Search Results - "Mortadza, Sharifah Alawieyah Syed"
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Ethanol Induces Microglial Cell Death via the NOX/ROS/PARP/TRPM2 Signalling Pathway
Published in Antioxidants (09-12-2020)“…Microglial cells are the primary immune cell resident in the brain. Growing evidence indicates that microglial cells play a prominent role in alcohol-induced…”
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Melastatin-related transient receptor potential 2 channel in Aβ42-induced neuroinflammation: implications to Alzheimer's disease mechanism and development of therapeutics
Published in Neural regeneration research (01-03-2018)“…In response to damage and infection or in contact with damage/pathogen-associated molecular patterns (DAMP/PAMP) molecules, microglial cells become activated…”
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Kefir and Its Biological Activities
Published in Foods (27-05-2021)“…Kefir is a fermented beverage with renowned probiotics that coexist in symbiotic association with other microorganisms in kefir grains. This beverage…”
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TRPM2 Channel-Mediated ROS-Sensitive Ca(2+) Signaling Mechanisms in Immune Cells
Published in Frontiers in immunology (2015)“…Transient receptor potential melastatin 2 (TRPM2) proteins form Ca(2+)-permeable cationic channels that are potently activated by reactive oxygen species…”
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TRPM2 Channel-Mediated ROS-Sensitive Ca2+ Signaling Mechanisms in Immune Cells
Published in Frontiers in immunology (07-08-2015)“…Transient receptor potential melastatin 2 (TRPM2) proteins form Ca 2+ -permeable cationic channels that are potently activated by reactive oxygen species…”
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Carcinoma-specific expression of P2Y11 receptor and its contribution in ATP-induced purinergic signalling and cell migration in human hepatocellular carcinoma cells
Published in Oncotarget (06-06-2017)“…Extracellular ATP-induced Ca2+ signalling is critical in regulating diverse physiological and disease processes. Emerging evidence suggests high concentrations…”
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Clinical and Preclinical Studies of Fermented Foods and Their Effects on Alzheimer's Disease
Published in Antioxidants (29-04-2022)“…The focus on managing Alzheimer's disease (AD) is shifting towards prevention through lifestyle modification instead of treatments since the currently…”
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A critical role of TRPM2 channel in Aβ42‐induced microglial activation and generation of tumor necrosis factor‐α
Published in Glia (01-03-2018)“…Amyloid β (Aβ)‐induced neuroinflammation plays an important part in Alzheimer's disease (AD). Emerging evidence supports a role for the transient receptor…”
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A critical role of TRPM2 channel in A[beta]42-induced microglial activation and generation of tumor necrosis factor-[alpha]
Published in Glia (01-03-2018)“…Amyloid [beta] (A[beta])-induced neuroinflammation plays an important part in Alzheimer's disease (AD). Emerging evidence supports a role for the transient…”
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A critical role of TRPM2 channel in Aβ 42 -induced microglial activation and generation of tumor necrosis factor-α
Published in Glia (01-03-2018)“…Amyloid β (Aβ)-induced neuroinflammation plays an important part in Alzheimer's disease (AD). Emerging evidence supports a role for the transient receptor…”
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Microglial trpm2 channel activation and its relationship to neurodegenerative diseases
Published 01-01-2017Get full text
Dissertation