Search Results - "Mosley, Scott A."

Institutional profile: University of Florida Health Personalized Medicine Program by Cavallari, Larisa H, Weitzel, Kristin W, Elsey, Amanda R, Liu, Xinyue, Mosley, Scott A, Smith, Donald M, Staley, Benjamin J, Winterstein, Almut G, Mathews, Carol A, Franchi, Francesco, Rollini, Fabiana, Angiolillo, Dominick J, Starostik, Petr, Clare-Salzler, Michael J, Nelson, David R, Johnson, Julie A

“…The University of Florida (UF) Health Personalized Medicine Program launched in 2012 with genotyping for clopidogrel response at UF Health Shands Hospital. We…”
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A randomized, cross‐over trial of metoprolol succinate formulations to evaluate PK and PD end points for therapeutic equivalence by Mosley, Scott A., Kim, Sarah, El Rouby, Nihal, Lingineni, Karthik, Esteban, Valvanera Vozmediano, Gong, Yan, Chen, Yiqing, Estores, David, Feng, Kairui, Kim, Hyewon, Kinjo, Minori, Langaee, Taimour, Li, Zhichuan, Schmidt, Siegfried O. F., Johnson, Julie A., Frye, Reginald F., Fang, Lanyan (Lucy), Zhao, Liang, Binkley, Philip F., Schmidt, Stephan, Cavallari, Larisa H.

“…There are limited comparison data throughout the dosing interval for generic versus brand metoprolol extended‐release (ER) tablets. We compared the…”
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Determination of Minimum Effective Dose and Optimal Dosing Schedule for Liposomal Curcumin in a Xenograft Human Pancreatic Cancer Model by MACH, Claire M, MATHEW, Lata, MOSLEY, Scott A, KURZROCK, Razelle, SMITH, Judith A

“…Background: Curcumin is a food chemical present in tumeric (Curcuma longa) that has pharmacological activity to suppress carcinogenesis and inhibits multiple…”
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Ligand-specific pharmacogenetic effects of nonsynonymous mutations by Morningstar-Kywi, Noam, Haworth, Ian S., Mosley, Scott A.

“…In pharmacogenomics, variable receptor phenotypes, resulting from genetic polymorphisms, are often described as a change in protein function or regulation…”
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Changes in anticoagulant and antiplatelet drug supply at US hospitals before and during the COVID-19 pandemic (2018-2021) by Wong, Paul J, Mosley, Scott A, Ng, Tien M H, Shooshtari, Andrew, Alexander, G Caleb, Qato, Dima M

“…Abstract Purpose Antithrombotic agents have a role in coronavirus disease 2019 (COVID-19) treatment, but the pandemic disrupted medication supply. This study…”
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Medication reconciliation to support pharmacogenomics implementation by Mosley, Scott A, Pevnick, Joshua M

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CYP2D6‐guided opioid therapy for adults with cancer pain: A randomized implementation clinical trial by Mosley, Scott A., Cicali, Emily, Del Cueto, Alex, Portman, Diane G., Donovan, Kristine A., Gong, Yan, Langaee, Taimour, Gopalan, Priya, Schmit, Jessica, Starr, Jason S., Silver, Natalie, Chang, Young D., Rajasekhara, Sahana, Smith, Joshua E., Soares, Heloisa P., Clare‐Salzler, Michael, Starostik, Petr, George, Thomas J., McLeod, Howard L., Fillingim, Roger B., Hicks, J. Kevin, Cavallari, Larisa H.

“…Introduction The CYP2D6 enzyme metabolizes opioids commonly prescribed for cancer‐related pain, and CYP2D6 polymorphisms may contribute to variability in…”
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Examination of Metoprolol Pharmacokinetics and Pharmacodynamics Across CYP2D6 Genotype‐Derived Activity Scores by Thomas, Cameron D., Mosley, Scott A., Kim, Sarah, Lingineni, Karthik, El Rouby, Nihal, Langaee, Taimour Y., Gong, Yan, Wang, Danxin, Schmidt, Siegfried O., Binkley, Philip F., Estores, David S., Feng, Kairui, Kim, Hyewon, Kinjo, Minori, Li, Zhichuan, Fang, Lanyan, Chapman, Arlene B., Cooper-DeHoff, Rhonda M., Gums, John G., Hamadeh, Issam S., Zhao, Liang, Schmidt, Stephan, Frye, Reginald F., Johnson, Julie A., Cavallari, Larisa H.

“…Recent CYP2D6 phenotype standardization efforts by CYP2D6 activity score (AS) are based on limited pharmacokinetic (PK) and pharmacodynamic (PD) data. Using…”
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Design and rational for the precision medicine guided treatment for cancer pain pragmatic clinical trial by Mosley, Scott A., Hicks, J.Kevin, Portman, Diane G., Donovan, Kristine A., Gopalan, Priya, Schmit, Jessica, Starr, Jason, Silver, Natalie, Gong, Yan, Langaee, Taimour, Clare-Salzler, Michael, Starostik, Petr, Chang, Young D., Rajasekhara, Sahana, Smith, Joshua E., Soares, Heloisa P., George, Thomas J., McLeod, Howard L., Cavallari, Larisa H.

“…Pain is one of the most burdensome symptoms associated with cancer and its treatment, and opioids are the cornerstone of pain management. Opioid therapy is…”
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Evaluation of Liposomal Curcumin Cytochrome P450 Metabolism by MACH, Claire M, JING HONG CHEN, MOSLEY, Scott A, KURZROCK, Razelle, SMITH, Judith A

“…Curcumin (diferuloylmethane) is a commonly used spice and nutritional supplement that has demonstrated potential anti-tumor and anti-inflammatory activity…”
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Ligand-specific pharmacogenetic effects of nonsynonymous mutations by Morningstar-Kywi, Noam, Haworth, Ian S., Mosley, Scott A.

“…In pharmacogenomics, variable receptor phenotypes, resulting from genetic polymorphisms, are often described as a change in protein function or regulation…”
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Decoding pharmacogenomic test interpretation and application to patient care by Donnelly, Roseann S., Cavallari, Larisa H., McCune, Jeannine S., Trofe‐Clark, Jennifer, Formea, Christine M., Hoffecker, Glenda, Csere, Molly M., Anderson, Keri C., Bhat, Shubha, Mosley, Scott A., Ma, Qing, Ferdock, Ariel, Hoffman, James M., Hicks, J. Kevin, Caudle, Kelly E.

“…Pharmacogenomics is a growing area of medicine, and pharmacists across clinical practice settings have the opportunity to individualize medication selection…”
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Guidelines for therapeutic interchange—2022 by Welty, Timothy E., Hilaire, Michelle L., Frantzen, Leah M., Achey, Thomas S., Minze, Molly G., Japs, Kelsey L., Elliott, Amber N., Brasher, Cynthia A., May, Dianne W., Mosley, Scott A., Johnson, Corinne G., Grimm, Derek L., Huffman, Sara

“…The American College of Clinical Pharmacy (ACCP) Board of Regents charged the 2020 to 2021 Publications Committee to review and revise the 2004 ACCP guideline…”
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