Search Results - "Morrissey, Michael"

General Methods for Evolutionary Quantitative Genetic Inference from Generalized Mixed Models by de Villemereuil, Pierre, Schielzeth, Holger, Nakagawa, Shinichi, Morrissey, Michael

“…Methods for inference and interpretation of evolutionary quantitative genetic parameters, and for prediction of the response to selection, are best developed…”
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SELECTION AND EVOLUTION OF CAUSALLY COVARYING TRAITS by Morrissey, Michael B.

“…When traits cause variation in fitness, the distribution of phenotype, weighted by fitness, necessarily changes. The degree to which traits cause fitness…”
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Evolutionary quantitative genetics of nonlinear developmental systems by Morrissey, Michael B.

“…In quantitative genetics, the effects of developmental relationships among traits on microevolution are generally represented by the contribution of pleiotropy…”
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Variation in reaction norms: Statistical considerations and biological interpretation by Morrissey, Michael B., Liefting, Maartje

“…Analysis of reaction norms, the functions by which the phenotype produced by a given genotype depends on the environment, is critical to studying many aspects…”
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UNIFICATION OF REGRESSION-BASED METHODS FOR THE ANALYSIS OF NATURAL SELECTION by Morrissey, Michael B., Sakrejda, Krzysztof

“…Regression analyses are central to characterization of the form and strength of natural selection in nature. Two common analyses that are currently used to…”
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The role of selection and evolution in changing parturition date in a red deer population by Bonnet, Timothée, Morrissey, Michael B, Morris, Alison, Morris, Sean, Clutton-Brock, Tim H, Pemberton, Josephine M, Kruuk, Loeske E B

“…Changing environmental conditions cause changes in the distributions of phenotypic traits in natural populations. However, determining the mechanisms…”
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DIRECTIONAL SELECTION IN TEMPORALLY REPLICATED STUDIES IS REMARKABLY CONSISTENT by Morrissey, Michael B., Hadfield, Jarrod D.

“…Temporal variation in selection is a fundamental determinant of evolutionary outcomes. A recent paper presented a synthetic analysis of temporal variation in…”
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The missing fraction problem as an episodes of selection problem by Mittell, Elizabeth A, Morrissey, Michael B

“…In evolutionary quantitative genetics, the missing fraction problem refers to a specific kind of bias in parameters estimated later in life that occurs when…”
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Use of Circulating Tumor DNA for Cancer Immunotherapy by Snyder, Alexandra, Morrissey, Michael P, Hellmann, Matthew D

“…Liquid biopsy offers a versatile, noninvasive opportunity to diagnose, characterize, and monitor disease in patients with cancer. There are particularly…”
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The Maintenance of Genetic Variation Due to Asymmetric Gene Flow in Dendritic Metapopulations by Morrissey, Michael B., de Kerckhove, Derrick T.

“…Dendritic landscapes can have ecological properties that differ importantly from simpler spatial arrangements of habitats. Most dendritic landscapes are…”
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Association of MTOR Mutations With Developmental Brain Disorders, Including Megalencephaly, Focal Cortical Dysplasia, and Pigmentary Mosaicism by Mirzaa, Ghayda M, Campbell, Catarina D, Solovieff, Nadia, Goold, Carleton, Jansen, Laura A, Menon, Suchithra, Timms, Andrew E, Conti, Valerio, Biag, Jonathan D, Adams, Carissa, Boyle, Evan August, Collins, Sarah, Ishak, Gisele, Poliachik, Sandra, Girisha, Katta M, Yeung, Kit San, Chung, Brian Hon Yin, Rahikkala, Elisa, Gunter, Sonya A, McDaniel, Sharon S, Macmurdo, Colleen Forsyth, Bernstein, Jonathan A, Martin, Beth, Leary, Rebecca, Mahan, Scott, Liu, Shanming, Weaver, Molly, Doerschner, Michael, Jhangiani, Shalini, Muzny, Donna M, Boerwinkle, Eric, Gibbs, Richard A, Lupski, James R, Shendure, Jay, Saneto, Russell P, Novotny, Edward J, Wilson, Christopher J, Sellers, William R, Morrissey, Michael, Hevner, Robert F, Ojemann, Jeffrey G, Guerrini, Renzo, Murphy, Leon O, Winckler, Wendy, Dobyns, William B

“…Focal cortical dysplasia (FCD), hemimegalencephaly, and megalencephaly constitute a spectrum of malformations of cortical development with shared…”
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Spectroscopy, manipulation and trapping of neutral atoms, molecules, and other particles using optical nanofibers: a review by Morrissey, Michael J, Deasy, Kieran, Frawley, Mary, Kumar, Ravi, Prel, Eugen, Russell, Laura, Truong, Viet Giang, Chormaic, Síle Nic

“…The use of tapered optical fibers, i.e., optical nanofibers, for spectroscopy and the detection of small numbers of particles, such as neutral atoms or…”
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A note on simulating null distributions for G matrix comparisons by Morrissey, Michael B., Hangartner, Sandra, Monro, Keyne

“…Genetic variances and covariances, summarized in G matrices, are key determinants of the course of adaptive evolution. Consequently, understanding how G…”
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Fluctuating optimum and temporally variable selection on breeding date in birds and mammals by de Villemereuil, Pierre, Charmantier, Anne, Arlt, Debora, Bize, Pierre, Brekke, Patricia, Brouwer, Lyanne, Cockburn, Andrew, Côté, Steeve D., Dobson, F. Stephen, Evans, Simon R., Festa-Bianchet, Marco, Gamelon, Marlène, Hamel, Sandra, Hegelbach, Johann, Jerstad, Kurt, Kempenaers, Bart, Kruuk, Loeske E. B., Kumpula, Jouko, Kvalnes, Thomas, McAdam, Andrew G., McFarlane, S. Eryn, Morrissey, Michael B., Pärt, Tomas, Pemberton, Josephine M., Qvarnström, Anna, Røstad, Ole Wiggo, Schroeder, Julia, Senar, Juan Carlos, Sheldon, Ben C., van de Pol, Martijn, Visser, Marcel E., Wheelwrighta, Nathaniel T., Tuftob, Jarle, Chevin, Luis-Miguel

“…Temporal variation in natural selection is predicted to strongly impact the evolution and demography of natural populations, with consequences for the rate of…”
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Quantifying the causal pathways contributing to natural selection by Henshaw, Jonathan M., Morrissey, Michael B., Jones, Adam G.

“…The consequences of natural selection can be understood from a purely statistical perspective. In contrast, an explicitly causal approach is required to…”
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Analytical results for directional and quadratic selection gradients for log‐linear models of fitness functions by Morrissey, Michael B., Goudie, I. B. J.

“…Log‐linear models are widely used for assessing determinants of fitness in empirical studies, for example, in determining how reproductive output depends on…”
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Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia by Orlando, Elena J., Han, Xia, Tribouley, Catherine, Wood, Patricia A., Leary, Rebecca J., Riester, Markus, Levine, John E., Qayed, Muna, Grupp, Stephan A., Boyer, Michael, De Moerloose, Barbara, Nemecek, Eneida R., Bittencourt, Henrique, Hiramatsu, Hidefumi, Buechner, Jochen, Davies, Stella M., Verneris, Michael R., Nguyen, Kevin, Brogdon, Jennifer L., Bitter, Hans, Morrissey, Michael, Pierog, Piotr, Pantano, Serafino, Engelman, Jeffrey A., Winckler, Wendy

“…We identified genetic mutations in CD19 and loss of heterozygosity at the time of CD19 – relapse to chimeric antigen receptor (CAR) therapy. The mutations are…”
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Analogues of the fundamental and secondary theorems of selection, assuming a log-normal distribution of expected fitness by Morrissey, Michael B, Bonnet, Timothée

“…It is increasingly common for studies of evolution in natural populations to infer the quantitative genetic basis of fitness (e.g., the additive genetic…”
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ecologist's guide to the animal model by Wilson, Alastair J., Réale, Denis, Clements, Michelle N., Morrissey, Michael M., Postma, Erik, Walling, Craig A., Kruuk, Loeske E. B., Nussey, Daniel H.

“…1. Efforts to understand the links between evolutionary and ecological dynamics hinge on our ability to measure and understand how genes influence phenotypes,…”
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spatial patterns of directional phenotypic selection by Siepielski, Adam M, Gotanda, Kiyoko M, Morrissey, Michael B, Diamond, Sarah E, DiBattista, Joseph D, Carlson, Stephanie M, Thrall, Peter

“…Local adaptation, adaptive population divergence and speciation are often expected to result from populations evolving in response to spatial variation in…”
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