Search Results - "Morrissey, Robert L."

Reproductive toxicity assessment of chronic dietary exposure to soy isoflavones in male rats by Faqi, Ali S, Johnson, William D, Morrissey, Robert L, McCormick, David L

“…Epidemiologic and experimental data suggest that consumption of diets that are rich in isoflavones may decrease cancer risk in the breast, prostate, and other…”
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Resveratrol-Associated Renal Toxicity by Crowell, James A., Korytko, Peter J., Morrissey, Robert L., Booth, Tristan D., Levine, Barry S.

“…Resveratrol, (3,5,4′-trihydoxystilbene) a compound found in grapes, mulberries, and peanuts, has antimycotic, antiviral, and beneficial cardiovascular and…”
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Modulation of hepatic and renal drug metabolizing enzyme activities in rats by subchronic administration of farnesol by Horn, Thomas L., Long, Lina, Cwik, Michael J., Morrissey, Robert L., Kapetanovic, Izet M., McCormick, David L.

“…Farnesol demonstrates antitumor activity in several animal models for human cancer and was being considered for development as a cancer chemopreventive agent…”
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Integration of in vivo and in vitro approaches to characterize the toxicity of Antalarmin, a corticotropin-releasing hormone receptor antagonist by Horn, Thomas L, Harder, J. Brooks, Johnson, William D, Curry, Patrick T, Parchment, Ralph E, Morrissey, Robert L, Mellick, Paul W, Calis, Karim A, Gold, Philip W, Rice, Kenner C, Contoreggi, Carlo, Charney, Dennis S, Cizza, Giovanni, Glaze, Elizabeth R, Tomaszewski, Joseph E, McCormick, David L

“…Abstract Non-clinical studies were conducted to evaluate the toxicity of Antalarmin, a corticotropin-releasing hormone type 1 receptor antagonist being…”
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TOXICOLOGIC EVALUATION OF HUMECTANTS ADDED TO CIGARETTE TOBACCO: 13-WEEK SMOKE INHALATION STUDY OF GLYCERIN AND PROPYLENE GLYCOL IN FISCHER 344 RATS by Heck, J. Daniel, Gaworski, Charles L., Rajendran, Narayanan, Morrissey, Robert L.

“…Glycerin (CAS no. 56-81-5) and propylene glycol (CAS no. 57-55-6) are commonly used as humectant ingredients in manufactured cigarettes to control and maintain…”
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Oncogenicity Evaluations of Chemopreventive Soy Components in p53(+/–) (p53 knockout) Mice by Johnson, William D., Dooley, Lawrence, Morrissey, Robert L., Arp, Lawrence, Kapetanovic, Izet, Crowell, James A., McCormick, David L.

“…Epidemiologic data suggest that soy consumption may protect against cancer induction in several tissues in humans. Although the soy components responsible for…”
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Preclinical toxicity studies of kahalalide F, a new anticancer agent: single and multiple dosing regimens in the rat by BROWN, Alan P, MORRISSEY, Robert L, FAIRCLOTH, Glynn T, LEVINE, Barry S

“…Kahalalide F (KF) is a new anticancer agent currently in clinical trials for solid tumors, including prostate cancer. During the preclinical development of…”
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Endocrine effects of dehydroepiandrosterone and its fluorinated analog, fluasterone, in rats by Brown, Alan P., Kirchner, Debra L., Morrissey, Robert L., Das, Saroj R., Fitzgerald, Robert L., Crowell, James A., Levine, Barry S.

“…Cancer chemoprevention is the use of pharmacologic agents to inhibit the development of cancer. The adrenal steroid dehydroepiandrosterone (DHEA) has…”
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Oral Toxicity of 1,2-Dithiole-3-Thione, a Potential Cancer Chemopreventive Agent, in the Rat by Brown, Alan P., Morrissey, Robert L., Tolhurst, Thomas A., Crowell, James A., Levine, Barry S.

“…This study examined the toxicity of 1,2-dithiole-3-thione (D3T) in rats following 14 days of daily oral (gavage) administration. D3T, an extensive inducer of…”
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Susceptible and resistant subgroups in genetically identical populations: response of mouse liver neoplasia and body weight to phenobarbital by Wolff, G L, Morrissey, R L, Chen, J J

“…Following 17-19 months of feeding 500 p.p.m. sodium phenobarbital (PB) in the diet to yellow Avy/A and agouti A/a (C3H X VY) F1 hybrid male mice, two subgroups…”
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Exposure to 60 Hz magnetic fields and risk of lymphoma in PIM transgenic and TSG-p53 (p53 knockout) mice by MCCORMICK, D. L, RYAN, B. M, FINDLAY, J. C, GAUGER, J. R, JOHNSON, T. R, MORRISSEY, R. L, BOORMAN, G. A

“…The results of a number of epidemiology studies suggest that exposure to power frequency (50 and 60 Hz) magnetic fields may be a risk factor for hematopoietic…”
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Difluoromethylornithine in combination with tamoxifen in female rats : 13-week oral toxicity study by BROWN, A. P, MORRISSEY, R. L, CROWELL, J. A, LEVINE, B. S

“…Cancer chemoprevention is the use of pharmacologic or natural agents to inhibit the development of cancer. Difluoromethylornithine (DFMO) is an irreversible…”
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Thirteen-week oral toxicity study of difluoromethylornithine in combination with tamoxifen citrate in female dogs by BROWN, A. P, MORRISSEY, R. L, CROWELL, J. A, LEVINE, B. S

“…Cancer chemoprevention is the use of pharmacologic or natural agents to inhibit the development of cancer. Difluoromethylornithine (DFMO) is an irreversible…”
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Subchronic Toxicity of Triethylenetetramine Dihydrochloride in B6C3F1 Mice and F344 Rats by GREENMAN, DAVID L., MORRISSEY, ROBERT L., BLAKEMORE, WILLIAM, CROWELL, JAMES, SIITONEN, PAUL, FELTON, PAUL, ALLEN, RICHARD, CRONIN, GERALD

“…Triethylenetetramine dihydrochloride (trien-2HCl; CAS No. 38260-01-04), a chelating agent used to treat Wilson's disease patients who are intolerant of the…”
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A 2-Year Comparison Study of Crl:CD BR and Hsd:Sprague-Dawley SD Rats by PETTERSEN, JOHN C., MORRISSEY, ROBERT L., SAUNDERS, DONALD R., PAVKOV, KENNETH L., LUEMPERT, LOUIS G., TURNIER, JOHN C., MATHESON, DALE W., SCHWARTZ, DANIEL R.

“…In this 2-year study, the suitability of the Hsd:Sprague-Dawley SD (SD) as a replacement for the Crl:CD BR (CD) rat was assessed by comparing survival rates,…”
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Tumorigenic responses to lindane in mice: potentiation by a dominant mutation by Wolff, G L, Roberts, D W, Morrissey, R L, Greenman, D L, Allen, R R, Campbell, W L, Bergman, H, Nesnow, S, Frith, C H

“…Obese mottled yellow Avy/a, lean pseudoagouti Avy/a and lean black a/a (YS X VY) F-1 hybrid female mice were fed diet containing 160 p.p.m. lindane…”
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Diabetogenic response to streptozotocin varies among obese yellow and among lean agouti (BALB/c x VY)F1 hybrid mice by Wolff, G L, Greenman, D L, Frigeri, L G, Morrissey, R L, Suber, R L, Felton, R P

“…To test the hypothesis that the elevated insulin levels in obese neoplasia-susceptible yellow Avy/- mice might be a major factor stimulating tumor formation,…”
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The mechanism of action of vitamin D in the intestine by Bikle, Daniel D, Morrissey, Robert L, Zolock, David T

“…The transport of calcium and phosphate from the gut's lumen to the blood stream is regulated by vitamin D acting through its metabolite 1,25 dihydroxy vitamin…”
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Action of vitamin D on intestinal calcium transport by Bikle, D D, Zolock, D T, Morrissey, R L

“…The means by which 1,25(OH)2D3 regulates calcium transport across the intestine still remains an enigma. The movement of calcium across the brush border…”
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Calcium-binding protein: its cellular localization in jejunum, kidney and pancreas by Morrissey, R L, Bucci, T J, Richard, B, Empson, N, Lufkin, E G

“…Calcium-binding protein (CaBP) was localized with peroxidase-labeled antibody in human jejunum and kidney, and in kidney and pacreas of several animal species…”
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