Search Results - "Morrow, Benjamin J."
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Two-Photon Fluorescence Microscopy Imaging of Cellular Oxidative Stress Using Profluorescent Nitroxides
Published in Journal of the American Chemical Society (14-03-2012)“…A range of varying chromophore nitroxide free radicals and their nonradical methoxyamine analogues were synthesized and their linear photophysical properties…”
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2
Experimental and Theoretical Studies of the Redox Potentials of Cyclic Nitroxides
Published in Journal of organic chemistry (05-09-2008)“…The redox potentials of 25 cyclic nitroxides from four different structural classes (pyrrolidine, piperidine, isoindoline, and azaphenalene) were determined…”
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3
Fragment screening for a protein-protein interaction inhibitor to WDR5
Published in Structural dynamics (Melville, N.Y.) (01-11-2019)“…The WD40-repeat protein WDR5 scaffolds various epigenetic writers and is a critical component of the mammalian SET/MLL histone methyltransferase complex…”
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Pro-fluorescent mitochondria-targeted real-time responsive redox probes synthesised from carboxy isoindoline nitroxides: Sensitive probes of mitochondrial redox status in cells
Published in Free radical biology & medicine (20-11-2018)“…Here we describe new fluorescent probes based on fluorescein and rhodamine that provide reversible, real-time insight into cellular redox status. The new…”
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5
Preparation and stabilization of monodisperse colloidal gold by reduction with aminodextran
Published in Journal of colloid and interface science (01-07-2009)“…Stable concentrated dispersions of monodisperse gold nanoparticles were synthesized by using diethylaminoethyl-dextran as reductant and stabilizer. Stable…”
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Evidence for the in Vitro Bioactivation of Aminopyrazole Derivatives: Trapping Reactive Aminopyrazole Intermediates Using Glutathione Ethyl Ester in Human Liver Microsomes
Published in Chemical research in toxicology (21-09-2015)“…Drug-induced toxicity is a leading cause of drug withdrawal from clinical development and clinical use and represents a major impediment to the development of…”
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A novel profluorescent nitroxide as a sensitive probe for the cellular redox environment
Published in Free radical biology & medicine (01-07-2010)“…Changes to the redox status of biological systems have been implicated in the pathogenesis of a wide variety of disorders. Sensitive quantification of these…”
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