Search Results - "Morton, Penny E"

Targeted fluorescence lifetime probes reveal responsive organelle viscosity and membrane fluidity by Steinmark, Ida Emilie, James, Arjuna L, Chung, Pei-Hua, Morton, Penny E, Parsons, Maddy, Dreiss, Cécile A, Lorenz, Christian D, Yahioglu, Gokhan, Suhling, Klaus

“…The only way to visually observe cellular viscosity, which can greatly influence biological reactions and has been linked to several human diseases, is through…”
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Folliculin directs the formation of a Rab34-RILP complex to control the nutrient-dependent dynamic distribution of lysosomes by Starling, Georgina P, Yip, Yan Y, Sanger, Anneri, Morton, Penny E, Eden, Emily R, Dodding, Mark P

“…The spatial distribution of lysosomes is important for their function and is, in part, controlled by cellular nutrient status. Here, we show that the lysosome…”
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Epithelial Inflammation Resulting from an Inherited Loss-of-Function Mutation in EGFR by Campbell, Patrick, Morton, Penny E., Takeichi, Takuya, Salam, Amr, Roberts, Nerys, Proudfoot, Laura E., Mellerio, Jemima E., Aminu, Kingi, Wellington, Cheryl, Patil, Sachin N., Akiyama, Masashi, Liu, Lu, McMillan, James R., Aristodemou, Sophia, Ishida-Yamamoto, Akemi, Abdul-Wahab, Alya, Petrof, Gabriela, Fong, Kenneth, Harnchoowong, Sarawin, Stone, Kristina L., Harper, John I., Irwin McLean, W.H., Simpson, Michael A., Parsons, Maddy, McGrath, John A.

“…Epidermal growth factor receptor (EGFR) signaling is fundamentally important for tissue homeostasis through EGFR/ligand interactions that stimulate numerous…”
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CAR modulates E-cadherin dynamics in the presence of adenovirus type 5 by Hussain, Fawziyah, Morton, Penny E, Snippe, Marjolein, Sullivan, Janis, Farmer, Charlotte, Martin-Fernandez, Marisa L, Parsons, Maddy, Santis, George

“…Adenovirus (Ad) serotype 5 (Ad5) fiber competitively binds to the coxsackievirus and Ad receptor (CAR) to attach Ad5 to target cells and also disrupts cell…”
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Dissecting cell adhesion architecture using advanced imaging techniques by Morton, Penny E., Parsons, Maddy

“…Cell adhesion to extracellular matrix proteins or to other cells is essential for the control of embryonic development, tissue integrity, immune function and…”
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Transmigration of Leukocytes Across Epithelial Monolayers by Morton, Penny E, Parsons, Maddy

“…Migration of leukocytes through epithelial monolayers represents an essential step in the generation of an inflammatory response and is often seen in…”
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TNFR1 membrane reorganization promotes distinct modes of TNFα signaling by Morton, Penny E, Perrin, Camille, Levitt, James, Matthews, Daniel R, Marsh, Richard J, Pike, Rosemary, McMillan, David, Maloney, Alison, Poland, Simon, Ameer-Beg, Simon, Parsons, Maddy

“…Signaling by the ubiquitously expressed tumor necrosis factor receptor 1 (TNFR1) after ligand binding plays an essential role in determining whether cells…”
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CAR regulates epithelial cell junction stability through control of E-cadherin trafficking by Morton, Penny E., Hicks, Alexander, Nastos, Theodoros, Santis, George, Parsons, Maddy

“…CAR (Coxsackie and Adenovirus Receptor) is the primary docking receptor for typeB coxsackie viruses and subgroup C adenoviruses. CAR is a member of the JAM…”
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TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers by Morton, Penny E., Hicks, Alexander, Ortiz-Zapater, Elena, Raghavan, Swetavalli, Pike, Rosemary, Noble, Alistair, Woodfin, Abigail, Jenkins, Gisli, Rayner, Emma, Santis, George, Parsons, Maddy

“…Trans-epithelial migration (TEpM) of leukocytes during inflammation requires engagement with receptors expressed on the basolateral surface of the epithelium…”
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αvβ3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration by Worth, Daniel C, Hodivala-Dilke, Kairbaan, Robinson, Stephen D, King, Samantha J, Morton, Penny E, Gertler, Frank B, Humphries, Martin J, Parsons, Maddy

“…Integrins are fundamental to the control of protrusion and motility in adherent cells. However, the mechanisms by which specific members of this receptor…”
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Time-resolved multifocal multiphoton microscope for high speed FRET imaging in vivo by Poland, Simon P, Krstajić, Nikola, Coelho, Simao, Tyndall, David, Walker, Richard J, Devauges, Viviane, Morton, Penny E, Nicholas, Nicole S, Richardson, Justin, Li, David Day-Uei, Suhling, Klaus, Wells, Claire M, Parsons, Maddy, Henderson, Robert K, Ameer-Beg, Simon M

“…Imaging the spatiotemporal interaction of proteins in vivo is essential to understanding the complexities of biological systems. The highest accuracy…”
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Disruption of the Coxsackievirus and Adenovirus Receptor-Homodimeric Interaction Triggers Lipid Microdomain- and Dynamin-dependent Endocytosis and Lysosomal Targeting by Salinas, Sara, Zussy, Charleine, Loustalot, Fabien, Henaff, Daniel, Menendez, Guillermo, Morton, Penny E., Parsons, Maddy, Schiavo, Giampietro, Kremer, Eric J.

“…The coxsackievirus and adenovirus receptor (CAR) serves as a docking factor for some adenovirus (AdV) types and group B coxsackieviruses. Its role in AdV…”
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Coxsackie adenovirus receptor (CAR) regulates integrin function through activation of p44/42 MAPK by Farmer, Charlotte, Morton, Penny E., Snippe, Marjolein, Santis, George, Parsons, Maddy

“…The coxsackie B virus and adenovirus receptor (CAR) is an attachment receptor for Adenovirus serotype 5 (Ad5) and in many cell types forms homodimers with…”
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Simultaneous FRAP, FLIM and FAIM for measurements of protein mobility and interaction in living cells by Levitt, James A, Morton, Penny E, Fruhwirth, Gilbert O, Santis, George, Chung, Pei-Hua, Parsons, Maddy, Suhling, Klaus

“…We present a novel integrated multimodal fluorescence microscopy technique for simultaneous fluorescence recovery after photobleaching (FRAP), fluorescence…”
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Prostate-derived Sterile 20-like Kinases (PSKs/TAOKs) Are Activated in Mitosis and Contribute to Mitotic Cell Rounding and Spindle Positioning by Wojtala, Rachael L., Tavares, Ignatius A., Morton, Penny E., Valderrama, Ferran, Thomas, N. Shaun B., Morris, Jonathan D.H.

“…Prostate-derived sterile 20-like kinases (PSKs) 1-α, 1-β, and 2 are members of the germinal-center kinase-like sterile 20 family of kinases. Previous work has…”
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Measuring FRET using time-resolved FLIM by Morton, Penny E, Parsons, Maddy

“…Cell migration is a process that is controlled by the formation and correct localization of protein complexes and by post-translational modification of…”
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[alpha]v[beta]3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration by Worth, Daniel C, Hodivala-Dilke, Kairbaan, Robinson, Stephen D, King, Samantha J, Morton, Penny E, Gertler, Frank B, Humphries, Martin J, Parsons, Maddy

“…Integrins are fundamental to the control of protrusion and motility in adherent cells. However, the mechanisms by which specific members of this receptor…”
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TNF[alpha] promotes CAR-dependent migration of leukocytes across epithelial monolayers by Morton, Penny E, Hicks, Alexander, Ortiz-zapater, Elena, Raghavan, Swetavalli, Pike, Rosemary, Noble, Alistair, Woodfin, Abigail, Jenkins, Gisli, Rayner, Emma, Santis, George, Parsons, Maddy

“…Trans-epithelial migration (TEpM) of leukocytes during inflammation requires engagement with receptors expressed on the basolateral surface of the epithelium…”
Get full text

Alpha v beta3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration by Worth, Daniel C, Hodivala-Dilke, Kairbaan, Robinson, Stephen D, King, Samantha J, Morton, Penny E, Gertler, Frank B, Humphries, Martin J, Parsons, Maddy

“…Integrins are fundamental to the control of protrusion and motility in adherent cells. However, the mechanisms by which specific members of this receptor…”
Get full text