Search Results - "Morse, Sophie V"

Rapid short-pulses of focused ultrasound and microbubbles deliver a range of agent sizes to the brain by Lim Kee Chang, William, Chan, Tiffany G., Raguseo, Federica, Mishra, Aishwarya, Chattenton, Dani, de Rosales, Rafael T. M., Long, Nicholas J., Morse, Sophie V.

“…Focused ultrasound and microbubbles can non-invasively and locally deliver therapeutics and imaging agents across the blood–brain barrier. Uniform treatment…”
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Targeted Delivery of DNA‐Au Nanoparticles across the Blood–Brain Barrier Using Focused Ultrasound by Chan, Tiffany G., Morse, Sophie V., Copping, Matthew J., Choi, James J., Vilar, Ramon

“…Nanoparticles have been widely studied as versatile platforms for in vivo imaging and therapy. However, their use to image and/or treat the brain is limited,…”
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Using focused ultrasound to modulate microglial structure and function by Grewal, Sarina, Gonçalves de Andrade, Elisa, Kofoed, Rikke Hahn, Matthews, Paul M, Aubert, Isabelle, Tremblay, Marie-Ève, Morse, Sophie V

“…Transcranial focused ultrasound (FUS) has the unique ability to target regions of the brain with high spatial precision, in a minimally invasive manner…”
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Liposome delivery to the brain with rapid short-pulses of focused ultrasound and microbubbles by Morse, Sophie V., Mishra, Aishwarya, Chan, Tiffany G., T. M. de Rosales, Rafael, Choi, James J.

“…Liposomes are clinically used drug carriers designed to improve the delivery of drugs to specific tissues while minimising systemic distribution. However,…”
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Rapid Short-pulse Ultrasound Delivers Drugs Uniformly across the Murine Blood-Brain Barrier with Negligible Disruption by Morse, Sophie V, Pouliopoulos, Antonios N, Chan, Tiffany G, Copping, Matthew J, Lin, Julien, Long, Nicholas J, Choi, James J

“…Background Previous work has demonstrated that drugs can be delivered across the blood-brain barrier by exposing circulating microbubbles to a sequence of long…”
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Modulation of amyloid-β aggregation by metal complexes with a dual binding mode and their delivery across the blood-brain barrier using focused ultrasound by Chan, Tiffany G, Ruehl, Carmen L, Morse, Sophie V, Simon, Michelle, Rakers, Viktoria, Watts, Helena, Aprile, Francesco A, Choi, James J, Vilar, Ramon

“…One of the key hallmarks of Alzheimer's disease is the aggregation of the amyloid-β peptide to form fibrils. Consequently, there has been great interest in…”
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Successful synthesis of a glial‐specific blood–brain barrier shuttle peptide following a fragment condensation approach on a solid‐phase resin by Al Musaimi, Othman, Morse, Sophie V., Lombardi, Lucia, Serban, Simona, Basso, Alessandra, Williams, Daryl R.

“…Successful manual synthesis of the TD2.2 peptide acting as a blood–brain barrier shuttle was achieved. TD2.2 was successfully synthesised by sequential…”
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Inhibition of the angiotensin II type 2 receptor AT2R is a novel therapeutic strategy for glioblastoma by Perryman, Richard, Renziehausen, Alexander, Shaye, Hamidreza, Kostagianni, Androniki D, Tsiailanis, Antonis D, Thorne, Thomas, Chatziathanasiadou, Maria V, Sivolapenko, Gregory B, El Mubarak, Mohamed Ahmed, Han, Gye Won, Zarzycka, Barbara, Katritch, Vsevolod, Lebon, Guillaume, Nigro, Cristiana Lo, Lattanzio, Laura, Morse, Sophie V, Choi, James J, O'Neill, Kevin, Kanaki, Zoi, Klinakis, Apostolos, Crook, Tim, Cherezov, Vadim, Tzakos, Andreas G, Syed, Nelofer

“…Glioblastoma (GBM) is an aggressive malignant primary brain tumor with limited therapeutic options. We show that the angiotensin II (AngII) type 2 receptor…”
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Imaging With Therapeutic Acoustic Wavelets-Short Pulses Enable Acoustic Localization When Time of Arrival is Combined With Delay and Sum by Davies, Harry J., Morse, Sophie V., Copping, Matthew J., Sujarittam, Krit, Bourgin, Victor D., Tang, Meng-Xing, Choi, James J.

“…Passive acoustic mapping (PAM) is an algorithm that reconstructs the location of acoustic sources using an array of receivers. This technique can monitor…”
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Inhibition of the angiotensin II type 2 receptor AT 2 R is a novel therapeutic strategy for glioblastoma by Perryman, Richard, Renziehausen, Alexander, Shaye, Hamidreza, Kostagianni, Androniki D, Tsiailanis, Antonis D, Thorne, Thomas, Chatziathanasiadou, Maria V, Sivolapenko, Gregory B, El Mubarak, Mohamed Ahmed, Han, Gye Won, Zarzycka, Barbara, Katritch, Vsevolod, Lebon, Guillaume, Lo Nigro, Cristiana, Lattanzio, Laura, Morse, Sophie V, Choi, James J, O'Neill, Kevin, Kanaki, Zoi, Klinakis, Apostolos, Crook, Tim, Cherezov, Vadim, Tzakos, Andreas G, Syed, Nelofer

“…Glioblastoma (GBM) is an aggressive malignant primary brain tumor with limited therapeutic options. We show that the angiotensin II (AngII) type 2 receptor (AT…”
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Doppler Passive Acoustic Mapping by Pouliopoulos, Antonios N., Smith, Cameron A. B., Bezer, James H., El Ghamrawy, Ahmed, Sujarittam, Krit, Bouldin, Charlotte J., Morse, Sophie V., Tang, Meng-Xing, Choi, James J.

“…In therapeutic ultrasound using microbubbles, it is essential to drive the microbubbles into the correct type of activity and the correct location to produce…”
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Neuron labeling with rhodamine-conjugated Gd-based MRI contrast agents delivered to the brain via focused ultrasound by Morse, Sophie V, Boltersdorf, Tamara, Harriss, Bethany I, Chan, Tiffany G, Baxan, Nicoleta, Jung, Hee Seok, Pouliopoulos, Antonios N, Choi, James J, Long, Nicholas J

“…Gadolinium-based magnetic resonance imaging contrast agents can provide information regarding neuronal function, provided that these agents can cross the…”
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In vivo delivery of a fluorescent FPR2/ALX-targeted probe using focused ultrasound and microbubbles to image activated microglia by Morse, Sophie V., Boltersdorf, Tamara, Chan, Tiffany G., Gavins, Felicity N. E., Choi, James J., Long, Nicholas J.

“…To image activated microglia, a small-molecule FPR2/ALX-targeted fluorescent probe was locally delivered into the brain using focused ultrasound and…”
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Notice of Removal: Rapid short-pulse (RaSP) sequences improve the distribution of drug delivery to the brain in vivo by Morse, Sophie V., Pouliopoulos, Antonios N., Chan, Tiffany, Lin, Julien, Copping, Matthew, Long, Nicholas J., Choi, James J.

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