Search Results - "Morrison, Janna L"
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SHEEP MODELS OF INTRAUTERINE GROWTH RESTRICTION: FETAL ADAPTATIONS AND CONSEQUENCES
Published in Clinical and experimental pharmacology & physiology (01-07-2008)“…SUMMARY 1 Intrauterine growth restriction (IUGR) has been associated with poor perinatal health outcomes. Animal models have been used to investigate why IUGR…”
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Let's Talk about Placental Sex, Baby: Understanding Mechanisms That Drive Female- and Male-Specific Fetal Growth and Developmental Outcomes
Published in International journal of molecular sciences (15-06-2021)“…It is well understood that sex differences exist between females and males even before they are born. These sex-dependent differences may contribute to altered…”
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Nutrition in Pregnancy: Optimising Maternal Diet and Fetal Adaptations to Altered Nutrient Supply
Published in Nutrients (04-06-2016)“…n/a…”
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Placental adaptations in growth restriction
Published in Nutrients (08-01-2015)“…The placenta is the primary interface between the fetus and mother and plays an important role in maintaining fetal development and growth by facilitating the…”
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Fetal growth restriction, catch-up growth and the early origins of insulin resistance and visceral obesity
Published in Pediatric nephrology (Berlin, West) (01-04-2010)“…There is an association between growing slowly before birth, accelerated growth in early postnatal life and the emergence of insulin resistance, visceral…”
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Placenta-Specific Transcripts Containing Androgen Response Elements Are Altered In Silico by Male Growth Outcomes
Published in International journal of molecular sciences (01-02-2024)“…A birthweight centile (BWC) below the 25th is associated with an elevated risk of adverse perinatal outcomes, particularly among males. This male vulnerability…”
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Maternal tadalafil treatment does not increase uterine artery blood flow or oxygen delivery in the pregnant ewe
Published in Experimental physiology (01-06-2024)“…Increasing placental perfusion (PP) could improve outcomes of growth‐restricted fetuses. One way of increasing PP may be by using phosphodiesterase (PDE)‐5…”
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Fetal hemodynamics and cardiac streaming assessed by 4D flow cardiovascular magnetic resonance in fetal sheep
Published in Journal of cardiovascular magnetic resonance (21-01-2019)“…To date it has not been possible to obtain a comprehensive 3D assessment of fetal hemodynamics because of the technical challenges inherent in imaging small…”
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Methamphetamine administration increases hepatic CYP1A2 but not CYP3A activity in female guinea pigs
Published in PloS one (12-05-2020)“…Methamphetamine use has increased over the past decade and the first use of methamphetamine is most often when women are of reproductive age. Methamphetamine…”
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Preclinical models of maternal asthma and progeny outcomes: a scoping review
Published in European respiratory review (31-01-2024)“…There is an increased risk of adverse perinatal outcomes in the ∼17% of women with asthma during pregnancy. The mechanisms linking maternal asthma and adverse…”
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Feasibility of detecting myocardial infarction in the sheep fetus using late gadolinium enhancement CMR imaging
Published in Journal of cardiovascular magnetic resonance (13-09-2017)“…Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging has enabled the accurate assessment of myocardial infarction (MI). However,…”
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Betamethasone improved near‐term neonatal lamb lung maturation in experimental maternal asthma
Published in Experimental physiology (01-11-2024)“…Maternal asthma is associated with increased rates of neonatal lung disease, and fetuses from asthmatic ewes have fewer surfactant‐producing cells and lower…”
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Adverse Intrauterine Environment and Cardiac miRNA Expression
Published in International journal of molecular sciences (06-12-2017)“…Placental insufficiency, high altitude pregnancies, maternal obesity/diabetes, maternal undernutrition and stress can result in a poor setting for growth of…”
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Advanced magnetic resonance imaging in human placenta: insights into fetal growth restriction and congenital heart disease
Published in Frontiers in cardiovascular medicine (23-07-2024)“…Placental function plays a crucial role in fetal development, as it serves as the primary interface for delivery of nutrients and oxygen from the mother to…”
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Intrauterine Growth Restriction and Differential Patterns of Hepatic Growth and Expression of IGF1, PCK2, and HSDL1 mRNA in the Sheep Fetus in Late Gestation
Published in Biology of reproduction (01-06-2009)“…Fetal adaptations to periods of substrate deprivation can result in the programming of glucose intolerance, insulin resistance, and metabolic dysfunction in…”
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Normalisation of surfactant protein -A and -B expression in the lungs of low birth weight lambs by 21 days old
Published in PloS one (26-09-2017)“…Intrauterine growth restriction (IUGR) induced by placental restriction (PR) in the sheep negatively impacts lung and pulmonary surfactant development during…”
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Impact of the Addition of a Centrifugal Pump in a Preterm Miniature Pig Model of the Artificial Placenta
Published in Frontiers in physiology (22-07-2022)“…The recent demonstration of normal development of preterm sheep in an artificial extrauterine environment has renewed interest in artificial placenta (AP)…”
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Maternal Nutrient Restriction Alters Ca2+ Handling Properties and Contractile Function of Isolated Left Ventricle Bundles in Male But Not Female Juvenile Rats
Published in PloS one (25-09-2015)“…Intrauterine growth restriction (IUGR), defined as a birth weight below the 10th centile, may be caused by maternal undernutrition, with evidence that IUGR…”
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Maternal sleep during pregnancy and poor fetal outcomes: A scoping review of the literature with meta-analysis
Published in Sleep medicine reviews (01-10-2018)“…There is a wealth of evidence to say that sleep impacts maternal health during pregnancy, however, little has been published on fetal health and maternal…”
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Impact of embryo number and maternal undernutrition around the time of conception on insulin signaling and gluconeogenic factors and microRNAs in the liver of fetal sheep
Published in American journal of physiology: endocrinology and metabolism (01-05-2014)“…This study aimed to determine whether exposure of the oocyte and/or embryo to maternal undernutrition results in the later programming of insulin action in the…”
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