Search Results - "Mosa, Rebamang A."

Two Triterpenoids, ARM-2 and RA-5, From Protorhus longifolia Exhibit the Potential to Modulate Lipolysis and Lipogenesis in Cultured 3T3-L1 Adipocytes by Ndlovu, Musawenkosi, Serem, June C, Bester, Megan J, Apostolides, Zeno, Opoku, Andrew R, Mosa, Rebamang A

“…Triterpenoids have been identified as potential novel lipid-lowering drugs for the treatment of hypertriglyceridemia. This study investigated the potential…”
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Isolation and Characterization of Potential Lignin Peroxidase-Producing Bacteria from Compost Samples at Richards Bay (South Africa) by Dube, Sindiswa L, Osunsanmi, Foluso O, Ngcobo, Bongekile P, Mkhwanazi, Londiwe B, Jobe, Zanele Z, Aruleba, Raphael T, Mosa, Rebamang A, Opoku, Andrew R

“…Lignin recalcitrance is a key issue in producing value-added products from lignocellulose biomass. biodegradable lignin-modifying enzymes-producing bacteria…”
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In Vitro Antioxidant and In Silico Evaluation of the Anti-β-Lactamase Potential of the Extracts of Cylindrospermum alatosporum NR125682 and Loriellopsis cavenicola NR117881 by Ikhane, Albert O, Sithole, Siphesihle Z, Cele, Nkosinathi D, Osunsanmi, Foluso O, Mosa, Rebamang A, Opoku, Andrew R

“…Cyanobacteria in recent times have been touted to be a suitable source for the discovery of novel compounds, including antioxidants and antibiotics, due to…”
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A Lanosteryl Triterpene from Protorhus longifolia Improves Glucose Tolerance and Pancreatic Beta Cell Ultrastructure in Type 2 Diabetic Rats by Mabhida, Sihle E, Mosa, Rebamang A, Penduka, Dambudzo, Osunsanmi, Foluso O, Dludla, Phiwayinkosi V, Djarova, Tryana G, Opoku, Andy R

“…Type 2 diabetes remains one of the leading causes of death worldwide. Persistent hyperglycemia within a diabetic state is implicated in the generation of…”
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An In Vitro Study on the Combination Effect of Metformin and N-Acetyl Cysteine against Hyperglycaemia-Induced Cardiac Damage by Johnson, Rabia, Sangweni, Nonhlakanipho F, Mabhida, Sihle E, Dludla, Phiwayinkosi V, Mabasa, Lawrence, Riedel, Sylvia, Chapman, Charna, Mosa, Rebamang A, Kappo, Abidemi P, Louw, Johan, Muller, Christo J F

“…Chronic hyperglycaemia is a major risk factor for diabetes-induced cardiovascular dysfunction. In a hyperglycaemic state, excess production of reactive oxygen…”
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In vivo antihyperglycemic activity of a lanosteryl triterpene from Protorhus longifolia by Mosa, Rebamang A, Cele, Nkosinathi D, Mabhida, Sihle E, Shabalala, Samkelisiwe C, Penduka, Dambudzo, Opoku, Andy R

“…Control of postprandial hyperglycemia is crucial in the management of diabetes mellitus. Despite the use of the current hypoglycemic drugs, incidence of…”
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Triterpenoids from Protorhus longifolia Exhibit Hypocholesterolemic Potential via Regulation of Cholesterol Biosynthesis and Stimulation of Low-Density Lipoprotein Uptake in HepG2 Cells by Ndlovu, Musawenkosi, Serem, June C., Selepe, Mamoalosi A., Opoku, Andrew R., Bester, Megan J., Apostolides, Zeno, Mosa, Rebamang A.

“…The increasing incidence of hypercholesterolemia-related diseases even in the presence of the currently available cholesterol-lowering drugs indicates a need…”
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Potential Impact of the Multi-Target Drug Approach in the Treatment of Some Complex Diseases by Makhoba, Xolani H, Viegas, Jr., Claudio, Mosa, Rebamang A, Viegas, Flavia P.D, Pooe, Ofentse J

“…It is essential to acknowledge the efforts made thus far to manage or eliminate various disease burden faced by humankind. However, the rising global trends of…”
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Protective effect of triterpenes against diabetes-induced β-cell damage: An overview of in vitro and in vivo studies by Mabhida, Sihle E., Dludla, Phiwayinkosi V., Johnson, Rabia, Ndlovu, Musawenkosi, Louw, Johan, Opoku, Andy R., Mosa, Rebamang A.

“…Triterpenes display a strong potential to ameliorate diabetes induced β-cell damage through the modulation of several genes and proteins involved in insulin…”
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In silico and in vitro assessment of the anti-β-amyloid aggregation and anti-cholinesterase activities of Ptaeroxylon obliquum and Bauhinia bowkeri extracts by Ojo, Michael C., Mosa, Rebamang A., Osunsanmi, Foluso O., Revaprasadu, Neerish, Opoku, Andy R.

“…[Display omitted] Alzheimer’s disease (AD) is the most common form of dementia and dementia constitutes the fifth leading cause of mortality across the globe…”
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The triterpene, methyl-3β-hydroxylanosta-9,24-dien-21-oate (RA3), attenuates high glucose-induced oxidative damage and apoptosis by improving energy metabolism by Sangweni, Nonhlakanipho F., Mosa, Rebamang A., Dludla, Phiwayinkosi V., Kappo, Abidemi P., Opoku, Andy R., Muller, Christo J.F., Johnson, Rabia

“…Hyperglycemia-induced cardiovascular dysfunction has been linked to oxidative stress and accelerated apoptosis in the diabetic myocardium. While there is…”
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Phytochemical Profiling and Isolation of Bioactive Compounds from Leucosidea sericea (Rosaceae) by Ramabulana, Tshifhiwa, Ndlovu, Musawenkosi, Mosa, Rebamang A, Sonopo, Molahlehi S, Selepe, Mamoalosi A

“…In the study, ultraperformance liquid chromatography–quadrupole time-of-flight–mass spectrometry analysis of Leucosidea sericea leaf and stem extracts led to…”
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Lanosteryl triterpenes from Protorhus longifolia as a cardioprotective agent: a mini review by Sangweni, Nonhlakanipho F., Dludla, Phiwayinkosi V., Mosa, Rebamang A., Kappo, Abidemi P., Opoku, Andy, Muller, Christo J. F., Johnson, Rabia

“…The epidemic of cardiovascular diseases is a global phenomenon that is exaggerated by the growing prevalence of diabetes mellitus. Coronary artery disease and…”
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In vitro and in vivo antioxidant potentials of the methanolic crude extract from Inula glomerata Oliv. & Hiern (Asteraceae) and Salacia kraussii (Harv.) Harv (Celastraceae) by Ojo, Michael C, Osunsanmi, Foluso O, Cele, Nkosinathi D, Zharare, Godfrey E, Mosa, Rebamang A, Opoku, Andy R

“…Reactive oxygen species are implicated in multiple pathological conditions including erectile dysfunction. This study evaluated the in vitro and in vivo…”
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Cardioprotective potential of a lanosteryl triterpene from Protorhus longifolia by Mosa, Rebamang A., Hlophe, Nomadlozi B., Ngema, Namani T., Penduka, Dambudzo, Lawal, Oladipupo A., Opoku, Andy R.

“…Context: The current rapid increase in the incidence of cardiovascular events indicates a need for the discovery of more effective cardioprotective agents…”
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In vitro antihyperlipidemic potential of triterpenes from stem bark of Protorhus longifolia by Mosa, Rebamang A, Naidoo, Javan J, Nkomo, Fezile S, Mazibuko, Sithandiwe E, Muller, Christo J F, Opoku, Andy R

“…Two lanostane triterpenes, 3β-hydroxylanosta-9,24-dien-21-oic acid (1) and methyl-3β-hydroxylanosta-9,24-dien-21-oate (2), were isolated from the stem bark of…”
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In vivo anti-hyperlipidemic activity of the triterpene from the stem bark of Protorhus longifolia (Benrh) Engl by Machaba, Kgothatso E, Cobongela, Sinazo Z Z, Mosa, Rebamang A, Oladipupo, Lawal A, Djarova, Trayana G, Opoku, Andy R

“…Hyperlipidemia, a metabolic disorder of lipids, is a well known risk factor of cardiovascular events and metabolic syndrome. In this study, the in vivo…”
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Anti-platelet aggregation of mixtures of betulinic oleanolic and maslinic acids and derivatives from medicinal plants by Osunsanmi, Foluso O, Oyinloye, Babatunji E, Mosa, Rebamang A, Ikhile, Monisola I, Ngila, J. Catherine, Shode, Francis O, Singh, M, Opoku, Andy R

“…Purpose: To evaluate the antiplatelet aggregation and cytotoxic potential of betulinic acid (BA), oleanolic acid (OA), maslinic acid (MA) and their derivatives…”
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In Vitro Antioxidant and In Silico Evaluation of the Anti-β-Lactamase Potential of the Extracts of ICylindrospermum alatosporum/I NR125682 and ILoriellopsis cavenicola/I NR117881 by Ikhane, Albert O, Sithole, Siphesihle Z, Cele, Nkosinathi D, Osunsanmi, Foluso O, Mosa, Rebamang A, Opoku, Andrew R

“…Cyanobacteria in recent times have been touted to be a suitable source for the discovery of novel compounds, including antioxidants and antibiotics, due to…”
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Triterpenes from the stem bark of Protorhus longifolia exhibit anti-platelet aggregation activity by Rebamang A. Mosa

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