Search Results - "Morrone, Maurílio"

Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas by Zanotto-Filho, Alfeu, Braganhol, Elizandra, Klafke, Karina, Figueiró, Fabrício, Terra, Sílvia Resende, Paludo, Francis Jackson, Morrone, Maurílio, Bristot, Ivi Juliana, Battastini, Ana Maria, Forcelini, Cassiano Mateus, Bishop, Alexander James Roy, Gelain, Daniel Pens, Moreira, José Cláudio Fonseca

“…Abstract Glioblastoma is a devastating primary brain tumor resistant to conventional therapies. In this study, we tested the efficacy of combining temozolomide…”
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Guarana (Paullinia cupana Mart.) alters gut microbiota and modulates redox status, partially via caffeine in Wistar rats by Kleber Silveira, Alexandre, Moresco, Karla Suzana, Mautone Gomes, Henrique, Silva Morrone, Maurílio, Kich Grun, Lucas, Pens Gelain, Daniel, Mattos Pereira, Leandro, Giongo, Adriana, Rodrigues De Oliveira, Rafael, Fonseca Moreira, José Cláudio

“…Microbiota alterations are observed in pathological conditions, and their regulation is a subject of great interest. Gut microbes are affected by diet, and…”
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Antioxidant and Anti-Inflammatory Properties of Anacardium occidentale Leaf Extract by Dalmolin, Rodrigo Juliani Siqueira, Pasquali, Matheus Augusto de Bittencourt, Moreira, José Cláudio Fonseca, Zucolotto, Silvana Maria, Camillo, Christina da Silva, Amarante, Maria do Socorro Medeiros, D’Oliveira Albanus, Ricardo, Morrone, Maurilio da Silva, de Oliveira, Juliana Medeiros, Souza, Natália Cabral, Gelain, Daniel Pens

“…In tropical America, principally in Northeastern Brazil, the leaf extract of Anacardium occidentale is traditionally used for treatment of different diseases…”
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Vitamin A supplementation in rats under pregnancy and nursing induces behavioral changes and oxidative stress upon striatum and hippocampus of dams and their offspring by Schnorr, Carlos Eduardo, da Silva Morrone, Maurílio, Simões-Pires, André, da Rocha, Ricardo Fagundes, Behr, Guilherme Antônio, Moreira, José Cláudio Fonseca

“…Abstract Vitamin A is important for both development and maintenance of adult brain homeostasis. However, excessive vitamin A exposure has been linked to…”
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Dietary n-3 polyunsaturated fatty acids revert renal responses induced by a combination of 2 protocols that increase the amounts of advanced glycation end product in rats by de Assis, Adriano M, Rech, Anderson, Longoni, Aline, da Silva Morrone, Maurílio, de Bittencourt Pasquali, Matheus A, Perry, Marcos L.S, Souza, Diogo O, Moreira, José C.F

“…Abstract Renal dysfunction is a severe complication that is caused by diabetes mellitus. Many factors associate the progression of this complication with high…”
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Increased 3-nitrotyrosine levels in mitochondrial membranes and impaired respiratory chain activity in brain regions of adult female rats submitted to daily vitamin A supplementation for 2 months by de Oliveira, Marcos Roberto, Lorenzi, Rodrigo, Schnorr, Carlos Eduardo, Morrone, Maurílio, Moreira, José Cláudio Fonseca

“…Highlights ► We are demonstrating that vitamin A supplementation at low doses induces a redox dysfunction in female rat brain regions. ► Such treatment induced…”
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Early abstinence of crack-cocaine is effective to attenuate oxidative stress and to improve antioxidant defences by Zaparte, Aline, Viola, Thiago W., Grassi-Oliveira, Rodrigo, da Silva Morrone, Maurilio, Moreira, José C., Bauer, Moisés E.

“…Rationale Preclinical studies have shown that cocaine exposure and withdrawal are associated with cellular oxidative stress damage. However, the impact of…”
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Oral administration of curcumin relieves behavioral alterations and oxidative stress in the frontal cortex, hippocampus, and striatum of ovariectomized Wistar rats by Da Silva Morrone, Maurilio, Schnorr, Carlos Eduardo, Behr, Guilherme Antônio, Gasparotto, Juciano, Bortolin, Rafael Calixto, Moresco, Karla Suzana, Bittencourt, Leonardo, Zanotto-Filho, Alfeu, Gelain, Daniel Pens, Moreira, José Cláudio Fonseca

“…Menopause occurs gradually and is characterized by increased susceptibility to developing mood disorders. Several studies have suggested treatments based on…”
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Passiflora manicata (Juss.) aqueous leaf extract protects against reactive oxygen species and protein glycation in vitro and ex vivo models by da Silva Morrone, Maurilio, de Assis, Adriano Martimbianco, da Rocha, Ricardo Fagundes, Gasparotto, Juciano, Gazola, Andressa Córneo, Costa, Geison Modesti, Zucolotto, Silvana Maria, Castellanos, Leonardo H., Ramos, Freddy A., Schenkel, Eloir Paulo, Reginatto, Flávio Henrique, Gelain, Daniel Pens, Moreira, José C.F.

“…•Passiflora manicata possess C-glycosylflavonoids in your crude extract.•PMLE is a potential scavenger of peroxyl radicals in vitro.•P. manicata protect…”
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The impact of childhood maltreatment on redox state: Relationship with oxidative damage and antioxidant defenses in adolescents with no psychiatric disorder by do Prado, Carine Hartmann, Grassi-Oliveira, Rodrigo, Wieck, Andréa, Zaparte, Aline, Filho, Ledo Daruy, da Silva Morrone, Maurilio, Moreira, José C., Bauer, Moisés Evandro

“…•Early-life stress (ELS) was associated with increased protein carbonylation.•Adolescents with ELS had higher SOD levels, TRAP kinetics but reduced GPx.•ELS…”
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Supplementation of adult rats with moderate amounts of β-carotene modulates the redox status in plasma without exerting pro-oxidant effects in the brain: a safer alternative to food fortification with vitamin A? by Schnorr, Carlos Eduardo, Morrone, Maurilio da Silva, Simões-Pires, André, Bittencourt, Leonardo da Silva, Zeidán-Chuliá, Fares, Moreira, José Cláudio Fonseca

“…Despite the antioxidant potential of vitamin A, recent studies reported that chronic retinol ester supplementation can also exert pro-oxidant effects and…”
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Effects of different products of peach (Prunus persica L. Batsch) from a variety developed in southern Brazil on oxidative stress and inflammatory parameters in vitro and ex vivo by Gasparotto, Juciano, Somensi, Nauana, Bortolin, Rafael Calixto, Moresco, Karla Suzana, Girardi, Carolina Saibro, Klafke, Karina, Rabelo, Thallita Kelly, Morrone, Maurilio Da Silva, Vizzotto, Márcia, Maria do Carmo Bassols Raseira, Moreira, José Claudio Fonseca, Gelain, Daniel Pens

“…Antioxidant, anti-glycation and anti-inflammatory activities of fresh and conserved peach fruits (Prunus persica L. Batsch) were compared. Fresh peach pulps,…”
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Effects of Freeze-Thaw and Storage on Enzymatic Activities, Protein Oxidative Damage, and Immunocontent of the Blood, Liver, and Brain of Rats by Bortolin, Rafael Calixto, Gasparotto, Juciano, Vargas, Amanda Rodrigues, da Silva Morrone, Maurilio, Kunzler, Alice, Henkin, Bernardo Saldanha, Chaves, Paloma Rodrigues, Roncato, Sabrina, Gelain, Daniel Pens, Moreira, José Cláudio Fonseca

“…Most scientific studies are too long to be conducted in a single day or even in a few days. Thus, there is a need to store samples for subsequent…”
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Extracellular HSP70 Activates ERK1/2, NF-kB and Pro-Inflammatory Gene Transcription Through Binding with RAGE in A549 Human Lung Cancer Cells by Somensi, Nauana, Brum, Pedro Ozorio, de Miranda Ramos, Vitor, Gasparotto, Juciano, Zanotto-Filho, Alfeu, Rostirolla, Diana Carolina, da Silva Morrone, Maurilio, Moreira, José Claudio Fonseca, Pens Gelain, Daniel

“…Background/Aims: Heat shock protein 70 (HSP70) has been recently described with extracellular actions, where it is actively released in inflammatory…”
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The effects of vitamin A supplementation to rats during gestation and lactation upon redox parameters: Increased oxidative stress and redox modulation in mothers and their offspring by Schnorr, Carlos Eduardo, Morrone, Maurilio Da Silva, Weber, Maria Helena, Lorenzi, Rodrigo, Behr, Guilherme Antônio, Moreira, José Cláudio Fonseca

“…► Vitamin A induced oxidative damage in uterus, ovaries, and plasma of dams. ► Glutathione-S-transferase activity was modulated by vitamin A supplementation. ►…”
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Moderate beer consumption promotes silymarin-like redox status without affecting the liver integrity in vivo by Caon, Glauco, Morrone, Maurílio, Feistauer, Lucas, Sganzerla, Daniel, Moreira, José C.F.

“…Moderate beer intake can have beneficial effects against chronic diseases due to the flavonoids in the hops. The present study investigated the effect of…”
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Supplementation with Achyrocline satureioides Inflorescence Extracts to Pregnant and Breastfeeding Rats Induces Tissue-Specific Changes in Enzymatic Activity and Lower Neonatal Survival by Moresco, Karla Suzana, Silveira, Alexandre Kleber, Schnorr, Carlos Eduardo, Zeidán-Chuliá, Fares, Bortolin, Rafael Calixto, Bittencourt, Leonardo da Silva, Mingori, Moara, Heimfarth, Luana, Rabelo, Thallita Kelly, Morrone, Maurilio da Silva, Carini, Juliana Poglia, Gelain, Daniel Pens, Bassani, Valquiria Linck, Moreira, José Cláudio Fonseca

“…(AS, family Asteraceae) is a plant widely used in traditional medicine for stomach, digestive, and gastrointestinal disorders during pregnancy. Studies…”
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BRCA-1 depletion impairs pro-inflammatory polarization and activation of RAW 264.7 macrophages in a NF-κB-dependent mechanism by Morrone, Maurilio da Silva, Somensi, Nauana, Franz, Lucas, Ramos, Vitor de Miranda, Gasparotto, Juciano, da Rosa, Helen Taís, Sartori, Marcelo, Figueiró, Fabrício, Gelain, Daniel Pens, Zanotto-Filho, Alfeu, Moreira, José Cláudio Fonseca

“…BRCA-1 is a nuclear protein involved in DNA repair, transcriptional regulation, and cell cycle control. Its involvement in other cellular processes has been…”
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Curcumin Supplementation Decreases Intestinal Adiposity Accumulation, Serum Cholesterol Alterations, and Oxidative Stress in Ovariectomized Rats by Gelain, Daniel Pens, Fonseca Moreira, José Cláudio, Zanotto-Filho, Alfeu, Saldanha Henkin, Bernardo, da Boit Martinello, Katia, Bortolin, Rafael Calixto, Gasparotto, Juciano, Antonio Behr, Guilherme, Schnorr, Carlos Eduardo, Morrone, Maurilio da Silva, Rabello, Thallita Kelly

“…The aim of this study was to investigate the potential of curcumin oral supplementation (50 and 100 mg/Kg/day, for 30 days) in circumventing…”
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BRCA-1 depletion impairs pro-inflammatory polarization and activation of RAW 264.7 macrophages in a NF-[kappa]B-dependent mechanism by Morrone, Maurilio da Silva, Somensi, Nauana, Franz, Lucas, Ramos, Vitor de Miranda, Gasparotto, Juciano, da Rosa, Helen Taís, Sartori, Marcelo

“…BRCA-1 is a nuclear protein involved in DNA repair, transcriptional regulation, and cell cycle control. Its involvement in other cellular processes has been…”
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