Search Results - "Mortimer, Amanda D"
-
1
Dopamine quinone modifies and decreases the abundance of the mitochondrial selenoprotein glutathione peroxidase 4
Published in Free radical biology & medicine (01-12-2013)“…Oxidative stress and mitochondrial dysfunction are known to contribute to the pathogenesis of Parkinson's disease. Dopaminergic neurons may be more sensitive…”
Get full text
Journal Article -
2
comparison of the high-affinity peripheral benzodiazepine receptor ligands DAA1106 and (R)-PK11195 in rat models of neuroinflammation: implications for PET imaging of microglial activation
Published in Journal of neurochemistry (01-09-2007)“…Activated microglia are an important feature of many neurological diseases and can be imaged in vivo using…”
Get full text
Journal Article -
3
Acquired dysregulation of dopamine homeostasis reproduces features of Parkinson’s disease
Published in NPJ Parkinson's Disease (13-11-2020)“…The catecholamine neurotransmitter dopamine has the potential to act as an endogenous neurotoxin when its vesicular sequestration is dysregulated. Despite…”
Get full text
Journal Article -
4
The high‐affinity peripheral benzodiazepine receptor ligand [11C]DAA1106 can be used to image microglia in animal models of Parkinson's disease and neuroinflammation in vivo using PET
Published in The FASEB journal (01-04-2007)“…Activated microglia are an important feature of several neurological diseases. We propose that activated microglia can be imaged using Positron Emission…”
Get full text
Journal Article -
5