Search Results - "Morrish, P K"
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Frontal, midbrain and striatal dopaminergic function in early and advanced Parkinson's disease A 3D [18F]dopa-PET study
Published in Brain (London, England : 1878) (01-09-1999)“…We have studied focal changes in dopaminergic function throughout the brain volume in early and advanced Parkinson's disease by applying statistical parametric…”
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Measuring the rate of progression and estimating the preclinical period of Parkinson’s disease with [18F]dopa PET
Published in Journal of neurology, neurosurgery and psychiatry (01-03-1998)“…OBJECTIVES To measure the rate of progression in striatal [18F]dopa metabolism in a large group (n=32) of patients with Parkinson’s disease, to estimate the…”
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An [18F]dopa–PET and clinical study of the rate of progression in Parkinson’s disease
Published in Brain (London, England : 1878) (01-04-1996)“…We have studied disease progression in a group of 10 patients with recent onset idiopathic Parkinson's disease [mean age 53.7±12.6 years, mean duration…”
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Clinical and [18F] dopa PET findings in early Parkinson's disease
Published in Journal of neurology, neurosurgery and psychiatry (01-12-1995)“…Twenty seven patients with recent onset (mean symptom duration 22 (SD 14) months, Hoehn and Yahr score 1.8 (SD 0.7)) Parkinson's disease were studied with…”
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Regional changes in [18F]dopa metabolism in the striatum in Parkinson's disease
Published in Brain (London, England : 1878) (01-12-1996)“…We have investigated regional changes in dopamine metabolism within the basal ganglia with clinical progression of idiopathic Parkinson's disease, using…”
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REAL and CALM: What have we learned?
Published in Movement disorders (01-07-2003)Get full text
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Parkinson's disease is not a long-latency illness
Published in Movement disorders (01-11-1997)Get full text
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The harsh realities facing the use of SPECT imaging in monitoring disease progression in Parkinson’s disease
Published in Journal of neurology, neurosurgery and psychiatry (01-10-2003)“…[...]the UPDRS scores were influenced by dopaminergic drug effects and therefore were not suitable to study correlations with [123I][beta]-CIT SPECT measures…”
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The danger of ignoring a migraine
Published in Postgraduate medical journal (01-01-2002)“…Fundoscopy revealed the presence of arteriolar-venous nipping, "flame shaped" and "dot and blot" retinal haemorrhages, "cotton wool" spots, and papilloedema…”
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Graves' disease presenting as hemiparkinsonism
Published in Journal of endocrinological investigation (01-03-2001)Get full text
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The effect of entacapone (OR-611) on brain [18F]-6-L-fluorodopa metabolism: implications for levodopa therapy of Parkinson's disease
Published in Neurology (01-07-1994)“…We used PET and [18F]-6-L-fluorodopa ([18F]dopa) to measure the effect of a peripheral COMT inhibitor, entacapone, on the extracerebral metabolism and…”
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Leukoencephalopathy associated with khat misuse
Published in Journal of neurology, neurosurgery and psychiatry (01-10-1999)“…The leaves are also chewed by members of the Yemeni and Somali community in the United Kingdom. 1 The psychoactive constituents of khat are cathin…”
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Dopaminergic function in familial Parkinson's disease: a clinical and 18F-dopa positron emission tomography study
Published in Annals of neurology (01-02-1997)“…There is increasing evidence for familial aggregation in Parkinson's disease (PD). It is possible that some asymptomatic relatives of PD patients have…”
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The rate of progression of Parkinson's disease. A longitudinal [18F]DOPA PET study
Published in Advances in neurology (1996)Get more information
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Inadequate neurology services undermine patient care in the UK
Published in BMJ (Online) (18-06-2015)“…Action is required to restore balance and ensure fair access…”
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A comparison of the progression of early Parkinson's disease in patients started on ropinirole or L-dopa: an 18F-dopa PET study
Published in Journal of neural transmission (01-12-2002)“…To study the relative rates of progression of early Parkinson's disease (PD) in patients started on a dopamine agonist, ropinirole, or L-dopa. A double-blind…”
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Preclinical diagnosis of Parkinson's disease
Published in Advances in neurology (1999)Get more information
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Statistical parametric mapping with 18F-dopa PET shows bilaterally reduced striatal and nigral dopaminergic function in early Parkinson’s disease
Published in Journal of neurology, neurosurgery and psychiatry (01-06-1999)“…OBJECTIVE To apply statistical parametric mapping to 18F-dopa PET data sets, to examine the regional distribution of changes in dopaminergic metabolism in…”
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Stroke and neurological illness: the real lottery
Published in BMJ (26-01-2010)Get full text
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