Breast cancer research : BCR (06-05-2019)“…Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive ductal breast cancer, and approximately 20% of screen-detected tumours are pure DCIS…”
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Is There a Role for Exercise When Treating Patients with Cancer with Immune Checkpoint Inhibitors? A Scoping Review
Published in Cancers (14-10-2022)“…The impact of using exercise as a non-pharmacological intervention in patients with cancer receiving immune checkpoint inhibitors (ICIs) is not well known. Our…”
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Acute hospital preoperative assessment redesign: streamlining the patient pathway and reducing on-the-day surgery cancellations
Published in BMJ open quality (01-09-2021)“…IntroductionAvoidable surgery cancellations in an acute trust were often attributed to inadequate preoperative assessment. These assessments, undertaken…”
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Cancer staff in an NHS cancer center: infections, vaccination, stress and well-being support during the COVID-19 pandemic
Published in Future oncology (London, England) (01-06-2022)“…To evaluate the impact of the pandemic on the well-being of cancer staff and determine the uptake of opt-in mitigation strategies. Staff at Guy's Cancer Centre…”
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Cohort profile: King's Health Partners bladder cancer biobank
Published in BMC cancer (25-09-2020)“…Bladder cancer (BC) is the 9th most common cancer worldwide, but little progress has been made in improving patient outcomes over the last 25 years. The King's…”
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Factors Affecting COVID-19 Outcomes in Cancer Patients: A First Report From Guy's Cancer Center in London
Published in Frontiers in oncology (22-07-2020)“…There is insufficient evidence to support clinical decision-making for cancer patients diagnosed with COVID-19 due to the lack of large studies. We used data…”
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The need for supportive mental wellbeing interventions in bladder cancer patients: A systematic review of the literature
Published in PloS one (28-01-2021)“…There is an increased awareness of the effect of a bladder cancer diagnosis and its treatments on the mental wellbeing of patients. However, few studies have…”
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Assessing the quality of patient-reported outcome measurements for gynecological cancers: a systematic review
Published in Future oncology (London, England) (01-03-2023)“…To provide perspective on patient-reported outcome measurement (PROM) instruments to adopt in patients diagnosed with gynecological cancers. A systematic…”
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The acetaminophen metabolite N-acetyl-p-benzoquinone imine (NAPQI) inhibits glutathione synthetase in vitro; a clue to the mechanism of 5-oxoprolinuric acidosis?
Published in Xenobiotica (01-02-2017)“…1. Metabolic acidosis due to accumulation of l-5-oxoproline is a rare, poorly understood, disorder associated with acetaminophen treatment in malnourished…”
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Anxiety and depression in patients with non-site-specific cancer symptoms: data from a rapid diagnostic clinic
Published in Frontiers in oncology (03-06-2024)“…Rapid diagnostic clinics (RDCs) provide a streamlined holistic pathway for patients presenting with non-site specific (NSS) symptoms concerning of malignancy…”
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One Piece of the Jigsaw for the Cancer Recovery Strategy: Prevalence of COVID-19 in Patients With Cancer
Published in Cancer control (01-07-2020)“…COVID-19 has forced governments to make drastic changes to healthcare systems. To start making informed decisions about cancer care, we need to understand the…”
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COVID-19 Risk Factors for Cancer Patients: A First Report with Comparator Data from COVID-19 Negative Cancer Patients
Published in Cancers (19-05-2021)“…Very few studies investigating COVID-19 in cancer patients have included cancer patients as controls. We aimed to identify factors associated with the risk of…”
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Tribbles 3 deficiency promotes atherosclerotic fibrous cap thickening and macrophage-mediated extracellular matrix remodelling
Published in Frontiers in cardiovascular medicine (26-08-2022)“…Tribbles 3 (TRIB3) modulates lipid and glucose metabolism, macrophage lipid uptake, with a gain-of-function variant associated with increased cardiovascular…”
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