Search Results - "Morton, Gerard"

Preliminary Toxicity Analysis of 3-Dimensional Conformal Radiation Therapy Versus Intensity Modulated Radiation Therapy on the High-Dose Arm of the Radiation Therapy Oncology Group 0126 Prostate Cancer Trial by Michalski, Jeff M., MD, Yan, Yan, MD, MS, Watkins-Bruner, Deborah, PhD, Bosch, Walter R., DSc, Winter, Kathryn, MS, Galvin, James M., DSc, Bahary, Jean-Paul, MD, Morton, Gerard C., MB, Parliament, Matthew B., MD, Sandler, Howard M., MD

“…Purpose To give a preliminary report of clinical and treatment factors associated with toxicity in men receiving high-dose radiation therapy (RT) on a phase 3…”
Get full text

Androgen Suppression Combined with Elective Nodal and Dose Escalated Radiation Therapy (the ASCENDE-RT Trial): An Analysis of Survival Endpoints for a Randomized Trial Comparing a Low-Dose-Rate Brachytherapy Boost to a Dose-Escalated External Beam Boost for High- and Intermediate-risk Prostate Cancer by Morris, W. James, MD, FRCPC, Tyldesley, Scott, MD, FRCPC, Rodda, Sree, MBBS, MRCP, FRCR, Halperin, Ross, MD, FRCPC, Pai, Howard, MD, FRCPC, McKenzie, Michael, MD, FRCPC, Duncan, Graeme, MB, ChB, FRCPC, Morton, Gerard, MB, MRCPI, FRCPC, FFRRCSI, Hamm, Jeremy, MSC, Murray, Nevin, MD, FRCPC

“…Purpose To report the primary endpoint of biochemical progression-free survival (b-PFS) and secondary survival endpoints from ASCENDE-RT, a randomized trial…”
Get full text

Prostate high dose-rate brachytherapy as monotherapy for low and intermediate risk prostate cancer: Efficacy results from a randomized phase II clinical trial of one fraction of 19 Gy or two fractions of 13.5 Gy by Morton, Gerard, McGuffin, Merrylee, Chung, Hans T., Tseng, Chia-Lin, Helou, Joelle, Ravi, Ananth, Cheung, Patrick, Szumacher, Ewa, Liu, Stanley, Chu, William, Zhang, Liying, Mamedov, Alexandre, Loblaw, Andrew

“…•HDR monotherapy as 13.5 Gy × 2 is highly effective for low and intermediate risk prostate cancer.•Single fraction HDR monotherapy has high local failure rate…”
Get full text

The evolution of brachytherapy for prostate cancer by Zaorsky, Nicholas G., Davis, Brian J., Nguyen, Paul L., Showalter, Timothy N., Hoskin, Peter J., Yoshioka, Yasuo, Morton, Gerard C., Horwitz, Eric M.

“…Key Points Brachytherapy and brachytherapy boost with low-dose-rate brachytherapy (LDR-BT) or high-dose-rate (HDR)-BT can be used as first-line therapies in…”
Get full text

ASCENDE-RT: An Analysis of Treatment-Related Morbidity for a Randomized Trial Comparing a Low-Dose-Rate Brachytherapy Boost with a Dose-Escalated External Beam Boost for High- and Intermediate-Risk Prostate Cancer by Rodda, Sree, MBBS, MRCP, FRCR, Tyldesley, Scott, MD, FRCPC, Morris, W. James, MD, FRCPC, Keyes, Mira, MD, FRCPC, Halperin, Ross, MD, FRCPC, Pai, Howard, MD, FRCPC, McKenzie, Michael, MD, FRCPC, Duncan, Graeme, MB, ChB, FRCPC, Morton, Gerard, MB, MRCPI, FRCPC, FFRRCSI, Hamm, Jeremy, MSC, Murray, Nevin, MD, FRCPC

“…Purpose To report the genitourinary (GU) and gastrointestinal (GI) morbidity and erectile dysfunction in a randomized trial comparing 2 methods of dose…”
Get full text

High dose-rate brachytherapy in the treatment of prostate cancer by Mendez, Lucas C, Morton, Gerard C

“…High dose-rate (HDR) brachytherapy involves delivery of a high dose of radiation to the cancer with great sparing of surrounding organs at risk. Prostate…”
Get full text

High-dose-rate brachytherapy boost for prostate cancer: rationale and technique by Morton, Gerard C

“…High-dose-rate brachytherapy (HDR) is a method of conformal dose escalation to the prostate. It can be used as a local boost in combination with external beam…”
Get full text

Single Fraction High-Dose-Rate Brachytherapy: Too Good to Be True? by Morton, Gerard C., Hoskin, Peter J.

Get full text

A Prospective Phase 2 Trial of Transperineal Ultrasound-Guided Brachytherapy for Locally Recurrent Prostate Cancer After External Beam Radiation Therapy (NRG Oncology/RTOG-0526) by Crook, Juanita M., Zhang, Peixin, Pisansky, Thomas M., Trabulsi, Edouard J., Amin, Mahul B., Bice, William, Morton, Gerard, Pervez, Nadeem, Vigneault, Eric, Catton, Charles, Michalski, Jeff, Roach, Mack, Beyer, David, Jani, Ashesh, Horwitz, Eric, Donavanik, Viroon, Sandler, Howard

“…Only retrospective data are available for low-dose-rate (LDR) salvage prostate brachytherapy for local recurrence after external beam radiation therapy (EBRT)…”
Get full text

Dose-Escalated Radiation Alone or in Combination With Short-Term Total Androgen Suppression for Intermediate-Risk Prostate Cancer: Patient-Reported Outcomes From NRG/Radiation Therapy Oncology Group 0815 Randomized Trial by Movsas, Benjamin, Rodgers, Joseph P, Elshaikh, Mohamed A, Martinez, Alvaro A, Morton, Gerard C, Krauss, Daniel J, Yan, Di, Citrin, Deborah E, Hershatter, Bruce W, Michalski, Jeff M, Ellis, Rodney J, Kavadi, Vivek S, Gore, Elizabeth M, Gustafson, Gary S, Schulz, Craig A, Velker, Vikram M, Olson, Adam C, Cury, Fabio L, Papagikos, Michael A, Karrison, Theodore G, Sandler, Howard M, Bruner, Deborah W

“…To report patient-reported outcomes (PROs) of a phase III trial evaluating total androgen suppression (TAS) combined with dose-escalated radiation therapy (RT)…”
Get full text

American Brachytherapy Society consensus guidelines for high-dose-rate prostate brachytherapy by Yamada, Yoshiya, Rogers, Leland, Demanes, D. Jeffrey, Morton, Gerard, Prestidge, Bradley R, Pouliot, Jean, Cohen, Gil'ad N, Zaider, Marco, Ghilezan, Mihai, Hsu, I-Chow

“…Abstract Purpose A well-established body of literature supports the use of high-dose-rate (HDR) brachytherapy as definitive treatment for localized prostate…”
Get full text

Evaluation of a machine-learning algorithm for treatment planning in prostate Low-Dose-Rate brachytherapy by Nicolae, Alexandru, MSc, Morton, Gerard, MD, Chung, Hans, MD, Loblaw, Andrew, MD, Jain, Suneil, MB BCh PhD, Mitchell, Darren, MB BCh, Lu, Lin, BSc, Helou, Joelle, MD, Al-Hanaqta, Motasem, MD, Heath, Emily, PhD, Ravi, Ananth, PhD

“…Abstract Purpose This work presents the application of a machine learning (ML) algorithm to automatically generate high-quality, prostate Low-Dose-Rate (LDR)…”
Get full text

Potential applications of the quantitative susceptibility mapping (QSM) in MR-guided radiation therapy by Nosrati, Reyhaneh, Paudel, Moti, Ravi, Ananth, Pejovic-Milic, Ana, Morton, Gerard, Stanisz, Greg J

“…Magnetic resonance-guided radiation therapy (MR-GRT) offers great potential to improve radiation treatment outcomes by providing more accurate and…”
Get more information

MRI-based automated detection of implanted low dose rate (LDR) brachytherapy seeds using quantitative susceptibility mapping (QSM) and unsupervised machine learning (ML) by Nosrati, Reyhaneh, Soliman, Abraam, Safigholi, Habib, Hashemi, Masoud, Wronski, Matthew, Morton, Gerard, Pejović-Milić, Ana, Stanisz, Greg, Song, William Y.

“…•Quantitative Susceptibility Mapping generated positive contrast for brachytherapy seeds.•Seeds were differentiable from calcifications on magnetic…”
Get full text

Prostate high-dose-rate brachytherapy: Transrectal ultrasound based planning, a technical note by Morton, Gerard C.

Get full text

Single-Fraction High-Dose-Rate Brachytherapy and Hypofractionated External Beam Radiotherapy for Men With Intermediate-Risk Prostate Cancer: Analysis of Short- and Medium-Term Toxicity and Quality of Life by Morton, Gerard C., M.B., F.R.C.P.C, Loblaw, D. Andrew, M.D., M.Sc., F.R.C.P.C, Sankreacha, Raxa, M.Sc, Deabreu, Andrea, Zhang, Liying, Ph.D, Mamedov, Alexandre, Cheung, Patrick, M.D., F.R.C.P.C, Keller, Brian, Ph.D, Danjoux, Cyril, M.D., F.R.C.P.C, Szumacher, Ewa, M.D., M.Ed., F.R.C.P.C, Thomas, Gillian, B.Sc., M.D., F.R.C.P.C

“…Purpose To determine the short- and medium-term effects of a single high-dose-rate brachytherapy fraction of 15Gy and hypofractionated external beam radiation…”
Get full text

Two-fraction stereotactic ablative radiotherapy (SABR) versus two-fraction high dose rate (HDR) brachytherapy for localized prostate cancer: Does dose heterogeneity matter? by Correa, Rohann J.M., Morton, Gerard, Chung, Hans T., Tseng, Chia-Lin, Cheung, Patrick, Chu, William, Liu, Stanley K, McGuffin, Merrylee, Shahid, Anam, Davidson, Melanie, Ravi, Ananth, Helou, Joelle, Alayed, Yasir, Zhang, Liying, Mamedov, Alexandre, Loblaw, Andrew

“…•PSA kinetics and biochemical failure were similar with two-fractions of SABR or HDR.•Quality of life, acute and late toxicities were no different in the two…”
Get full text

Health-Related Quality of Life After Single-Fraction High-Dose-Rate Brachytherapy and Hypofractionated External Beam Radiotherapy for Prostate Cancer by Morton, Gerard C., M.B., F.R.C.P.C, Loblaw, D. Andrew, M.D., M.Sc., F.R.C.P.C, Chung, Hans, M.D., F.R.C.P.C, Tsang, Gail, M.D., F.R.A.N.Z.C.R, Sankreacha, Raxa, M.Sc, Deabreu, Andrea, Zhang, Liying, Ph.D, Mamedov, Alexandre, Cheung, Patrick, M.D., F.R.C.P.C, Batchelar, Deidre, Ph.D, Danjoux, Cyril, M.D., F.R.C.P.C, Szumacher, Ewa, M.D., M.Ed., F.R.C.P.C

“…Purpose To investigate the change in health-related quality of life for men after high-dose-rate brachytherapy and external beam radiotherapy for prostate…”
Get full text

Current topics in radiotherapy for genitourinary cancers: Consensus statements of the Genitourinary Radiation Oncologists of Canada by Morgan, Scott C, Morton, Gerard C, Berlin, Alejandro, Cheung, Patrick, Chung, Peter, Menard, Cynthia, Pickles, Tom, Souhami, Luis, Warde, Padraig R, Lukka, Himanshu R

“…Introduction: The biennial meeting of the Genitourinary Radiation Oncologists of Canada (GUROC) took place 22-23 November 2019. A consensus-building session…”
Get full text

Treatment options for localized prostate cancer by Keyes, Mira, Crook, Juanita, Morton, Gerard, Vigneault, Eric, Usmani, Nawaid, Morris, W James

“…To describe treatment options for clinically localized prostate cancer: radical prostatectomy, prostate brachytherapy, external beam radiation, and active…”
Get full text