Search Results - "Morrison, Ron F"

Impact of reference gene selection for target gene normalization on experimental outcome using real-time qRT-PCR in adipocytes by Ferguson, Bradley S, Nam, Heesun, Hopkins, Robin G, Morrison, Ron F

“…With the current rise in obesity-related morbidities, real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR) has become a widely used…”
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Sex Steroid Hormones Regulate Leptin Transcript Accumulation and Protein Secretion in 3T3-L1 Cells by Jenks, Mónica Z., Fairfield, Heather E., Johnson, Erik C., Morrison, Ron F., Muday, Gloria K.

“…Leptin is an adipokine produced by fat cells that regulates food consumption and metabolic activity. Sexual dimorphism in leptin and fat stores have been…”
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DUSP5 functions as a feedback regulator of TNFα-induced ERK1/2 dephosphorylation and inflammatory gene expression in adipocytes by Habibian, Justine S., Jefic, Mitra, Bagchi, Rushita A., Lane, Robert H., McKnight, Robert A., McKinsey, Timothy A., Morrison, Ron F., Ferguson, Bradley S.

“…Adipose tissue inflammation is a central pathological element that regulates obesity-mediated insulin resistance and type II diabetes. Evidence demonstrates…”
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Modulation of IL‐27 in adipocytes during inflammatory stress by Nam, Heesun, Ferguson, Bradley S., Stephens, Jacqueline M., Morrison, Ron F.

“…Objective While it is well established that adipose tissue‐derived inflammation plays an important role in the pathogenic mechanisms linking obesity with…”
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Impact of obesity on IL-12 family gene expression in insulin responsive tissues by Nam, Heesun, Ferguson, Bradley S, Stephens, Jacqueline M, Morrison, Ron F

“…Mounting evidence has established a role for chronic inflammation in the development of obesity-induced insulin resistance, as genetic ablation of…”
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Curcumin Inhibits 3T3-L1 Preadipocyte Proliferation by Mechanisms Involving Post-transcriptional p27 Regulation by Ferguson, Bradley S, Nam, Heesun, Morrison, Ron F

“…Previous reports from our lab have shown that Skp2 is necessary for p27 degradation and cell cycle progression during adipocyte differentiation. Data presented…”
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Hormonal signaling and transcriptional control of adipocyte differentiation by Morrison, R F, Farmer, S R

“…Recent advances regarding the biology of adipose tissue have identified the adipocyte as an important mediator in many physiologic and pathologic processes…”
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Dual-specificity phosphatases regulate mitogen-activated protein kinase signaling in adipocytes in response to inflammatory stress by Ferguson, Bradley S., Nam, Heesun, Morrison, Ron F.

“…Obesity is a strong predictor of heart disease, insulin resistance, and type II diabetes. Chronic, low-grade inflammation links obesity and insulin resistance…”
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Evidence for Cytosolic p27(Kip1) Ubiquitylation and Degradation during Adipocyte Hyperplasia by Auld, Corinth A., Morrison, Ron F.

“…Objective: Subcellular localization has been shown to play an important role in determining activity and accumulation of p27 protein during cell cycle…”
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Phosphorylation of the JAK2-STAT5 Pathway in Response to Acute Aerobic Exercise by CONSITT, Leslie A, WIDEMAN, Laurie, HICKEY, Matthew S, MORRISON, Ron F

“…Growth hormone (GH) is a powerful stimulator of the Janus kinase 2 (JAK2)-signal transducer and activator of transcription 5 (STAT5) pathway. Acute exercise is…”
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Hormonal induction of adipogenesis induces Skp2 expression through PI3K and MAPK pathways by Auld, Corinth A., Caccia, Carla D., Morrison, Ron F.

“…We have previously shown that the F‐box protein, S‐phase kinase‐associated protein (Skp2) plays a mechanistic role in targeting the cell‐cycle inhibitor, p27…”
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Helenalin-mediated post-transcriptional regulation of p21(Cip1) inhibits 3T3-L1 preadipocyte proliferation by Fernandes, Karishma M., Auld, Corinth A., Hopkins, Robin G., Morrison, Ron F.

“…We have previously shown that post‐transcriptional mechanisms involving the 26S proteasome regulate the cyclin‐dependent kinase inhibitors (CKIs), p21(Cip1)…”
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Mitogen-Dependent Regulation of DUSP1 Governs ERK and p38 Signaling During Early 3T3-L1 Adipocyte Differentiation by Ferguson, Bradley S., Nam, Heesun, Stephens, Jacqueline M., Morrison, Ron F.

“…Knowledge concerning mechanisms that control proliferation and differentiation of preadipocytes is essential to our understanding of adipocyte hyperplasia and…”
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Oncostatin M Is Produced in Adipose Tissue and Is Regulated in Conditions of Obesity and Type 2 Diabetes by Sanchez-Infantes, David, White, Ursula A, Elks, Carrie M, Morrison, Ron F, Gimble, Jeffrey M, Considine, Robert V, Ferrante, Anthony W, Ravussin, Eric, Stephens, Jacqueline M

“…Context: Adipose tissue is a highly active endocrine organ that secretes many factors that affect other tissues and whole-body metabolism. Adipocytes are…”
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Peroxisome-proliferator-activated receptor gamma suppresses Wnt/beta-catenin signalling during adipogenesis by Moldes, Marthe, Zuo, Ying, Morrison, Ron F, Silva, David, Park, Bae-Hang, Liu, Jiajian, Farmer, Stephen R

“…The Wnt/beta-catenin signalling pathway appears to operate to maintain the undifferentiated state of preadipocytes by inhibiting adipogenic gene expression. To…”
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Conjugated linoleic acid induces human adipocyte delipidation: autocrine/paracrine regulation of MEK/ERK signaling by adipocytokines by Brown, J Mark, Boysen, Maria Sandberg, Chung, Soonkyu, Fabiyi, Olowatoyin, Morrison, Ron F, Mandrup, Susanne, McIntosh, Michael K

“…Dietary conjugated linoleic acid (CLA) reduces body fat in animals and some humans. Here we show that trans-10, cis-12 CLA, but not cis-9, trans-11 CLA, when…”
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Isomer-specific regulation of metabolism and PPARγ signaling by CLA in human preadipocytes by Brown, J.Mark, Boysen, Maria Sandberg, Jensen, Søren Skov, Morrison, Ron F., Storkson, Jayne, Lea-Currie, Renee, Pariza, Michael, Mandrup, Susanne, McIntosh, Michael K.

“…Trans -10, cis -12 conjugated linoleic acid (CLA) has previously been shown to be the CLA isomer responsible for CLA-induced reductions in body fat in animal…”
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Skp2-mediated p27(Kip1) degradation during S/G2 phase progression of adipocyte hyperplasia by Auld, Corinth A., Fernandes, Karishma M., Morrison, Ron F.

“…p27(Kip1), an important regulator of Cdk2 activity and G1/S transition, is tightly regulated in a cell‐type and condition‐specific manner to integrate…”
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Novel effect of helenalin on Akt signaling and Skp2 expression in 3T3-L1 preadipocytes by Auld, Corinth A., Hopkins, Robin G., Fernandes, Karishma M., Morrison, Ron F.

“…We have previously shown that the F-box protein, Skp2, is highly regulated during preadipocyte proliferation and plays a mechanistic role in p27 degradation…”
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The Expression and Regulation of STATs during 3T3-L1 Adipocyte Differentiation by Stephens, J M, Morrison, R F, Pilch, P F

“…STATs (Signal Transducers and Activators of Transcription) comprise a family of transcription factors that reside in the cytoplasm of resting cells. In…”
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