Search Results - "Morrish, Tammy A."
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Multiple Fates of L1 Retrotransposition Intermediates in Cultured Human Cells
Published in Molecular and Cellular Biology (01-09-2005)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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2
Short telomeres initiate telomere recombination in primary and tumor cells
Published in PLoS genetics (01-01-2009)“…Human tumors that lack telomerase maintain telomeres by alternative lengthening mechanisms. Tumors can also form in telomerase-deficient mice; however, the…”
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3
Similarities between long interspersed element-1 (LINE-1) reverse transcriptase and telomerase
Published in Proceedings of the National Academy of Sciences - PNAS (20-12-2011)“…Long interspersed element-1 (LINE-1 or L1) retrotransposons encode two proteins (ORF1p and ORF2p) that contain activities required for conventional…”
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4
Editorial: Mobile Genetic Elements in Cellular Differentiation, Genome Stability, and Cancer
Published in Frontiers in chemistry (04-12-2017)Get full text
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5
Analysis of 5' junctions of human LINE-1 and Alu retrotransposons suggests an alternative model for 5'-end attachment requiring microhomology-mediated end-joining
Published in Genome research (01-06-2005)“…Insertion of the human non-LTR retrotransposon LINE-1 (L1) into chromosomal DNA is thought to be initiated by a mechanism called target-primed reverse…”
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6
A Comprehensive Analysis of Recently Integrated Human Ta L1 Elements
Published in American journal of human genetics (01-08-2002)“…The Ta ( transcribed, subset a) subfamily of L1 LINEs ( long interspersed elements) is characterized by a 3-bp ACA sequence in the 3′ untranslated region and…”
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7
Endonuclease-independent LINE-1 retrotransposition at mammalian telomeres
Published in Nature (08-03-2007)“…Long interspersed element-1 (LINE-1 or L1) elements are abundant, non-long-terminal-repeat (non-LTR) retrotransposons that comprise ∼17% of human DNA. The…”
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8
DNA repair mediated by endonuclease-independent LINE-1 retrotransposition
Published in Nature genetics (01-06-2002)“…Long interspersed elements (LINE-1s) are abundant retrotransposons in mammalian genomes that probably retrotranspose by target site-primed reverse…”
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Molecular Cloning and Characterization of DEFCAP-L and -S, Two Isoforms of a Novel Member of the Mammalian Ced-4 Family of Apoptosis Proteins
Published in The Journal of biological chemistry (23-03-2001)“…We report the deduced amino acid sequences of two alternately spliced isoforms, designated DEFCAP-L and -S, that differ in 44 amino acids and encode a novel…”
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10
Of man in mice
Published in Nature genetics (01-12-2002)“…L1 retrotransposition is ongoing, and has dramatically affected the evolution and structure of mammalian genomes. Despite their impact on the genome, little is…”
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11
Short Telomeres Initiate Telomere Recombination in Primary and Tumor Cells: e1000357
Published in PLoS genetics (01-01-2009)“…Human tumors that lack telomerase maintain telomeres by alternative lengthening mechanisms. Tumors can also form in telomerase-deficient mice; however, the…”
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12
The role of recombination genes during telomere maintenance in telomerase deficient tumors and primary cells
Published in The FASEB journal (01-04-2011)“…Cells with unlimited growth potential such as tumors and stem cells require telomere maintenance mechanisms. Some human tumors lack telomerase and instead…”
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13
Negative Regulation of Selected bHLH Proteins by eHAND
Published in Experimental cell research (15-06-2000)“…The bHLH protein eHAND plays an important role in the development of extraembryonic, mesodermal, and cardiac cell lineages, presumably through…”
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14
Endonuclease-independent LINE-1 retrotransposition
Published 2005“…Transposable element derived sequences comprise −40% of the human genome. Long Interspersed Elements (L1s or LINEs) comprise ∼17% of the genome and mobilize…”
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Dissertation