Search Results - "Morton, David W"
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Essential Oil Quality and Purity Evaluation via FT-IR Spectroscopy and Pattern Recognition Techniques
Published in Applied sciences (01-10-2020)“…Essential oils are highly volatile, aromatic concentrated extracts from plants with wide applications. In this study, fast, easy-to-use attenuated total…”
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HPTLC and ATR/FTIR Characterization of Antioxidants in Different Rosemary Extracts
Published in Molecules (Basel, Switzerland) (07-10-2021)“…The effect of spontaneous fermentation by lactic acid bacteria on the extraction yield of bioactive compounds and antioxidant activity from rosemary leaf…”
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High-Performance Thin-Layer Chromatography Hyphenated with Microchemical and Biochemical Derivatizations in Bioactivity Profiling of Marine Species
Published in Marine drugs (03-03-2019)“…Marine organisms produce an array of biologically active natural products, many of which have unique structures that have not been found in terrestrial…”
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Essential oils and functional herbs for healthy aging
Published in Neural regeneration research (01-03-2019)“…As total life expectancy increases, the prevalence of age-related diseases such as diabetes and Alzheimer's disease is also increasing. Many hypotheses about…”
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Bioassay-Guided Assessment of Antioxidative, Anti-Inflammatory and Antimicrobial Activities of Extracts from Medicinal Plants via High-Performance Thin-Layer Chromatography
Published in Molecules (Basel, Switzerland) (01-10-2023)“…Natural products and their analogues have contributed significantly to treatment options, especially for anti-inflammatory and infectious diseases. Thus, the…”
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Probing into the Molecular Requirements for Antioxidant Activity in Plant Phenolic Compounds Utilizing a Combined Strategy of PCA and ANN
Published in Combinatorial chemistry & high throughput screening (01-01-2017)“…This study investigates molecular structural requirements that are responsible for the antioxidant activity in phenolic compounds. Antioxidant activity of…”
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The Power of HPTLC-ATR-FTIR Hyphenation in Bioactivity Analysis of Plant Extracts
Published in Applied sciences (15-11-2020)“…Given the simplicity in sample preparation and application, thin-layer chromatography (TLC) and high-performance thin-layer chromatography (HPTLC) as its most…”
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Hyphenated TLC as a Tool in the Effect-Directed Discovery of Bioactive Natural Products
Published in Applied sciences (01-02-2020)“…Complex samples such as botanical extracts contain hundreds of compounds. Since we can only identify compounds that are stable, extractable, separable and…”
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Development and Validation of an LC-MS/MS Method for Simultaneous Determination of Short Peptide-Based Drugs in Human Blood Plasma
Published in Molecules (Basel, Switzerland) (01-11-2022)“…A novel HPLC-ESI-MS/MS method for simultaneous gonadotropin-releasing hormone (GnRH) analogs and somatostatin analog quantitation was developed and validated…”
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Isolation of Bioactive Pentacyclic Triterpenoid Acids from Olive Tree Leaves with Flash Chromatography
Published in Applied sciences (01-02-2022)“…The present study reports on the use of the flash chromatography for the isolation and purification of oleanolic and maslinic acids from olive leaf extracts…”
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HPTLC - Bioautographic methods for selective detection of the antioxidant and α-amylase inhibitory activity in plant extracts
Published in MethodsX (01-01-2018)“…A high-performance thin-layer chromatography (HPTLC) method was developed for quantification of α-amylase inhibitory activity and stigmasterol content in ant…”
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A molecular approach in drug development for Alzheimer’s disease
Published in Biomedicine & pharmacotherapy (01-10-2018)“…[Display omitted] •Current single target FDA approved drugs only provide symptomatic treatments.•Dual binding AChE inhibitors can positively modify the course…”
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13
In silico modelling of pesticide aquatic toxicity
Published in Combinatorial chemistry & high throughput screening (01-01-2014)“…Human activities have introduced tens of thousands of chemicals into water systems around the world which has significantly impacted water quality and aquatic…”
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High-performance thin-layer chromatography HPTLC-direct bioautography as a method of choice for alpha-amylase and antioxidant activity evaluation in marine algae
Published in Journal of chromatography. A (29-12-2017)“…High-Performance Thin-layer chromatography (HPTLC) combined with DPPH free radical method and α-amylase bioassay was used to compare antioxidant and…”
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15
QSAR: an in silico approach for predicting the partitioning of pesticides into breast milk
Published in Combinatorial chemistry & high throughput screening (01-03-2013)“…The aim of this study was to develop an in silico Quantitative Structure Activity Relationship (QSAR) model capable of predicting partitioning of pesticides…”
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Bioassay-guided identification of α-amylase inhibitors in herbal extracts
Published in Journal of Chromatography A (07-06-2020)“…•Culinary herbs exhibit antioxidant activity, α-amylase inhibition and provide neuroprotection.•Pentacyclic triterpenes are α-amylase inhibitors with…”
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The assessment and characterisation of drug plasma protein binding in the body using QSAR
Published in Mini reviews in medicinal chemistry (01-01-2014)“…Most drugs are carried from the site of absorption to their intended site of action (target site) by the bloodstream, either dissolved in the serum or bound to…”
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A mechanistic approach of chromium (VI) adsorption onto manganese oxides and boehmite
Published in Journal of environmental chemical engineering (01-04-2020)“…[Display omitted] •Cr(VI) adsorption has been studied using manganese oxides and boehmite.•Langmuir equation could correlate Cr(VI) adsorption data…”
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High-performance thin-layer chromatography linked with (bio)assays and FTIR-ATR spectroscopy as a method for discovery and quantification of bioactive components in native Australian plants
Published in Journal of pharmaceutical and biomedical analysis (30-05-2020)“…•Australian native plants exhibit enzyme inhibitory and antioxidant activities.•ATR-FTIR-spectroscopy is used for chemical characterisation of plant…”
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A new integrated HPTLC - ATR/FTIR approach in marine algae bioprofiling
Published in Journal of pharmaceutical and biomedical analysis (10-09-2020)“…•HPTLC with FTIR-ATR spectroscopy helped identify algae bioactive components.•Extract composition was significantly affected by the extraction solvent…”
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