Search Results - "Mortensen, Lise Saksø"

Accessing radiation response using hypoxia PET imaging and oxygen sensitive electrodes: A preclinical study by Mortensen, Lise Saksø, Busk, Morten, Nordsmark, Marianne, Jakobsen, Steen, Theil, Jørn, Overgaard, Jens, Horsman, Michael R

“…Abstract Purpose Tumor hypoxia is a known cause of resistance to radiotherapy. The aim of this study was to investigate the prognostic value of hypoxia…”
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Plasma proteins as prognostic biomarkers in radiotherapy treated head and neck cancer patients by Brøndum, Line, Eriksen, Jesper Grau, Singers Sørensen, Brita, Mortensen, Lise Saksø, Toustrup, Kasper, Overgaard, Jens, Alsner, Jan

“…Blood-based protein biomarkers can be a useful tool as pre-treatment prognostic markers, as they can reflect both variations in the tumor microenvironment and…”
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FAZA PET/CT hypoxia imaging in patients with squamous cell carcinoma of the head and neck treated with radiotherapy: Results from the DAHANCA 24 trial by Mortensen, Lise Saksø, Johansen, Jørgen, Kallehauge, Jesper, Primdahl, Hanne, Busk, Morten, Lassen, Pernille, Alsner, Jan, Sørensen, Brita S, Toustrup, Kasper, Jakobsen, Steen, Petersen, Jørgen, Petersen, Henrik, Theil, Jørn, Nordsmark, Marianne, Overgaard, Jens

“…Abstract Purpose Hypoxia is a cause of resistance to radiotherapy, especially in patients with head and neck squamous cell carcinoma (HNSCC). The purpose of…”
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Influence of FAZA PET hypoxia and HPV-status for the outcome of head and neck squamous cell carcinoma (HNSCC) treated with radiotherapy: Long-term results from the DAHANCA 24 trial (NCT01017224) by Saksø, Mette, Mortensen, Lise Saksø, Primdahl, Hanne, Johansen, Jørgen, Kallehauge, Jesper, Hansen, Christian Rønn, Overgaard, Jens

“…•18F-FAZA imaging was used in a prospective trial of 38 HNSCC patients completing radiotherapy.•Within 5 years of follow-up, nine locoregional treatment…”
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LET-painting increases tumour control probability in hypoxic tumours by Bassler, Niels, Toftegaard, Jakob, Lühr, Armin, Sørensen, Brita Singers, Scifoni, Emanuele, Krämer, Michael, Jäkel, Oliver, Mortensen, Lise Saksø, Overgaard, Jens, Petersen, Jørgen B

“…LET-painting was suggested as a method to overcome tumour hypoxia. In vitro experiments have demonstrated a well-established relationship between the oxygen…”
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Imaging hypoxia to improve radiotherapy outcome by Horsman, Michael R., Mortensen, Lise Saksø, Petersen, Jørgen B., Busk, Morten, Overgaard, Jens

“…Hypoxia can affect clinical outcome after radiotherapy, resulting in reduced local tumour control and increased malignant progression. Hence, its detection is…”
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Validation of a 15-gene hypoxia classifier in head and neck cancer for prospective use in clinical trials by Toustrup, Kasper, Sørensen, Brita Singers, Metwally, Mohamed A Hassan, Tramm, Trine, Mortensen, Lise Saksø, Overgaard, Jens, Alsner, Jan

“…In head and neck squamous cell carcinomas (HNSCC) hypoxic radioresistance can be reduced by use of the hypoxic modifier nimorazole, as shown in the DAHANCA 5…”
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An evaluation of multiplex bead-based analysis of cytokines and soluble proteins in archived lithium heparin plasma, EDTA plasma and serum samples by Brøndum, Line, Sørensen, Brita Singers, Eriksen, Jesper Grau, Mortensen, Lise Saksø, Lønbro, Simon, Overgaard, Jens, Alsner, Jan

“…Objective: To assess the usability of archived plasma and serum by multiplex (Luminex) analysis of circulating proteins (analytes) by evaluating the day to day…”
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Individual patient data meta-analysis of FMISO and FAZA hypoxia PET scans from head and neck cancer patients undergoing definitive radio-chemotherapy by Zschaeck, Sebastian, Löck, Steffen, Hofheinz, Frank, Zips, Daniel, Saksø Mortensen, Lise, Zöphel, Klaus, Troost, Esther G.C., Boeke, Simon, Saksø, Mette, Mönnich, David, Seidlitz, Annekatrin, Johansen, Jørgen, Skripcak, Tomas, Gregoire, Vincent, Overgaard, Jens, Baumann, Michael, Krause, Mechthild

“…•The two most commonly used hypoxia PET tracers FMISO and FAZA can be analyzed jointly.•Hypoxia PET derived parameters delivered strong and independent…”
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446: Role of prophylactic cranial irradiation for patients with limited disease small cell lung cancer by Linde, Sara, Schmidt, Hjørdis Hjalting, Hoffmann, Lone, Tvilum, Marie, Lutz, Christina Maria, Mortensen, Lise Saksø, Khalil, Azza Ahmed, Knap, Marianne Marquard, Møller, Ditte Sloth

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Identifying hypoxia in human tumors: A correlation study between 18F-FMISO PET and the Eppendorf oxygen-sensitive electrode by Mortensen, Lise Saksø, Buus, Simon, Nordsmark, Marianne, Bentzen, Lise, Munk, Ole Lajord, Keiding, Susanne, Overgaard, Jens

“…Polarographic oxygen-sensitive electrodes have demonstrated prognostic significance of hypoxia. However, its routine application is limited. (18)F-FMISO PET…”
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