Search Results - "Mortada, Nahed D"

Assessment of antifungal efficacy of itraconazole loaded aspasomal cream: comparative clinical study by Lamie, Caroline, Elmowafy, Enas, Ragaie, Maha H., Attia, Dalia A., Mortada, Nahed D.

“…Topical conveyance of antifungal agents like itraconazole ITZ has been giving good grounds for expecting felicitous antifungal medicines. The defiance of…”
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Back to Nature: Development and Optimization of Bioinspired Nanocarriers for Potential Breast Cancer Treatment by Safwat, Sally, Hathout, Rania M., Ishak, Rania A. H., Mortada, Nahed D.

“…This study focuses on the preparation and optimization of caffeic acid (CA)-loaded casein nanoparticles (CS NPs) via the Box–Behnken design (BBD) for potential…”
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Enhanced Allicin Cytotoxicity on HEPG‑2 Cells Using Glycyrrhetinic Acid Surface-Decorated Gelatin Nanoparticles by Ossama, Muhammed, Hathout, Rania M, Attia, Dalia A, Mortada, Nahed D

“…The cytotoxic potential of allicin was evaluated on different cancer cell lines, particularly, hepatic (HepG-2), breast (MCF-7), lung (A-549), and prostatic…”
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Microemulsion formulations for the transdermal delivery of testosterone by Hathout, Rania M., Woodman, Timothy J., Mansour, Samar, Mortada, Nahed D., Geneidi, Ahmed S., Guy, Richard H.

“…The objective was to develop a microemulsion formulation for the transdermal delivery of testosterone. Microemulsion formulations were prepared using oleic…”
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Polysaccharides-based nanocomplexes for the prolonged delivery of enoxaparin: In-vitro and in-vivo evaluation by Ibrahim, Shaimaa S., Osman, Rihab, Awad, Gehanne A.S., Mortada, Nahed D., Geneidi, Ahmed-Shawky

“…[Display omitted] Thromboprophylaxis and anticoagulant therapy face serious medical challenges in terms of how crucial it is to maintain therapeutic activity…”
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Travoprost Liquid Nanocrystals: An Innovative Armamentarium for Effective Glaucoma Therapy by El-Gendy, Mohamed A, Mansour, Mai, El-Assal, Mona I A, Ishak, Rania A H, Mortada, Nahed D

“…To date, the ophthalmic application of liquid crystalline nanostructures (LCNs) has not been thoroughly reconnoitered, yet they have been extensively used…”
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Anticancer effect of atorvastatin nanostructured polymeric micelles based on stearyl-grafted chitosan by Mekhail, George M., Kamel, Amany O., Awad, Gehanne A.S., Mortada, Nahed D.

“…The purpose of this study was to develop a new therapeutic approach for atorvastatin (ATV) adopting nanostructured polymeric micelles for its controlled…”
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Exploiting gelatin nanocarriers in the pulmonary delivery of methotrexate for lung cancer therapy by Abdelrady, Hend, Hathout, Rania M., Osman, Rihab, Saleem, Imran, Mortada, Nahed D.

“…Gelatin has many merits that encourage its use in the pulmonary delivery of anticancer drugs. It is a biodegradable denatured protein which possesses several…”
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Passive targeting and lung tolerability of enoxaparin microspheres for a sustained antithrombotic activity in rats by Ibrahim, Shaimaa S., Osman, Rihab, Mortada, Nahed D., Geneidy, Ahmed-Shawky, Awad, Gehanne A. S.

“…Pulmonary bed can retain microparticles (MP) larger than their capillaries' diameter, hence we offer a promising way for lung passive targeting following…”
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Glucospanlastics: innovative antioxidant and anticancer ascorbyl-2-glucoside vesicles for striking topical performance of repurposed itraconazole by Lamie, Caroline, Elmowafy, Enas, Attia, Dalia, Mortada, Nahed D

“…Presently, the development of functional derivatives exploiting biocompatible pharmaceutical materials has become a pressing demand. Among them,…”
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Role of edge activators and surface charge in developing ultradeformable vesicles with enhanced skin delivery by El Zaafarany, Ghada M., Awad, Gehanne A.S., Holayel, Samar M., Mortada, Nahed D.

“…Transfersomes are highly efficient edge activator (EA)-based ultraflexible vesicles capable of, non-invasively, trespassing skin by virtue of their high,…”
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Elaborated survey in the scope of nanocarriers engineering for boosting chemotherapy cytotoxicity: A meta-analysis study by Safwat, Sally, Hathout, Rania M., Ishak, Rania A., Mortada, Nahed D.

“…[Display omitted] Cancer is the prime cause of mortality throughout the world. Although the conventional chemotherapeutic agents damage the cancerous cells,…”
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Customizable resveratrol spray-dried micro-composites for inhalation as a promising contender for treatment of idiopathic pulmonary fibrosis by Ahmed, Sara, Mansour, Mai, Ishak, Rania A.H., Mortada, Nahed D.

“…[Display omitted] The past decades have witnessed tremendous expansion in utilization of plant-derived medicines as resveratrol (RES) in treating several…”
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Augmented cytotoxicity using the physical adsorption of Poloxamer 188 on allicin-loaded gelatin nanoparticles by Ossama, Muhammed, Hathout, Rania M, Attia, Dalia A, Mortada, Nahed D

“…The aim of this work was to study the effect of the physically adsorbed Poloxamer 188 coating polymer on the cytotoxic activity of allicin-loaded gelatin…”
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Anti-tumor efficacy of an integrated methyl dihydrojasmonate transdermal microemulsion system targeting breast cancer cells: In vitro and in vivo studies by Yehia, Rania, Hathout, Rania M., Attia, Dalia A., Elmazar, Mohamed M., Mortada, Nahed D.

“…[Display omitted] •Integration methyl dihydrojasmonate in microemulsion systems was achieved.•Transdermal fluxes of the oil were determined reaching a value of…”
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Diversifying the skin cancer-fighting worthwhile frontiers: How relevant are the itraconazole/ascorbyl palmitate nanovectors? by Lamie, Caroline, Elmowafy, Enas, Attia, Dalia A., Elmazar, Mohamed M., Mortada, Nahed D.

“…Fighting malignant neoplasms via repurposing existing drugs could be a welcome move for prosperous cancer remediations. In the current work, nanovehiculation…”
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Statins anticancer targeted delivery systems: re‐purposing an old molecule by Safwat, Sally, Ishak, Rania A., Hathout, Rania M., Mortada, Nahed D.

“…Objectives Exploring the use of statins as anticancer agents and exploiting different drug delivery systems in targeting these molecules to cancerous sites…”
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Nanostructured lipid carriers loaded with simvastatin: effect of PEG/glycerides on characterization, stability, cellular uptake efficiency and in vitro cytotoxicity by Safwat, Sally, Ishak, Rania A. H., Hathout, Rania M., Mortada, Nahed D.

“…Objective: The aim of this study is to evaluate the use of PEG/glycerides of different HLB; oleoyl macrogol-6-glycerides (Labrafil ® M 1944 CS) and…”
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A novel serum-stable liver targeted cytotoxic system using valerate-conjugated chitosan nanoparticles surface decorated with glycyrrhizin by El-Marakby, Eman M., Hathout, Rania M., Taha, Ismail, Mansour, Samar, Mortada, Nahed D.

“…Valerate-conjugated chitosan nanoparticles surface decorated with glycyrrhizin augments the cytotoxicity of ferulic acid and successfully targets it to the…”
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Augmented simvastatin cytotoxicity using optimized lipid nanocapsules: a potential for breast cancer treatment by Safwat, Sally, Hathout, Rania M., Ishak, Rania A., Mortada, Nahed D.

“…Context: We noticed paucity in exploiting solutol-based lipid nanocapsules in statins formulations though they carry all favorable properties that are needed…”
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