Search Results - "Mortezaee, Keywan"

B7-H3 immunoregulatory roles in cancer by Mortezaee, Keywan

“…B7 homolog 3 (B7-H3, also called CD276) is a checkpoint of B7 family that is aberrantly and consistently expressed in several human cancers, and its…”
Get full text

HHLA2 immune-regulatory roles in cancer by Mortezaee, Keywan

“…Human endogenous retrovirus H long terminal repeat-associating protein 2 (HHLA2 or B7-H7) is a newly discovered B7 family member. HHLA2 is aberrantly expressed…”
Get full text

Steps in metastasis: an updated review by Majidpoor, Jamal, Mortezaee, Keywan

“…Metastasis is the most complex and deadly event. Tumor-stromal interface is a place where invasion of tumor cells in the form of single-cell or collective…”
Get full text

Extracellular matrix (ECM) stiffness and degradation as cancer drivers by Najafi, Masoud, Farhood, Bagher, Mortezaee, Keywan

“…Alteration in the density and composition of extracellular matrix (ECM) occurs in tumors. The alterations toward both stiffness and degradation are contributed…”
Get full text

Cancer stem cells (CSCs) in cancer progression and therapy by Najafi, Masoud, Farhood, Bagher, Mortezaee, Keywan

“…Cancer stem cells (CSCs) are self‐renewable cell types that are identified in most types of liquid and solid cancers and contributed to tumor onset, expansion,…”
Get full text

Angiogenesis as a hallmark of solid tumors - clinical perspectives by Majidpoor, Jamal, Mortezaee, Keywan

“…Background Angiogenesis is a key and early step in tumorigenesis, and is known as a hallmark of solid tumors and a key promoter of tumor recurrence. Unlike…”
Get full text

Inflammasome: Its role in traumatic brain and spinal cord injury by Mortezaee, Keywan, Khanlarkhani, Neda, Beyer, Cordian, Zendedel, Adib

“…Traumatic brain injury (TBI) and spinal cord injury (SCI) are pathological events that lead to neuropathological conditions which have in consequence the…”
Get full text

Melatonin application in targeting oxidative‐induced liver injuries: A review by Mortezaee, Keywan, Khanlarkhani, Neda

“…It is believed that oxidative stress is a key causing factor of liver damage induced by a variety of agents, and it is a major contributing factor in almost…”
Get full text

Cyclooxygenase‐2 in cancer: A review by Hashemi Goradel, Nasser, Najafi, Masoud, Salehi, Eniseh, Farhood, Bagher, Mortezaee, Keywan

“…Cyclooxygenase‐2 (COX‐2) is frequently expressed in many types of cancers exerting a pleiotropic and multifaceted role in genesis or promotion of…”
Get full text

Advances in dendritic cell vaccination therapy of cancer by Najafi, Sajad, Mortezaee, Keywan

“…Traditionally, vaccines have helped eradication of several infectious diseases and also saved millions of lives in the human history. Those prophylactic…”
Get full text

Interleukin-6 in SARS-CoV-2 induced disease: Interactions and therapeutic applications by Majidpoor, Jamal, Mortezaee, Keywan

“…Interleukin-6 (IL-6) is a multi-tasking cytokine that represents high activity in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…”
Get full text

Key promoters of tumor hallmarks by Mortezaee, Keywan, Majidpoor, Jamal

“…Evolution of tumor hallmarks is a result of accommodation of tumor cells with their nearby milieu called tumor microenvironment (TME). Accommodation or…”
Get full text

The current knowledge concerning solid cancer and therapy by Najafi, Masoud, Majidpoor, Jamal, Toolee, Heidar, Mortezaee, Keywan

“…Solid cancers comprise a large number of new cases and deaths from cancer each year globally. There are a number of strategies for addressing tumors raised…”
Get full text

Roles for macrophage-polarizing interleukins in cancer immunity and immunotherapy by Mortezaee, Keywan, Majidpoor, Jamal

“…Macrophages are the most abundant and one of the most critical cells of tumor immunity. They provide a bridge between innate and adaptive immunity through…”
Get full text

Cancer stem cells in immunoregulation and bypassing anti-checkpoint therapy by Rouzbahani, Elnaz, Majidpoor, Jamal, Najafi, Sajad, Mortezaee, Keywan

“…Tumor microenvironment (TME) takes critical roles in tumor resistance to immune checkpoint inhibitors (ICIs) including anti-programmed death-1 (PD-1) or…”
Get full text

(Im)maturity in Tumor Ecosystem by Mortezaee, Keywan, Majidpoor, Jamal

“…Tumors have special features that make them distinct from their normal counterparts. Immature cells in a tumor mass and their critical contributions to the…”
Get full text

Curcumin as an anti‐inflammatory agent: Implications to radiotherapy and chemotherapy by Farhood, Bagher, Mortezaee, Keywan, Goradel, Nasser Hashemi, Khanlarkhani, Neda, Salehi, Ensieh, Nashtaei, Maryam Shabani, Najafi, Masoud, Sahebkar, Amirhossein

“…Cancer is the second cause of death worldwide. Chemotherapy and radiotherapy are the most common modalities for the treatment of cancer. Experimental studies…”
Get full text

Extracellular‐signal‐regulated kinase/mitogen‐activated protein kinase signaling as a target for cancer therapy: an updated review by Najafi, Masoud, Ahmadi, Amirhossein, Mortezaee, Keywan

“…Mitogen‐activated protein kinase (MAPK) signaling pathway is activated in a wide spectrum of human tumors, exhibiting cardinal oncogenic roles and sustained…”
Get full text

CD8 + T Cells in SARS-CoV-2 Induced Disease and Cancer-Clinical Perspectives by Mortezaee, Keywan, Majidpoor, Jamal

“…Dysregulated innate and adaptive immunity is a sign of SARS-CoV-2-induced disease and cancer. CD8 T cells are important cells of the immune system. The cells…”
Get full text

Redox interactions and genotoxicity of metal-based nanoparticles: A comprehensive review by Mortezaee, Keywan, Najafi, Masoud, Samadian, Hadi, Barabadi, Hamed, Azarnezhad, Asaad, Ahmadi, Amirhossein

“…Nanotechnology is a growing science that may provide several new applications for medicine, food preservation, diagnostic technologies, and sanitation. Despite…”
Get full text