Search Results - "Moseley, Janae"

Magnesium sulfate treatment reverses seizure susceptibility and decreases neuroinflammation in a rat model of severe preeclampsia by Johnson, Abbie Chapman, Tremble, Sarah M, Chan, Siu-Lung, Moseley, Janae, LaMarca, Babbette, Nagle, Keith J, Cipolla, Marilyn J

“…Eclampsia, defined as unexplained seizure in a woman with preeclampsia, is a life-threatening complication of pregnancy with unclear etiology. Magnesium…”
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Progesterone blunts vascular endothelial cell secretion of endothelin-1 in response to placental ischemia by Kiprono, Luissa V., DO, Wallace, Kedra, PhD, Moseley, Janae, BS, Martin, James, MD, LaMarca, Babbette, PhD

“…Objective Preeclampsia (PE) is associated with hypertension and elevated endothelin (ET-1), an indicator of endothelial cell activation and dysfunction…”
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IL-10 supplementation increases Tregs and decreases hypertension in the RUPP rat model of preeclampsia by Harmon, Ashlyn, Cornelius, Denise, Amaral, Lorena, Paige, Adrienne, Herse, Florian, Ibrahim, Tarek, Wallukat, Gerd, Faulkner, Jessica, Moseley, Janae, Dechend, Ralf, LaMarca, Babbette

“…Objective: The reduced uterine perfusion pressure (RUPP) rat model of preeclampsia was used to determine the effects of added interleukin-10 (IL-10) on Tregs…”
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Progesterone supplementation attenuates hypertension and the autoantibody to the angiotensin II type I receptor in response to elevated interleukin-6 during pregnancy by Amaral, Lorena M., PhD, Kiprono, Luissa, DO, Cornelius, Denise C., PhD, Shoemaker, Carrie, BS, Wallace, Kedra, PhD, Moseley, Janae, BS, Wallukat, Gerd, PhD, Martin, James N., MD, Dechend, Ralf, MD, LaMarca, Babbette, PhD

“…Objective Preeclampsia is a multisystem disorder recognized as hypertension with proteinuria developing >20 weeks' gestation. Preeclampsia is associated with…”
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Administration of Interleukin-17 Soluble Receptor C Suppresses TH17 Cells, Oxidative Stress, and Hypertension in Response to Placental Ischemia During Pregnancy by CORNELIUS, Denise C, HOGG, James P, SCOTT, Jeremy, WALLACE, Kedra, HERSE, Florian, MOSELEY, Janae, WALLUKAT, Gerd, DECHEND, Ralf, LAMARCA, Babbette

“…Preeclampsia, new onset hypertension with proteinuria during pregnancy, is associated with chronic inflammation and placental oxidative stress (ROS). Chronic…”
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An increased population of regulatory T cells improves the pathophysiology of placental ischemia in a rat model of preeclampsia by Cornelius, Denise C, Amaral, Lorena M, Harmon, Ashlyn, Wallace, Kedra, Thomas, Alexia J, Campbell, Nathan, Scott, Jeremy, Herse, Florian, Haase, Nadine, Moseley, Janae, Wallukat, Gerd, Dechend, Ralf, LaMarca, Babbette

“…The reduced uterine perfusion pressure (RUPP) rat model of preeclampsia exhibits much of the pathology characterizing this disease, such as hypertension,…”
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17-Hydroxyprogesterone Caproate Significantly Improves Clinical Characteristics of Preeclampsia in the Reduced Uterine Perfusion Pressure Rat Model by Amaral, Lorena M, Cornelius, Denise C, Harmon, Ashlyn, Moseley, Janae, Martin, James N, LaMarca, Babbette

“…Preeclampsia is characterized by increased uterine artery resistance index, chronic immune activation, and decreased circulating nitric oxide levels…”
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Endothelin-1, Oxidative Stress, and Endogenous Angiotensin II: Mechanisms of Angiotensin II Type I Receptor Autoantibody–Enhanced Renal and Blood Pressure Response During Pregnancy by Brewer, Justin, Liu, Ruisheng, Lu, Yan, Scott, Jeremy, Wallace, Kedra, Wallukat, Gerd, Moseley, Janae, Herse, Florian, Dechend, Ralf, Martin, James N, LaMarca, Babbette

“…Hypertension during preeclampsia is associated with increased maternal vascular sensitivity to angiotensin II (ANGII). This study was designed to determine…”
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CD4+ T cells are important mediators of oxidative stress that cause hypertension in response to placental ischemia by Wallace, Kedra, Cornelius, Denise C, Scott, Jeremy, Heath, Judith, Moseley, Janae, Chatman, Krystal, LaMarca, Babbette

“…Preeclampsia is associated with oxidative stress, which is suspected to play a role in hypertension, placental ischemia, and fetal demise associated with the…”
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Blockade Of The ET A Receptor In An Animal Model Of HELLP Syndrome by Wallace, Kedra, Spencer, Shauna, Kyle, Patrick, Moseley, Janae, Morris, Rachael

“…Abstract only Women with hypertensive forms of pregnancy such as hemolysis‐elevated liver enzymes‐low platelet‐syndrome have increased circulating levels of…”
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Inhibition of 20‐HETE Synthesis Attenuates Elevations in Blood Pressure and Uterine Artery Resistance Index in the RUPP Rat Model of Preeclampsia by Faulkner, Jessica, Murphy, Sydney, Lee, Nicole, Moseley, Janae, LaMarca, Babbette

“…Abstract only…”
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Specific inhibition of AT1‐AAs by direct binding improves maternal and fetal outcome in response to placental ischemia during pregnancy: emphasizing the importance of novel drug development in the treatment of preeclampsia (860.15) by Moseley, Janae, Castillo, Javier, Amaral, Lorena, Cornelius, Denise, LaMarca, Babbette

“…Preeclampsia, (PE) hypertension with proteinuria during pregnancy, is associated with antibodies that activate the angiotensin II receptor (AT1‐AA). Infusion…”
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Enodthelin 1 is elevated in plasma and explants from patients having uterine leiomyomas by Wallace, Kedra, Chatman, Krystal, Porter, Justin, Scott, Jeremy, Johnson, Venessia, Moseley, Janae, LaMarca, Babbette

“…To determine a role for endothelin (ET) in progression of uterine fibroids. An in vitro model of fibroid and myometrium cultivation. A total of 32 women…”
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Activating autoantibodies to the angiotensin II type I receptor play an important role in mediating hypertension in response to adoptive transfer of CD4+ T lymphocytes from placental ischemic rats by Novotny, Sarah Richards, Wallace, Kedra, Heath, Judith, Moseley, Janae, Dhillon, Pushpinder, Weimer, Abram, Wallukat, Gerd, Herse, Florian, Wenzel, Katrin, Martin, Jr, James N, Dechend, Ralf, Lamarca, Babbette

“…Hypertension in rats with chronic placental ischemia (reduced uterine perfusion pressure, RUPP) is associated with elevated inflammatory cytokines, agonistic…”
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Hypertension in response to CD4(+) T cells from reduced uterine perfusion pregnant rats is associated with activation of the endothelin-1 system by Wallace, Kedra, Novotny, Sarah, Heath, Judith, Moseley, Janae, Martin, Jr, James N, Owens, Michelle Y, LaMarca, Babbette

“…We have shown that adoptive transfer of CD4(+) T cells from placental ischemia (reduction in uteroplacental perfusion, RUPP) rats causes hypertension and…”
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Abstract 272: Reduced Uterine Perfusion Pressure Stimulated T-helper 17 Cells Cause Hypertension during Pregnancy by Cornelius, Denise C, Wallace, Kedra, Moseley, Janae, LaMarca, Babbette

“…Abstract only Preeclampsia (PE), new onset hypertension with proteinuria during pregnancy, is associated with chronic inflammation and an imbalance among…”
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Serelaxin Improves Blood Pressure and Uterine Artery Resistance in the Reduced Uterine Perfusion Pressure (RUPP) Rat Model of Preeclampsia by Amaral, Lorena, Santiago‐font, Jose, Gillis, Ellen, Moseley, Janae, Sasser, Jennifer, LaMarca, Babbette

“…Abstract only…”
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Placental Ischemia‐Induced T H 17 Cells Mediate the Pathophysiology Associated with Preeclampsia by Cornelius, Denise, Wallace, Kedra, Amaral, Lorena, Scott, Jeremy, Campbell, Nathan, Thomas, Alexia, Moseley, Janae, LaMarca, Babbette

“…Abstract only Preeclampsia (PE) is associated with hypertension, inflammation, intrauterine growth restriction (IUGR), increased CD4 + T Helper 17 cells (T H…”
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T Cell‐Dependent B Cell Activation Mediates Pathophysiology in Reponse to CD4 + T Cells from Reduced Uterine Perfusion Pregnant Rats by Cornelius, Denise, Castillo, Javier, Amaral, Lorena, Wallace, Kedra, Moseley, Janae, LaMarca, Babbette

“…Abstract only…”
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Early Administration of 17‐Hydroxyprogesterone Caproate to Reduced Uterine Perfusion Pressure (RUPP) Rat Model of Preeclampsia Improves Inflammation, Uterine artery Vasoconstriction and Blood Pressure During Pregnancy by Amaral, Lorena, Faulkner, Jessica, Cornelius, Denise, Moseley, Janae, Martin, James, LaMarca, Babbette

“…Abstract only…”
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