Search Results - "Morrison, Emma E"

Vasopressin Regulates Extracellular Vesicle Uptake by Kidney Collecting Duct Cells by Oosthuyzen, Wilna, Scullion, Kathleen M, Ivy, Jessica R, Morrison, Emma E, Hunter, Robert W, Starkey Lewis, Philip J, O'Duibhir, Eoghan, Street, Jonathan M, Caporali, Andrea, Gregory, Christopher D, Forbes, Stuart J, Webb, David J, Bailey, Matthew A, Dear, James W

“…Extracellular vesicles (ECVs) facilitate intercellular communication along the nephron, with the potential to change the function of the recipient cell…”
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Safety and Efficacy of the SNAP 12-hour Acetylcysteine Regimen for the Treatment of Paracetamol Overdose by Pettie, Janice M, Caparrotta, Thomas M, Hunter, Robert W, Morrison, Emma E, Wood, David M, Dargan, Paul I, Thanacoody, Ruben H, Thomas, Simon H L, Elamin, Muhammad E M O, Francis, Ben, Webb, David J, Sandilands, Euan A, Eddleston, Michael, Dear, James W

“…Acetylcysteine (NAC) is effective at preventing liver injury after paracetamol overdose. The Scottish and Newcastle Anti-emetic Pre-treatment for Paracetamol…”
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Transfer of hepatocellular microRNA regulates cytochrome P450 2E1 in renal tubular cells by Matthews, Olivia, Morrison, Emma E., Tranter, John D., Starkey Lewis, Philip, Toor, Iqbal S., Srivastava, Abhishek, Sargeant, Rebecca, Rollison, Helen, Matchett, Kylie P., Kendall, Timothy J., Gray, Gillian A., Goldring, Chris, Park, Kevin, Denby, Laura, Dhaun, Neeraj, Bailey, Matthew A., Henderson, Neil C., Williams, Dominic, Dear, James W.

“…Extracellular microRNAs enter kidney cells and modify gene expression. We used a Dicer-hepatocyte-specific microRNA conditional-knock-out (Dicer-CKO) mouse to…”
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Direct Detection of miR-122 in Hepatotoxicity Using Dynamic Chemical Labeling Overcomes Stability and isomiR Challenges by López-Longarela, Barbara, Morrison, Emma E, Tranter, John D, Chahman-Vos, Lianne, Léonard, Jean-François, Gautier, Jean-Charles, Laurent, Sébastien, Lartigau, Aude, Boitier, Eric, Sautier, Lucile, Carmona-Saez, Pedro, Martorell-Marugan, Jordi, Mellanby, Richard J, Pernagallo, Salvatore, Ilyine, Hugh, Rissin, David M, Duffy, David C, Dear, James W, Díaz-Mochón, Juan J

“…Circulating microRNAs are biomarkers reported to be stable and translational across species. MicroRNA-122 (miR-122) is a hepatocyte-specific microRNA biomarker…”
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Acetylcysteine has No Mechanistic Effect in Patients at Risk of Contrast‐Induced Nephropathy: A Failure of Academic Clinical Science by Sandilands, Euan A., Rees, Jessica M. B., Raja, Khuram, Dhaun, Neeraj, Morrison, Emma E., Hickson, Kirsty, Wraight, Jonathan, Gray, Tanya, Briody, Lesley, Cameron, Sharon, Thompson, Adrian P., Johnston, Neil R., Uren, Neal, Goddard, Jane, Treweeke, Andy, Rushworth, Gordon, Webb, David J., Bateman, D. Nicholas, Norrie, John, Megson, Ian L., Eddleston, Michael

“…Contrast‐induced nephropathy (CIN) is a major complication of imaging in patients with chronic kidney disease (CKD). The publication of an academic randomized…”
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Principles of management of the poisoned patient by Morrison, Emma E, Sandilands, Euan A

“…It would be challenging for all doctors to have a detailed knowledge of every poison they may meet in their career and so it is important to become proficient…”
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Principal results of a randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with a 12 h regimen of N-acetylcysteine for paracetamol overdose (POP trial) by Morrison, Emma E., Oatey, Katherine, Gallagher, Bernadette, Grahamslaw, Julia, O'Brien, Rachel, Black, Polly, Oosthuyzen, Wilna, Lee, Robert J., Weir, Christopher J., Henriksen, Dennis, Dear, James W.

“…The POP Trial was a phase 1, open-label, rising-dose, randomised study that explored the safety and tolerability of calmangafodipir (superoxide dismutase…”
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First-in-Man Demonstration of Direct Endothelin-Mediated Natriuresis and Diuresis by Hunter, Robert W, Moorhouse, Rebecca, Farrah, Tariq E, MacIntyre, Iain M, Asai, Takae, Gallacher, Peter J, Kerr, Debbie, Melville, Vanessa, Czopek, Alicja, Morrison, Emma E, Ivy, Jess R, Dear, James W, Bailey, Matthew A, Goddard, Jane, Webb, David J, Dhaun, Neeraj

“…Endothelin (ET) receptor antagonists are potentially novel therapeutic agents in chronic kidney disease and resistant hypertension, but their use is…”
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Randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with the 12-h regimen of N-acetylcysteine for paracetamol overdose-the PP100-01 for Overdose of Paracetamol (POP) trial: study protocol for a randomised controlled trial by Dear, James

“…Paracetamol (acetaminophen) overdose (POD) is the commonest cause of acute liver failure in Europe and North America. Current treatment involves the use of the…”
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Adverse reactions to intravenous acetylcysteine in paracetamol poisoning by Sandilands, Euan A., Morrison, Emma E., Bateman, D. Nicholas

“…Intravenous acetylcysteine is used for the management of paracetamol overdose worldwide. Recently, there has been increasing recognition of its adverse…”
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UK supply of chlortalidone for hypertension must be restored by Morrison, Emma E, Turtle, Emma J, Webb, David J

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Principles of management of the poisoned patient by Morrison, Emma E., Sandilands, Euan A.

“…One of the fundamental complications within toxicology is that patients may not know or disclose what they have been poisoned with. Consequently, a sound and…”
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Principal results of a randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with a 12 h regimen of N-acetylcysteine for paracetamol overdose (POP trial)Research in context by Emma E. Morrison, Katherine Oatey, Bernadette Gallagher, Julia Grahamslaw, Rachel O'Brien, Polly Black, Wilna Oosthuyzen, Robert J. Lee, Christopher J. Weir, Dennis Henriksen, James W. Dear

“…Background: The POP Trial was a phase 1, open-label, rising-dose, randomised study that explored the safety and tolerability of calmangafodipir (superoxide…”
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UK supply must be restored by Morrison, Emma E, Turtle, Emma J, Webb, David J

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