Search Results - "Morton, Derrick"
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The RNA exosome and RNA exosome-linked disease
Published in RNA (Cambridge) (01-02-2018)“…The RNA exosome is an evolutionarily conserved, ribonuclease complex that is critical for both processing and degradation of a variety of RNAs. Cofactors that…”
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2
Snail promotes epithelial mesenchymal transition in breast cancer cells in part via activation of nuclear ERK2
Published in PloS one (14-08-2014)“…Snail transcription factor is up-regulated in several cancers and associated with increased tumor migration and invasion via induction of…”
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3
Inhibitor of differentiation 4 (ID4): From development to cancer
Published in Biochimica et biophysica acta (01-01-2015)“…Highly conserved Inhibitors of DNA-Binding (ID1–ID4) genes encode multi-functional proteins whose transcriptional activity is based on dominant negative…”
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A Drosophila model of Pontocerebellar Hypoplasia reveals a critical role for the RNA exosome in neurons
Published in PLoS genetics (09-07-2020)“…The RNA exosome is an evolutionarily-conserved ribonuclease complex critically important for precise processing and/or complete degradation of a variety of…”
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5
The importance of mentors and how to handle more than one mentor
Published in Pathogens and disease (22-06-2022)“…Abstract Working with multiple mentors is a critical way for students to expand their network, gain opportunities, and better prepare for future scholastic or…”
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The role of mentoring in promoting diversity equity and inclusion in STEM Education and Research
Published in Pathogens and disease (21-07-2022)“…Abstract The success of mentoring derives from active and respectful listening and the willingness to learn and accept opportunities for personal growth. This…”
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The Drosophila Nab2 RNA binding protein inhibits m6A methylation and male-specific splicing of Sex lethal transcript in female neuronal tissue
Published in eLife (17-07-2023)“…The Drosophila polyadenosine RNA binding protein Nab2, which is orthologous to a human protein lost in a form of inherited intellectual disability, controls…”
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Id4 dependent acetylation restores mutant-p53 transcriptional activity
Published in Molecular cancer (13-12-2013)“…The mechanisms that can restore biological activity of mutant p53 are an area of high interest given that mutant p53 expression is observed in one third of…”
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Combining Metabolomics and Experimental Evolution Reveals Key Mechanisms Underlying Longevity Differences in Laboratory Evolved Drosophila melanogaster Populations
Published in International journal of molecular sciences (19-01-2022)“…Experimental evolution with has been used extensively for decades to study aging and longevity. In recent years, the addition of DNA and RNA sequencing to this…”
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ID4 promotes AR expression and blocks tumorigenicity of PC3 prostate cancer cells
Published in Biochemical and biophysical research communications (09-09-2016)“…Deregulation of tumor suppressor genes is associated with tumorigenesis and the development of cancer. In prostate cancer, ID4 is epigenetically silenced and…”
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Using champion-oriented mindset to overcome the challenges of graduate school: impact of workshop for graduate school skills on underrepresented minority retention
Published in Pathogens and disease (13-08-2022)“…Abstract Despite efforts to increase diversity, a glaring underrepresentation of minorities (URM) persists in the fields of science, technology, engineering,…”
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An effective workshop on “How to be an Effective Mentor for Underrepresented STEM Trainees”
Published in Pathogens and disease (06-07-2022)“…Abstract Despite an increase in programming to promote persons excluded by their ethnicity or race (PEER) scholars, minorities remain underrepresented in many…”
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13
A Workshop to Enrich Physiological Understanding Through Hands-On Learning About Mitochondria-Endoplasmic Reticulum Contact Sites
Published in Advances in physiology education (01-12-2024)“…Physiology is an important field for students to gain a better understanding of biological mechanisms. Yet, many students often find it difficult to learn from…”
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A Workshop to Showcase the Diversity of Scientists to Middle School Students
Published in Advances in physiology education (01-06-2024)“…Identity matters in science, technology, engineering, mathematics, and medicine (STEMM), as it can affect long-term feelings of a sense of belonging, which may…”
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A workshop on mitochondria for students to improve understanding of science and hypothesis forming
Published in Advances in physiology education (01-12-2023)“…There remains a clear deficiency in recruiting middle school students in science, technology, engineering, mathematics, and medicine fields, especially for…”
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The RNA Exosome and Human Disease
Published in Methods in molecular biology (Clifton, N.J.) (2020)“…The evolutionarily conserved RNA exosome is a multisubunit ribonuclease complex that processes and/or degrades numerous RNAs. Recently, mutations in genes…”
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A pilot study on our non-traditional, varied writing accountability group for historically excluded and underrepresented persons in STEMM
Published in Heliyon (01-12-2023)“…Underrepresented faculty have higher burnout rates and lower grant attainment rates when compared with their non-minority counterparts. Many in science,…”
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TGF-β Effects on Prostate Cancer Cell Migration and Invasion Are Mediated by PGE2 through Activation of PI3K/AKT/mTOR Pathway
Published in Endocrinology (Philadelphia) (01-05-2013)“…TGF-β plays an important role in the progression of prostate cancer. It exhibits both tumor suppressor and tumor-promoting activities. Correlations between…”
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How to Select a Graduate School Program for a PhD in Biomedical Science
Published in Current protocols (01-06-2022)“…The goal of this article is to provide guidance for those who have decided to apply to graduate school with the plan to obtain a PhD in biomedical science…”
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Project Strengthen: An STEMM-focused career development workshop to prepare underrepresented minority students for graduate school
Published in iScience (20-10-2023)“…Maximizing Access to Research Careers (MARC) programs are aimed to increase diversity in science, technology, engineering, math, and medicine (STEMM) fields…”
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