Search Results - "Morsy, Mohamed A."

On investigations of refractive indices and birefringence of fiber using duplicate and non‐duplicate micro‐interferograms of double refracting interferometer by El‐Morsy, Mohamed A.

“…The formula of refractive index of fiber considering the refraction has been reviewed. This formula is used to investigate the effect of refraction on the…”
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Fucoidan ameliorates steatohepatitis and insulin resistance by suppressing oxidative stress and inflammatory cytokines in experimental non-alcoholic fatty liver disease by Heeba, Gehan H, Morsy, Mohamed A

“…Highlights • Fucoidan alleviated high-fat diet-induced hepatic and metabolic disorders in rats. • Results suggest hypolipidemic, insulin sensitizing,…”
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Repurposing of FDA-approved antivirals, antibiotics, anthelmintics, antioxidants, and cell protectives against SARS-CoV-2 papain-like protease by Kandeel, Mahmoud, Abdelrahman, Alaa H. M., Oh-Hashi, Kentaro, Ibrahim, Abdelazim, Venugopala, Katharigatta N., Morsy, Mohamed A., Ibrahim, Mahmoud A. A.

“…SARS-CoV-2 or Coronavirus disease 19 (COVID-19) is a rapidly spreading, highly contagious, and sometimes fatal disease for which drug discovery and vaccine…”
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Experimental design, formulation and in vivo evaluation of a novel topical in situ gel system to treat ocular infections by Nair, Anroop B, Shah, Jigar, Jacob, Shery, Al-Dhubiab, Bandar E, Sreeharsha, Nagaraja, Morsy, Mohamed A, Gupta, Sumeet, Attimarad, Mahesh, Shinu, Pottathil, Venugopala, Katharigatta N

“…In situ gels have been extensively explored as ocular drug delivery system to enhance bioavailability and efficacy. The objective of present study was to…”
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Hidden pharmacological activities of valproic acid: A new insight by Singh, Dhirendra, Gupta, Sumeet, Verma, Inderjeet, Morsy, Mohamed A., Nair, Anroop B., Ahmed, Al-Shaimaa F.

“…Valproic acid (VPA) is an approved drug for managing epileptic seizures, bipolar disorders, and migraine. VPA has been shown to elevate the level of…”
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Lipid Nanoparticles as a Promising Drug Delivery Carrier for Topical Ocular Therapy-An Overview on Recent Advances by Jacob, Shery, Nair, Anroop B, Shah, Jigar, Gupta, Sumeet, Boddu, Sai H S, Sreeharsha, Nagaraja, Joseph, Alex, Shinu, Pottathil, Morsy, Mohamed A

“…Due to complicated anatomical and physical properties, targeted drug delivery to ocular tissues continues to be a key challenge for formulation scientists…”
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Computational Design, Synthesis, and Pharmacological Evaluation of Naproxen-Guaiacol Chimera for Gastro-Sparing Anti-Inflammatory Response by Selective COX2 Inhibition by Shinu, Pottathil, Sharma, Manu, Gupta, Girdhari Lal, Mujwar, Somdutt, Kandeel, Mahmoud, Kumar, Manish, Nair, Anroop B, Goyal, Manoj, Singh, Purna, Attimarad, Mahesh, Venugopala, Katharigatta N, Nagaraja, Sreeharsha, Telsang, Mallikarjun, Aldhubiab, Bandar E, Morsy, Mohamed A

“…The 4-allyl guaiacol is a natural phenolic molecule that has been widely studied for its antioxidant capacity against reactive-oxygen-species-mediated cellular…”
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Paeonol Attenuates Methotrexate-Induced Cardiac Toxicity in Rats by Inhibiting Oxidative Stress and Suppressing TLR4-Induced NF-κB Inflammatory Pathway by Zenhom, Nagwa M., Rifaai, Rehab A., Morsy, Mohamed A., Al-Taher, Abdulla, Abdel-Gaber, Seham A.

“…Methotrexate (MTX) is a commonly used chemotherapeutic agent. Oxidative stress and inflammation have been proved in the development of MTX toxicity. Paeonol is…”
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Nebivolol Ameliorates Cisplatin‐Induced Nephrotoxicity in Rats by Morsy, Mohamed A., Heeba, Gehan H.

“…Treatment with cisplatin is associated with dose‐limiting side effects, mainly nephrotoxicity. On the other hand, nebivolol, a β1‐adrenoceptor antagonist,…”
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Dry needling techniques as a treatment for improving disability and pain in patients with different types of headache: A systematic review and meta-analysis by Kandeel, Mahmoud, Morsy, Mohamed A., Al Khodair, Khalid M., Alhojaily, Sameer

“…Headaches, a widespread neuromuscular ailment, pose a significant burden on individuals and society, necessitating both pharmacological and non-pharmacological…”
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Diacerein ameliorates letrozole-induced polycystic ovarian syndrome in rats by Ibrahim, Yasmine F., Alorabi, Mohammed, Abdelzaher, Walaa Yehia, Toni, Nisreen DM, Thabet, Khaled, Hegazy, AbdelRahman, Bahaa, Haitham Ahmed, Batiha, Gaber El-Saber, Welson, Nermeen N., Morsy, Mohamed A., Venugopala, Katharigatta N., Abdel-Aziz, Asmaa Mohamed

“…Polycystic ovary syndrome (PCOS) is the most common gynaecological endocrine disease that causes anovulatory infertility. The current study aimed to explore…”
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Mechanisms of Thymoquinone Hepatorenal Protection in Methotrexate-Induced Toxicity in Rats by Hamouda, Azza H., Abdalla, Ahlam M., Morsy, Mohamed A., El-Sheikh, Azza A. K., Alhaider, Ibrahim A.

“…To investigate mechanisms by which thymoquinone (TQ) can prevent methotrexate- (MTX-) induced hepatorenal toxicity, TQ (10 mg/kg) was administered orally for…”
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Clarithromycin Solid Lipid Nanoparticles for Topical Ocular Therapy: Optimization, Evaluation and In Vivo Studies by Nair, Anroop B, Shah, Jigar, Al-Dhubiab, Bandar E, Jacob, Shery, Patel, Snehal S, Venugopala, Katharigatta N, Morsy, Mohamed A, Gupta, Sumeet, Attimarad, Mahesh, Sreeharsha, Nagaraja, Shinu, Pottathil

“…Solid lipid nanoparticles (SLNs) are being extensively exploited as topical ocular carrier systems to enhance the bioavailability of drugs. This study…”
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Mesenchymal Stem Cell-Derived Extracellular Vesicles: An Emerging Diagnostic and Therapeutic Biomolecules for Neurodegenerative Disabilities by Kandeel, Mahmoud, Morsy, Mohamed A, Alkhodair, Khalid M, Alhojaily, Sameer

“…Mesenchymal stem cells (MSCs) are a type of versatile adult stem cells present in various organs. These cells give rise to extracellular vesicles (EVs)…”
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ADVANCES OF NON-IRON METAL NANOPARTICLES IN BIOMEDICINE by Nair, Anroop B., Morsy, Mohamed A., Shinu, Pottathil, Kotta, Sabna, Chandrasekaran, Mithra, Tahir, Abu

“…Metal nanoparticles (MNPs) comprise of nanoparticles originating from metallic elements with additional properties inherent to metal ions. MNPs found…”
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Canagliflozin, an SGLT-2 inhibitor, ameliorates acetic acid-induced colitis in rats through targeting glucose metabolism and inhibiting NOX2 by Morsy, Mohamed A., Khalaf, Hanaa M., Rifaai, Rehab A., Bayoumi, Asmaa M.A., Khalifa, Esraa M.M.A., Ibrahim, Yasmine F.

“…Inflammatory bowel disease is defined as chronic noninfectious inflammation of the gastrointestinal tract, including ulcerative colitis and Crohn’s disease…”
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Protective Effect of Spirulina platensis Extract against Dextran-Sulfate-Sodium-Induced Ulcerative Colitis in Rats by Morsy, Mohamed A, Gupta, Sumeet, Nair, Anroop B, Venugopala, Katharigatta N, Greish, Khaled, El-Daly, Mahmoud

“…Inflammatory bowel disease is a multifactorial inflammatory condition. This study aimed to test the protective effects of against ulcerative colitis (UC). UC…”
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Ameliorative Effect of Dabigatran on CFA-Induced Rheumatoid Arthritis via Modulating Kallikrein-Kinin System in Rats by Youssef, Mahmoud E., Abdel-Reheim, Mustafa A., Morsy, Mohamed A., El-Daly, Mahmoud, Atwa, Gamal M. K., Yahya, Galal, Cavalu, Simona, Saber, Sameh, Ahmed Gaafar, Ahmed Gaafar

“…Rheumatoid arthritis is an autoimmune disease that affects joints, leading to swelling, inflammation, and dysfunction in the joints. Recently, research efforts…”
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Protective mechanisms of telmisartan against hepatic ischemia/reperfusion injury in rats may involve PPARγ-induced TLR4/NF-κB suppression by Morsy, Mohamed A., Abdel-Gaber, Seham A., Rifaai, Rehab A., Mohammed, Mostafa M., Nair, Anroop B., Abdelzaher, Walaa Yehia

“…Hepatic ischemia-reperfusion (I/R) is an important cause of liver damage in many clinical situations. Toll-like receptor 4 (TLR4)/nuclear factor-kappa B…”
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Paeonol Protects against Methotrexate Hepatotoxicity by Repressing Oxidative Stress, Inflammation, and Apoptosis—The Role of Drug Efflux Transporters by Morsy, Mohamed A, Abdel-Latif, Rania, Hafez, Sara Mohamed Naguib Abdel, Kandeel, Mahmoud, Abdel-Gaber, Seham A

“…Methotrexate (MTX) is an effective chemotherapeutic agent against a wide range of tumors and autoimmune diseases; however, hepatotoxicity limits its clinical…”
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