Search Results - "Morrison, Alastair D"
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Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes
Published in Proceedings of the National Academy of Sciences - PNAS (12-07-2011)“…The generation of reactive oxygen species (ROS) is inherent to immune responses. ROS are crucially involved in host defense against pathogens by promoting…”
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The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain
Published in Pain (Amsterdam) (30-09-2008)“…It has been postulated that the G protein-coupled receptor, GPR55, is a third cannabinoid receptor. Given that the ligands at the CB 1 and CB 2 receptors are…”
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Dysregulation of Specialized Delay/Interference-Dependent Working Memory Following Loss of Dysbindin-1A in Schizophrenia-Related Phenotypes
Published in Neuropsychopharmacology (New York, N.Y.) (01-05-2017)“…Dysbindin-1, a protein that regulates aspects of early and late brain development, has been implicated in the pathobiology of schizophrenia. As the functional…”
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UDP-glucose modulates gastric function through P2Y14 receptor-dependent and -independent mechanisms
Published in American journal of physiology: Gastrointestinal and liver physiology (01-04-2009)“…P2Y receptors have been reported to modulate gastrointestinal functions. The newest family member is the nucleotide-sugar receptor P2Y14. P2ry14 mRNA was…”
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Development of glucose intolerance in male transgenic mice overexpressing human glycogen synthase kinase-3β on a muscle-specific promoter
Published in Metabolism, clinical and experimental (01-10-2004)“…Glycogen synthase kinase-3 (GSK-3) protein levels and activity are elevated in skeletal muscle in type 2 diabetes, and inversely correlated with both glycogen…”
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Adenoviral-mediated Cre expression effectively suppresses GlyT1 binding in the thalamic area of GlyT1 conditional knock-out mice
Published in Journal of neuroscience methods (30-11-2010)“…▶ We investigated the use of adenoviral vector-mediated Cre expression to mediate localized gene modulation in the specific thalamic area. ▶ This technology…”
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Nucleotide Receptor P2Y14 Modulates Hematopoietic Stem Cell Response to Tissue Injury Altering Stem Cell Preservation and Tissue Recovery
Published in Blood (16-11-2006)“…P2 receptors are functionally diverse cell surface receptors that bind nucleotides adenine (ADP, ATP) and uridine (UDP, UTP). P2Y receptors are metabotropic G…”
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Development of glucose intolerance in male transgenic mice overexpressing human glycogen synthase kinase-3beta on a muscle-specific promoter
Published in Metabolism, clinical and experimental (01-10-2004)“…Glycogen synthase kinase-3 (GSK-3) protein levels and activity are elevated in skeletal muscle in type 2 diabetes, and inversely correlated with both glycogen…”
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Journal Article