Search Results - "Moshayedi, Natalie"
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Phase I trial of Bermekimab with nanoliposomal irinotecan and 5-fluorouracil/folinic acid in advanced pancreatic ductal adenocarcinoma
Published in Scientific reports (02-09-2022)“…In this phase I dose-escalation trial, we assess the maximum tolerated dose (MTD) of Bermekimab in combination with Nanoliposomal Irinotecan (Nal-Iri) and…”
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Primary survival outcomes between metastatic sites in ovarian cancer
Published in Gynecologic oncology (01-11-2024)Get full text
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Race, sex, age, and geographic disparities in pancreatic cancer incidence
Published in Journal of clinical oncology (01-02-2022)“…Abstract only 520 Background: Pancreatic cancer has a poor prognosis and a 5-year survival rate of 10%. A population-risk level analysis of pancreatic cancer…”
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Retrospective study of survival outcomes in patients with hereditary pathogenic and variants of unknown significance mutations in pancreatic adenocarcinoma
Published in Journal of clinical oncology (01-02-2022)“…Abstract only 616 Background: Since 2019, all patients with pancreatic adenocarcinoma (PDAC) are recommended to undergo germline testing per the National…”
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A phase I study of first-line L-glutamine (Gln) with gemcitabine (gem) and nab-paclitaxel (nab-p) in advanced pancreatic cancer (GlutaPanc)
Published in Journal of clinical oncology (01-02-2022)“…Abstract only TPS636 Background: Cytotoxic chemotherapy remains the preferred first-line treatment for advanced or unresectable pancreatic cancer with…”
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Fecal microbiome composition in pancreatic cancer cachexia and response to nutrition support
Published in Journal of clinical oncology (20-05-2021)“…Abstract only 4129 Background: Pancreatic ductal adenocarcinoma (PDAC) carries a poor prognosis with a 5-year survival rate of 10.0%. Previous studies in stool…”
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Metabolomics in advanced pancreatic cancer (PC) patients (pts) achieving weight stability on enteral feeding for cachexia
Published in Journal of clinical oncology (01-06-2022)“…e16291 Background: We previously showed that enteral feeding was associated with weight stability and compositional changes in the gut microbiome with…”
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Plasma metabolomics to predict chemotherapy (CTX) response in advanced pancreatic cancer (PC) patients (pts) on enteral feeding for cachexia
Published in Journal of clinical oncology (01-02-2022)“…Abstract only 600 Background: We evaluated the potential of plasma metabolites as predictors of response to CTX in a prospective cohort of pts who received…”
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Hyaluronan heterogeneity in pancreatic ductal adenocarcinoma, primary tumors, and sites of metastasis
Published in Journal of clinical oncology (20-05-2021)“…Abstract only e16231 Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers with an estimated five-year survival rate of…”
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Exceptional Response to Erdafitinib in FGFR2-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Published in Journal of the National Comprehensive Cancer Network (01-10-2022)“…Despite advances in cancer therapeutics, pancreatic ductal adenocarcinoma (PDAC) remains among the deadliest malignancies, with a poor prognosis at time of…”
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Impact of site-specific metastases on survival outcomes in pancreatic adenocarcinoma (PDAC) patients: A national analysis
Published in Journal of clinical oncology (01-06-2022)“…e16270 Background: PDAC is the third most fatal cancer, where most patients present with metastases at diagnosis. Previous studies, including a retrospective…”
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Genomic correlates of response to capecitabine and temozolomide (CAPTEM) in pancreatic neuroendocrine tumors
Published in Journal of clinical oncology (01-06-2022)“…4124 Background: Despite the frequent use of capecitabine and temozolomide (CAPTEM) to treat metastatic, well-differentiated pancreatic neuroendocrine tumors…”
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Mo1144 DECREASED EXPRESSION OF HISTONE DEACETYLASE 4 (HDAC4) AND YES-ASSOCIATED PROTEIN 1 (YAP) IN IMMUNOSUPPRESSIVE MYELOID CELLS AND FIBROBLASTS IN THE TME OF PANCREATIC DUCTAL ADENOCARCINOMA (PDAC) IS ASSOCIATED WITH EXCEPTIONAL CLINICAL RESPONSE
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2023)Get full text
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Real-world clinical outcomes and molecular features of lung-specific and liver-specific metastases in pancreatic ductal adenocarcinoma (PDAC)
Published in Journal of clinical oncology (01-02-2022)“…Abstract only 532 Background: PDAC remains one of the most lethal malignancies following metastatic presentation, typically to the liver or lung. Previous…”
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Hyaluronan heterogeneity in pancreatic ductal adenocarcinoma: Primary tumors compared to sites of metastasis
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-01-2022)“…Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers with poor survival. The dense desmoplastic stroma in PDAC contributes to…”
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Plasma Metabolomics Predicts Chemotherapy Response in Advanced Pancreatic Cancer
Published in Cancers (01-06-2023)“…Pancreatic cancer (PC) is one of the deadliest cancers. Developing biomarkers for chemotherapeutic response prediction is crucial for improving the dismal…”
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Tumor hyaluronan as a novel biomarker in non-small cell lung cancer: A retrospective study
Published in Oncotarget (02-11-2022)“…Hyaluronan (HA) accumulation is associated with tumorigenesis and aggressive tumor behavior. We investigated the biomarker potential of HA in non-small cell…”
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Gut microbiome and pancreatic cancer cachexia: An evolving relationship
Published in World journal of gastrointestinal oncology (15-07-2022)“…Nearly 80% of patients with pancreatic ductal adenocarcinoma (PDAC) develop cachexia along their disease course. Cachexia is characterized by progressive…”
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A Comparison of Clinicopathologic Outcomes Across Neoadjuvant and Adjuvant Treatment Modalities in Resectable Gastric Cancer
Published in JAMA network open (01-12-2021)“…Treatment of resectable gastric cancer (RGC) uses a multimodal approach, including surgical treatment and chemotherapy with or without radiation therapy, and…”
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