Search Results - "Mortensen, Preben B."
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Stress in Puberty Unmasks Latent Neuropathological Consequences of Prenatal Immune Activation in Mice
Published in Science (American Association for the Advancement of Science) (01-03-2013)“…Prenatal infection and exposure to traumatizing experiences during peripuberty have each been associated with increased risk for neuropsychiatric disorders…”
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Autoimmune Diseases and Severe Infections as Risk Factors for Schizophrenia: A 30-Year Population-Based Register Study
Published in The American journal of psychiatry (01-12-2011)“…Objective:Autoimmune diseases have been associated with an increased risk of schizophrenia. It has been suggested that brain-reactive autoantibodies are part…”
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3
Autoimmune diseases and infections as risk factors for schizophrenia
Published in Annals of the New York Academy of Sciences (01-07-2012)“…Immunological hypotheses have become increasingly prominent when studying the etiology of schizophrenia. Autoimmune diseases, and especially the number of…”
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4
Parental Infections Before, During, and After Pregnancy as Risk Factors for Mental Disorders in Childhood and Adolescence: A Nationwide Danish Study
Published in Biological psychiatry (1969) (15-02-2019)“…Previous studies have shown associations between maternal infections during pregnancy and increased risks of schizophrenia and autism spectrum disorder in the…”
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5
Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses
Published in Nature medicine (01-07-2023)“…Depression is a common psychiatric disorder and a leading cause of disability worldwide. Here we conducted a genome-wide association study meta-analysis of six…”
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6
Obsessive-Compulsive Disorder and Autism Spectrum Disorders: Longitudinal and Offspring Risk
Published in PloS one (11-11-2015)“…Despite substantial similarities and overlaps in the pathophysiology of obsessive-compulsive disorders (OCD) and autism spectrum disorders, little is known…”
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Individual and combined effects of maternal anemia and prenatal infection on risk for schizophrenia in offspring
Published in Schizophrenia research (01-04-2016)“…Abstract Background Maternal iron deficiency and infection during pregnancy have individually been associated with increased risk of schizophrenia in the…”
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8
Temporal changes in sex‐ and age‐specific incidence profiles of mental disorders—A nationwide study from 1970 to 2016
Published in Acta psychiatrica Scandinavica (01-06-2022)“…Objective Information on mental disorders over time is critical for documenting changes in population burden, and aiding understanding of potential causal and…”
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ADuLT: An efficient and robust time-to-event GWAS
Published in Nature communications (09-09-2023)“…Proportional hazards models have been proposed to analyse time-to-event phenotypes in genome-wide association studies (GWAS). However, little is known about…”
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From population to neuron: exploring common mediators for metabolic problems and mental illnesses
Published in Molecular psychiatry (01-08-2021)“…Major mental illnesses such as schizophrenia (SZ) and bipolar disorder (BP) frequently accompany metabolic conditions, but their relationship is still unclear,…”
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Interactive effects between hemizygous 15q13.3 microdeletion and peripubertal stress on adult behavioral functions
Published in Neuropsychopharmacology (New York, N.Y.) (01-03-2019)“…15q13.3 microdeletion is one of several gene copy number variants (CNVs) conferring increased risk of psychiatric and neurological disorders. This…”
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Adolescent residential mobility, genetic liability and risk of schizophrenia, bipolar disorder and major depression
Published in British journal of psychiatry (01-07-2020)“…Residential mobility during upbringing, and especially adolescence, is associated with multiple negative mental health outcomes. However, whether associations…”
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13
Secondary depression in severe anxiety disorders: a population-based cohort study in Denmark
Published in The Lancet. Psychiatry (01-06-2015)“…Summary Background Depression and anxiety disorders are highly comorbid conditions and a worldwide disease burden; however, large-scale studies delineating…”
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14
Parental income as a marker for socioeconomic position during childhood and later risk of developing a secondary care-diagnosed mental disorder examined across the full diagnostic spectrum: a national cohort study
Published in BMC medicine (16-11-2020)“…Links between parental socioeconomic position during childhood and subsequent risks of developing mental disorders have rarely been examined across the…”
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Vagotomy and the risk of mental disorders: A nationwide population‐based study
Published in Acta psychiatrica Scandinavica (01-01-2022)“…Objective To investigate vagotomy, the severance of the vagus nerve, and its association with mental disorders, as gut‐brain communication partly mediated by…”
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Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns for link to disease
Published in PloS one (10-12-2018)“…Mitochondria play a significant role in human diseases. However, disease associations with mitochondrial DNA (mtDNA) SNPs have proven difficult to replicate…”
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Influence of Polygenic Risk Scores on the Association Between Infections and Schizophrenia
Published in Biological psychiatry (1969) (15-10-2016)“…Abstract Background Several studies have suggested an important role of infections in the etiology of schizophrenia; however, shared genetic liability toward…”
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Predicting ADHD by Assessment of Rutter's Indicators of Adversity in Infancy
Published in PloS one (29-06-2016)“…Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder with early onset. ADHD is associated with significant morbidity and…”
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Maternal pregnancy-related infections and autism spectrum disorder—the genetic perspective
Published in Translational psychiatry (16-08-2022)“…Autism spectrum disorder (ASD) refers to a group of neurodevelopmental disorders which include deficits in behavior, social interaction and communication. ASD…”
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Exposure to air pollution during childhood and risk of developing schizophrenia: a national cohort study
Published in The Lancet. Planetary health (01-02-2020)“…Ambient air pollution affects neurological function, but its association with schizophrenia risk is unclear. We investigated exposure to nitrogen oxides (NOX)…”
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