Search Results - "Mortara, A."

The diverse and dynamic nature of Leishmania parasitophorous vacuoles studied by multidimensional imaging by Real, Fernando, Mortara, Renato A

“…An important area in the cell biology of intracellular parasitism is the customization of parasitophorous vacuoles (PVs) by prokaryotic or eukaryotic…”
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Trypanosoma cruzi subverts the sphingomyelinase-mediated plasma membrane repair pathway for cell invasion by Fernandes, Maria Cecilia, Cortez, Mauro, Flannery, Andrew R, Tam, Christina, Mortara, Renato A, Andrews, Norma W

“…Upon host cell contact, the protozoan parasite Trypanosoma cruzi triggers cytosolic Ca(2+) transients that induce exocytosis of lysosomes, a process required…”
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Rac1/WAVE2 and Cdc42/N-WASP Participation in Actin-Dependent Host Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi by Bonfim-Melo, Alexis, Ferreira, Éden R, Mortara, Renato A

“…This study evaluated the participation of host cell Rho-family GTPases and their effector proteins in the actin-dependent invasion by extracellular amastigotes…”
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Impact of diabetes on COVID-19-related in-hospital mortality: a retrospective study from Northern Italy by Ciardullo, S., Zerbini, F., Perra, S., Muraca, E., Cannistraci, R., Lauriola, M., Grosso, P., Lattuada, G., Ippoliti, G., Mortara, A., Manzoni, G., Perseghin, G.

“…Purpose The purpose of this study was to evaluate the impact of pre-existing diabetes on in-hospital mortality in patients admitted for Coronavirus Disease…”
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DNA damage and oxidative stress in human cells infected by Trypanosoma cruzi by Florentino, Pilar T V, Mendes, Davi, Vitorino, Francisca Nathalia L, Martins, Davi J, Cunha, Julia P C, Mortara, Renato A, Menck, Carlos F M

“…Trypanosoma cruzi is the etiologic agent of Chagas' disease. Infected cells with T. cruzi activate several responses that promote unbalance of reactive oxygen…”
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Amastigote Synapse: The Tricks of Trypanosoma cruzi Extracellular Amastigotes by Bonfim-Melo, Alexis, Ferreira, Eden R, Florentino, Pilar T V, Mortara, Renato A

“…To complete its life cycle within the mammalian host, , the agent of Chagas' disease, must enter cells. Trypomastigotes originating from the insect vector…”
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ERM Proteins Play Distinct Roles in Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi by Ferreira, Éden R, Bonfim-Melo, Alexis, Cordero, Esteban M, Mortara, Renato A

“…The protozoan parasite is the causative agent of Chagas' disease. In mammalian hosts, alternates between trypomastigote and amastigote forms. Additionally,…”
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Parasite-Mediated Remodeling of the Host Microfilament Cytoskeleton Enables Rapid Egress of Trypanosoma cruzi following Membrane Rupture by Ferreira, Eden R, Bonfim-Melo, Alexis, Burleigh, Barbara A, Costales, Jaime A, Tyler, Kevin M, Mortara, Renato A

“…Chagas' disease arises as a direct consequence of the lytic cycle of Trypanosoma cruzi in the mammalian host. While invasion is well studied for this pathogen,…”
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Cytokines and microbicidal molecules regulated by IL-32 in THP-1-derived human macrophages infected with New World Leishmania species by Dos Santos, Jéssica Cristina, Heinhuis, Bas, Gomes, Rodrigo Saar, Damen, Michelle S M A, Real, Fernando, Mortara, Renato A, Keating, Samuel T, Dinarello, Charles A, Joosten, Leo A B, Ribeiro-Dias, Fátima

“…Interleukin-32 (IL-32) is expressed in lesions of patients with American Tegumentary Leishmaniasis (ATL), but its precise role in the disease remains unknown…”
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BALB/c and C57BL/6 Mice Cytokine Responses to Trypanosoma cruzi Infection Are Independent of Parasite Strain Infectivity by Ferreira, Bianca L, Ferreira, Éden R, de Brito, Marlon V, Salu, Bruno R, Oliva, Maria L V, Mortara, Renato A, Orikaza, Cristina M

“…is the etiologic agent of Chagas' disease, which affects 6-7 million people worldwide. Different strains of present specific genotypic and phenotypic…”
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Candida albicans : The Ability to Invade Epithelial Cells and Survive under Oxidative Stress Is Unlinked to Hyphal Length by Maza, Paloma K, Bonfim-Melo, Alexis, Padovan, Ana C B, Mortara, Renato A, Orikaza, Cristina M, Ramos, Lilian M Damas, Moura, Tauany R, Soriani, Frederico M, Almeida, Ricardo S, Suzuki, Erika, Bahia, Diana

“…In its hyphal form, invades epithelial and endothelial cells by two distinct mechanisms: active penetration and induced endocytosis. The latter is dependent on…”
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Trypanosoma cruzi: role of δ-amastin on extracellular amastigote cell invasion and differentiation by Cruz, Mário C, Souza-Melo, Normanda, da Silva, Claudio Vieira, Darocha, Wanderson Duarte, Bahia, Diana, Araújo, Patrícia R, Teixeira, Santuza R, Mortara, Renato A

“…Trypanosoma cruzi is a protozoan parasite that comprises different phylogenetic groups and is the causative agent of Chagas' disease. Different T. cruzi…”
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CD4+CD25+ T Cells in Skin Lesions of Patients with Cutaneous Leishmaniasis Exhibit Phenotypic and Functional Characteristics of Natural Regulatory T Cells by Campanelli, Ana P., Roselino, Ana M., Cavassani, Karen A., Pereira, Marcelo S. F., Mortara, Renato A., Brodskyn, Claudia I., Gonçalves, Heitor S., Belkaid, Yasmine, Barral-Netto, Manoel, Barral, Aldina, Silva, João S.

“…Endogenous regulatory T (Treg) cells are involved in the control of infections, including Leishmania infection in mice. Leishmania viannia braziliensis is the…”
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Fusion between Leishmania amazonensis and Leishmania major parasitophorous vacuoles: live imaging of coinfected macrophages by Real, Fernando, Mortara, Renato A, Rabinovitch, Michel

“…Protozoan parasites of the genus Leishmania alternate between flagellated, elongated extracellular promastigotes found in insect vectors, and round-shaped…”
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Epidemiology, pathophysiology and contemporary management of cardiogenic shock - a position statement from the Heart Failure Association of the European Society of Cardiology (vol 22, pg 1315, 2020) by Chioncel, O, Parissis, J, Mebazaa, A, Thiele, H, Desch, S, Bauersachs, J, Harjola, VP, Antohi, EL, Arrigo, M, Gal, TB, Celutkiene, J, Collins, SP, DeBacker, D, Iliescu, VA, Jankowska, E, Jaarsma, T, Keramida, K, Lainscak, M, Lund, LH, Lyon, AR, Masip, J, Metra, M, Miro, O, Mortara, A, Mueller, C, Mullens, W, Nikolaou, M, Piepoli, M, Price, S, Rosano, G, Vieillard-Baron, A, Weinstein, JM, Anker, SD, Filippatos, G, Ruschitzka, F, Coats, AJS, Seferovic, P

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A Carbohydrate Moiety of Secreted Stage-Specific Glycoprotein 4 Participates in Host Cell Invasion by Trypanosoma cruzi Extracellular Amastigotes by Florentino, Pilar T V, Real, Fernando, Orikaza, Cristina M, da Cunha, Julia P C, Vitorino, Francisca N L, Cordero, Esteban M, Sobreira, Tiago J P, Mortara, Renato A

“…is the etiologic agent of Chagas' disease. It is known that amastigotes derived from trypomastigotes in the extracellular milieu are infective and …”
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Peptide R18H from BRN2 Transcription Factor POU Domain Displays Antitumor Activity In Vitro and In Vivo and Induces Apoptosis in B16F10-Nex2 Cells by da Cunha, Fernanda F M, Mugnol, Katia C U, de Melo, Filipe M, Nascimento, Marta V S Q, de Azevedo, Ricardo A, Santos, Raquel T S, Magalhães, Jéssica A, Miguel, Danilo C, Tada, Dayane B, Mortara, Renato A, Travassos, Luiz R, Arruda, Denise C

“…BRN2 transcription factor is associated with the development of malignant melanoma. The cytotoxic activities and cell death mechanism against B16F10-Nex2 cells…”
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Leishmania (Viannia) braziliensis Inositol Phosphorylceramide: Distinctive Sphingoid Base Composition by De Castro Levatti, Erica V, Toledo, Marcos S, Watanabe Costa, Renata, Bahia, Diana, Mortara, Renato A, Takahashi, Helio K, Straus, Anita H

“…Inositol phosphorylceramide (IPC), the major sphingolipid in the genus but not found in mammals, is considered a potentially useful target for chemotherapy…”
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Effective Topical Treatment of Subcutaneous Murine B16F10-Nex2 Melanoma By the Antimicrobial Peptide Gomesin by Rodrigues, Elaine G., Dobroff, Andrey S.S., Cavarsan, Clarissa F., Paschoalin, Thaysa, Nimrichter, Leonardo, Mortara, Renato A., Santos, Edson Lucas, Fázio, Marcos A., Miranda, Antonio, Daffre, Sirlei, Travassos, Luiz R.

“…Gomesin is a potent antimicrobial peptide (AMP) isolated from hemocytes of the spider Acanthoscurria gomesiana. The present study aimed at determining whether…”
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The repetitive cytoskeletal protein H49 of Trypanosoma cruzi is a calpain-like protein located at the flagellum attachment zone by Galetović, Alexandra, Souza, Renata T, Santos, Marcia R M, Cordero, Esteban M, Bastos, Izabela M D, Santana, Jaime M, Ruiz, Jeronimo C, Lima, Fabio M, Marini, Marjorie M, Mortara, Renato A, da Silveira, José Franco

“…Trypanosoma cruzi has a single flagellum attached to the cell body by a network of specialized cytoskeletal and membranous connections called the flagellum…”
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