Search Results - "Morrissey, Mark"
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The role of engram cells in the systems consolidation of memory
Published in Nature reviews. Neuroscience (01-08-2018)“…What happens to memories as days, weeks and years go by has long been a fundamental question in neuroscience and psychology. For decades, researchers have…”
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Engrams and circuits crucial for systems consolidation of a memory
Published in Science (American Association for the Advancement of Science) (07-04-2017)“…Episodic memories initially require rapid synaptic plasticity within the hippocampus for their formation and are gradually consolidated in neocortical networks…”
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Prefrontal Neural Ensembles Develop Selective Code for Stimulus Associations within Minutes of Novel Experiences
Published in The Journal of neuroscience (21-10-2020)“…Prevailing theories posit that the hippocampus rapidly learns stimulus conjunctions during novel experiences, whereas the neocortex learns slowly through…”
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Distributed representations of temporal stimulus associations across regular-firing and fast-spiking neurons in rat medial prefrontal cortex
Published in Journal of neurophysiology (01-01-2020)“…The prefrontal cortex has been implicated in various cognitive processes, including working memory, executive control, decision making, and relational…”
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Parvalbumin and GAD65 interneuron inhibition in the ventral hippocampus induces distinct behavioral deficits relevant to schizophrenia
Published in The Journal of neuroscience (05-11-2014)“…Hyperactivity within the ventral hippocampus (vHPC) has been linked to both psychosis in humans and behavioral deficits in animal models of schizophrenia. A…”
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Diversity of mnemonic function within the entorhinal cortex: A meta-analysis of rodent behavioral studies
Published in Neurobiology of learning and memory (01-11-2014)“…•Entorhinal cortex (EC) is an essential component of the hippocampal memory system.•EC consists of six anatomically-defined sub-regions.•Spatial and…”
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Confidence and barriers: Analysis of factors associated with timely routine childhood vaccination in Canada during the COVID-19 pandemic
Published in Vaccine (24-10-2024)“…Routine childhood vaccination is a crucial component of public health in Canada and worldwide. To facilitate catch-up from the global decline in routine…”
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Unilateral lateral entorhinal inactivation impairs memory expression in trace eyeblink conditioning
Published in PloS one (19-12-2013)“…Memory in trace eyeblink conditioning is mediated by an inter-connected network that involves the hippocampus (HPC), several neocortical regions, and the…”
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Generalizable knowledge outweighs incidental details in prefrontal ensemble code over time
Published in eLife (14-02-2017)“…Memories for recent experiences are rich in incidental detail, but with time the brain is thought to extract latent rules and structures common across past…”
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Entorhinal tau pathology disrupts hippocampal-prefrontal oscillatory coupling during associative learning
Published in Neurobiology of aging (01-10-2017)“…A neural signature of asymptomatic preclinical Alzheimer's disease (AD) is disrupted connectivity between brain regions; however, its underlying mechanisms…”
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Functional dissociation within the entorhinal cortex for memory retrieval of an association between temporally discontiguous stimuli
Published in The Journal of neuroscience (18-04-2012)“…Anatomical connectivity and single neuron coding suggest a segregation of information representation within lateral (LEC) and medial (MEC) portions of the…”
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Phasic and tonic neuron ensemble codes for stimulus-environment conjunctions in the lateral entorhinal cortex
Published in eLife (06-07-2017)“…The lateral entorhinal cortex (LEC) is thought to bind sensory events with the environment where they took place. To compare the relative influence of…”
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13
Neonatal detection of Aicardi Goutières Syndrome by increased C26:0 lysophosphatidylcholine and interferon signature on newborn screening blood spots
Published in Molecular genetics and metabolism (01-11-2017)“…Aicardi Goutières Syndrome (AGS) is a heritable interferonopathy associated with systemic autoinflammation causing interferon (IFN) elevation, central nervous…”
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Liquid chromatography-tandem mass spectrometry analysis of 17-hydroxyprogesterone in dried blood spots revealed matrix effect on immunoassay
Published in Analytical and bioanalytical chemistry (01-01-2019)“…Immunoassays for measuring 17-hydroxyprogesterone (17-OHP) produce high rates of false positives that impact the identification of congenital adrenal…”
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Enduring deficits in contextual and auditory fear conditioning after adolescent, not adult, social instability stress in male rats
Published in Neurobiology of learning and memory (2011)“…► Adolescent social stress impaired retrieval of context and cue conditioning. ► Deficits in performance after adolescent stress regardless of time since…”
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Comparison of C26:0-carnitine and C26:0-lysophosphatidylcholine as diagnostic markers in dried blood spots from newborns and patients with adrenoleukodystrophy
Published in Molecular genetics and metabolism (01-12-2017)“…X-linked adrenoleukodystrophy (ALD) is the most common leukodystrophy with a birth incidence of 1:14,700 live births. The disease is caused by mutations in…”
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Increased Entorhinal-Prefrontal Theta Synchronization Parallels Decreased Entorhinal-Hippocampal Theta Synchronization during Learning and Consolidation of Associative Memory
Published in Frontiers in behavioral neuroscience (2012)“…Memories are thought to be encoded as a distributed representation in the neocortex. The medial prefrontal cortex (mPFC) has been shown to support the…”
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Global Precipitation at One-Degree Daily Resolution from Multisatellite Observations
Published in Journal of hydrometeorology (01-02-2001)“…The One-Degree Daily (1DD) technique is described for producing globally complete daily estimates of precipitation on a 1° × 1° lat/long grid from currently…”
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Estimating Aggression from Emotionally Neutral Faces: Which Facial Cues are Diagnostic?
Published in Perception (London) (01-01-2010)“…The facial width-to-height ratio, a size-independent sexually dimorphic property of the human face, is correlated with aggressive behaviour in men…”
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Cholinergic, but not NMDA, receptors in the lateral entorhinal cortex mediate acquisition in trace eyeblink conditioning
Published in Hippocampus (01-11-2015)“…ABSTRACT Anatomical and electrophysiological studies collectively suggest that the entorhinal cortex consists of several subregions, each of which is involved…”
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