Search Results - "Morrone, B."

Synergistic effects of celecoxib and bupropion in a model of chronic inflammation-related depression in mice by Maciel, Izaque S, Silva, Rodrigo B M, Morrone, Fernanda B, Calixto, João B, Campos, Maria M

“…This study was aimed to characterize the depression-like behaviour in the classical model of chronic inflammation induced by Complete Freund's Adjuvant (CFA)…”
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Hydrothermal Carbonization: A Pilot-Scale Reactor Design for Bio-waste and Sludge Pre-treatment by Zaccariello, L., Battaglia, D., Morrone, B., Mastellone, M. L.

“…The purpose of the paper is to illustrate the basis of the design of a pilot-scale reactor built to convert putrescent and high-water content biowaste into a…”
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Intercomparison of radiosensitization induced by gold and iron oxide nanoparticles in human glioblastoma cells irradiated by 6 MV photons by Guerra, Danieli B., Oliveira, Elisa M. N., Sonntag, Amanda R., Sbaraine, Patricia, Fay, Andre P., Morrone, Fernanda B., Papaléo, Ricardo M.

“…In this work, an intercomparison of sensitization effects produced by gold (GNP) and dextran-coated iron oxide (SPION-DX) nanoparticles in M059J and U87 human…”
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The role of P2X7 purinergic receptors in inflammatory and nociceptive changes accompanying cyclophosphamide‐induced haemorrhagic cystitis in mice by Martins, JP, Silva, RBM, Coutinho‐Silva, R, Takiya, CM, Battastini, AMO, Morrone, FB, Campos, MM

“…BACKGROUND AND PURPOSE ATP is released in response to cellular damage, and P2X7 receptors have an essential role in the onset and maintenance of pathological…”
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Purinergic Cooperation Between P2Y2 and P2X7 Receptors Promote Cutaneous Leishmaniasis Control: Involvement of Pannexin-1 and Leukotrienes by Thorstenberg, Maria Luiza, Rangel Ferreira, Marcos Vinícius, Amorim, Natália, Canetti, Claudio, Morrone, Fernanda B., Alves Filho, José Carlos, Coutinho-Silva, Robson

“…The release of damage-associated molecular patterns, including uridine triphosphate (UTP) and adenosine triphosphate (ATP) to the extracellular milieu is a key…”
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Effects of the compounds resveratrol, rutin, quercetin, and quercetin nanoemulsion on oxaliplatin-induced hepatotoxicity and neurotoxicity in mice by Schwingel, Tania E., Klein, Caroline P., Nicoletti, Natalia F., Dora, Cristiana L., Hadrich, Gabriela, Bica, Cláudia G., Lopes, Tiago G., da Silva, Vinicius Duval, Morrone, Fernanda B.

“…Oxaliplatin (OXA) is a platinum compound widely used in the treatment of some solid tumors, especially colorectal cancer. Despite its usefulness,…”
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Evaluation of nuclear NF-κB, transglutaminase2, and ERCC1 as predictors of platinum resistance in testicular tumors by Azambuja, Alan A., Engroff, Paula, Silva, Bruna T., Zorzetti, Roberta C. S., Morrone, Fernanda B.

“…ABSTRACT Purpose: Testicular germ cells tumor (TGCT) are associated with a high cure rate and are treated with platinum-based chemotherapy. However, a group of…”
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Pharmacological blockage and P2X7 deletion hinder aversive memories: Reversion in an enriched environment by Campos, R.C, Parfitt, G.M, Polese, C.E, Coutinho-Silva, R, Morrone, F.B, Barros, D.M

“…Highlights • P2X7 receptor deletion impaired two memory tasks in rodent models. • Pharmacological blockade of P2X7 receptor hindered conditioned memory. •…”
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Implication of purinergic P2X7 receptor in M. tuberculosis infection and host interaction mechanisms: A mouse model study by Santos, André A, Rodrigues-Junior, Valnês, Zanin, Rafael F, Borges, Thiago J, Bonorino, Cristina, Coutinho-Silva, Robson, Takyia, Christina M, Santos, Diógenes S, Campos, Maria M, Morrone, Fernanda B

“…Abstract In the present study, we analyzed the role of purinergic P2X7 receptor in Mycobacterium tuberculosis infection and host interaction mechanisms in…”
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Effects of indomethacin‐loaded nanocapsules in experimental models of inflammation in rats by Bernardi, A, Zilberstein, ACCV, Jäger, E, Campos, MM, Morrone, FB, Calixto, JB, Pohlmann, AR, Guterres, SS, Battastini, AMO

“…Background and purpose:  The effects of systemic treatment with indomethacin‐loaded nanocapsules (IndOH‐NC) were compared with those of free indomethacin…”
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Selective NTPDase2 expression modulates in vivo rat glioma growth by Braganhol, Elizandra, Morrone, Fernanda B., Bernardi, Andressa, Huppes, Daiane, Meurer, Luise, Edelweiss, Maria Isabel A., Lenz, Guido, Wink, Márcia R., Robson, Simon C., Battastini, Ana Maria O.

“…The ectonucleoside triphosphate diphosphohydrolases (E‐NTPDases) are a family of ectoenzymes that hydrolyze extracellular nucleotides, thereby modulating…”
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Spinal blockage of P/Q‐ or N‐type voltage‐gated calcium channels modulates functional and symptomatic changes related to haemorrhagic cystitis in mice by Silva, R B M, Sperotto, N D M, Andrade, E L, Pereira, T C B, Leite, C E, Souza, A H, Bogo, M R, Morrone, F B, Gomez, M V, Campos, M M

“…Background and Purpose Spinal voltage‐gated calcium channels (VGCCs) are pivotal regulators of painful and inflammatory alterations, representing attractive…”
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Efficacy and gastrointestinal tolerability of ML3403, a selective inhibitor of p38 MAP kinase and CBS-3595, a dual inhibitor of p38 MAP kinase and phosphodiesterase 4 in CFA-induced arthritis in rats by Koch, Diana A., Silva, Rodrigo B. M., de Souza, Alessandra H., Leite, Carlos E., Nicoletti, Natália F., Campos, Maria M., Laufer, Stefan, Morrone, Fernanda B.

“…Objective. Mitogen-activated protein kinase (MAPK) p38 inhibitors have entered the clinical phase, although many of them have failed due to high toxicity and…”
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Outcome of Periapical Lesions in a Rat Model of Type 2 Diabetes: Refractoriness to Systemic Antioxidant Therapy by Wolle, Carlos Frederico B., MSc, Zollmann, Luciana A., BS, Bairros, Patrícia O., BS, Etges, Adriana, PhD, Leite, Carlos E., MSc, Morrone, Fernanda B., PhD, Campos, Maria M., PhD

“…Abstract Introduction This study evaluated the development of periapical lesions in a rat model of type 2 diabetes and assessed the potential actions of the…”
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Effects of the hydroalcoholic extract of Phyllanthus niruri and its isolated compounds on cyclophosphamide-induced hemorrhagic cystitis in mouse by Boeira, Vinícios T., Leite, Carlos E., Santos, André A., Edelweiss, Maria I., Calixto, João B., Campos, Maria M., Morrone, Fernanda B.

“…The effects of Phyllanthus niruri hydroalcoholic extract and the isolated compounds quercetin, rutin, and gallic acid were examined in the mouse model of…”
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Different Methods to Identify Pain after Routine Surgical Castration of Equine Stallions: Composite Pain Scale, Facial Expressions, Faecal Glucocorticoid Metabolites and Plasma Cytokines by Stucke, D., Hall, S., Morrone, B., Große Ruse, M., Lebelt, D.

“…Reasons for performing study Lack of ‘gold standard’ for pain assessment in horses. Objectives To assess different approaches of quantifying pain in horses…”
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P2X7 receptor is required for neutrophil accumulation in a mouse model of irritant contact dermatitis by da Silva, Gabriela L., Sperotto, Nathalia D. M., Borges, Thiago J., Bonorino, Cristina, Takyia, Cristina M., Coutinho-Silva, Robson, Campos, Maria M., Zanin, Rafael F., Morrone, Fernanda B.

“…Irritant contact dermatitis (ICD) is an inflammatory reaction caused by chemical toxicity on the skin. The P2X7 receptor (P2X7R) is a key mediator of cytokine…”
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In vivo glioblastoma growth is reduced by apyrase activity in a rat glioma model by Morrone, Fernanda B, Oliveira, Diogo L, Gamermann, Patrícia, Stella, Joseli, Wofchuk, Suzana, Wink, Márcia R, Meurer, Luise, Edelweiss, Maria Isabel A, Lenz, Guido, Battastini, Ana Maria O

“…ATP is an important signalling molecule in the peripheral and central nervous system. Both glioma growth and tumor resection induces cell death, thus…”
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Effects of the compounds MV8608 and MV8612 obtained from Mandevilla velutina in the model of hemorrhagic cystitis induced by cyclophosphamide in rats by Santos, André A., Leal, Paulo C., Edelweiss, Maria I. A., Lopes, Tiago Giuliani, Calixto, João B., Morrone, Fernanda B., Campos, Maria M.

“…Hemorrhagic cystitis (HC) is a common side effect observed in patients under chemotherapy with cyclophosphamide (CYP). The urotoxic side effects of CYP are…”
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Calcium Channels and Associated Receptors in Malignant Brain Tumor Therapy by Morrone, Fernanda B, Gehring, Marina P, Nicoletti, Natália F

“…Malignant brain tumors are highly lethal and aggressive. Despite recent advances in the current therapies, which include the combination of surgery and…”
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