Search Results - "Morrison, Donald"
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novel double‐tryptophan peptide pheromone controls competence in Streptococcus spp. via an Rgg regulator
Published in Molecular microbiology (01-11-2010)“…All streptococcal genomes encode the alternative sigma factor SigX and 21 SigX‐dependent proteins required for genetic transformation, yet no pyogenic…”
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Identification and Characterization of Negative Regulators of Rgg1518 Quorum Sensing in Streptococcus pneumoniae
Published in Journal of bacteriology (25-07-2023)“…Streptococcus pneumoniae is an agent of otitis media, septicemia, and meningitis and remains the leading cause of community-acquired pneumonia regardless of…”
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Exit from competence for genetic transformation in Streptococcus pneumoniae is regulated at multiple levels
Published in PloS one (22-05-2013)“…Development of natural competence in S. pneumoniae entails coordinated expression of two sets of genes. Early gene expression depends on ComE, a response…”
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Control of competence for DNA transformation in streptococcus suis by genetically transferable pherotypes
Published in PloS one (26-06-2014)“…Here we show that S. suis, a major bacterial pathogen of pigs and emerging pathogen in humans responds to a peptide pheromone by developing competence for DNA…”
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Evolution via recombination: Cell-to-cell contact facilitates larger recombination events in Streptococcus pneumoniae
Published in PLoS genetics (13-06-2018)“…Homologous recombination in the genetic transformation model organism Streptococcus pneumoniae is thought to be important in the adaptation and evolution of…”
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Competence in Streptococcus pneumoniae and Close Commensal Relatives: Mechanisms and Implications
Published in Frontiers in cellular and infection microbiology (03-04-2019)“…The mitis group of streptococci comprises species that are common colonizers of the naso-oral-pharyngeal tract of humans. and are close relatives and share…”
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Pheromone Recognition and Selectivity by ComR Proteins among Streptococcus Species
Published in PLoS pathogens (01-12-2016)“…Natural transformation, or competence, is an ability inherent to bacteria for the uptake of extracellular DNA. This process is central to bacterial evolution…”
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Competence for Genetic Transformation in Streptococcus pneumoniae: Mutations in σA Bypass the ComW Requirement for Late Gene Expression
Published in Journal of bacteriology (01-09-2016)“…Streptococcus pneumoniae is able to integrate exogenous DNA into its genome by natural genetic transformation. Transient accumulation of high levels of the…”
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Competence pili in Streptococcus pneumoniae are highly dynamic structures that retract to promote DNA uptake
Published in Molecular microbiology (01-08-2021)“…The competence pili of transformable Gram‐positive species are phylogenetically related to the diverse and widespread class of extracellular filamentous…”
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Competence beyond Genes: Filling in the Details of the Pneumococcal Competence Transcriptome by a Systems Approach
Published in Journal of bacteriology (01-07-2019)“…DNA uptake by natural competence is a central process underlying the genetic plasticity, biology, and virulence of the human respiratory opportunistic pathogen…”
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Competence for Genetic Transformation in Streptococcus pneumoniae: Mutations in σA Bypass the comW Requirement
Published in Journal of bacteriology (01-11-2014)“…Competence for genetic transformation in the genus Streptococcus depends on an alternative sigma factor, σX, for coordinated synthesis of 23 proteins, which…”
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Development of Competence for Genetic Transformation of Streptococcus mutans in a Chemically Defined Medium
Published in Journal of Bacteriology (01-08-2012)“…Streptococcus mutans develops competence for genetic transformation in response to regulatory circuits that sense at least two peptide pheromones. One peptide,…”
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The pneumococcal σX activator, ComW, is a DNA-binding protein critical for natural transformation
Published in The Journal of biological chemistry (19-07-2019)“…Natural genetic transformation via horizontal gene transfer enables rapid adaptation to dynamic environments and contributes to both antibiotic resistance and…”
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Competence for Natural Genetic Transformation in the Streptococcus bovis Group Streptococci S. infantarius and S. macedonicus
Published in Journal of Bacteriology (01-06-2013)“…Natural genetic transformation is common among many species of the genus Streptococcus, but it has never, or rarely, been reported for the Streptococcus…”
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Femtoliter droplet confinement of Streptococcus pneumoniae: bacterial genetic transformation by cell-cell interaction in droplets
Published in Lab on a chip (12-02-2019)“…Streptococcus pneumoniae (pneumococcus), a deadly bacterial human pathogen, uses genetic transformation to gain antibiotic resistance. Genetic transformation…”
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Cryptic Competence Pathway in Streptococcus pyogenes Is Controlled by a Peptide Pheromone
Published in Journal of Bacteriology (01-09-2012)“…Horizontal gene transfer is an important means of bacterial evolution that is facilitated by transduction, conjugation, and natural genetic transformation…”
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Markerless Genome Editing in Competent Streptococci
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Selective markers employed in classical mutagenesis methods using natural genetic transformation can affect gene expression, risk phenotypic effects, and…”
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HtrA‐mediated selective degradation of DNA uptake apparatus accelerates termination of pneumococcal transformation
Published in Molecular microbiology (01-10-2019)“…Summary Natural transformation mediates horizontal gene transfer, and thereby promotes exchange of antibiotic resistance and virulence traits among bacteria…”
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Journal of Marketing Research: 1964–1969, the Bob Ferber Years
Published in Journal of marketing research (01-02-2014)Get full text
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Markerless Genome Editing in Competent Streptococci
Published in Methods in molecular biology (Clifton, N.J.) (2017)“…Selective markers employed in classical mutagenesis methods using natural genetic transformation can affect gene expression, risk phenotypic effects, and…”
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