Search Results - "Morris, Lynsie M."

Loss of cone cyclic nucleotide-gated channel leads to alterations in light response modulating system and cellular stress response pathways: a gene expression profiling study by Ma, Hongwei, Thapa, Arjun, Morris, Lynsie M, Michalakis, Stylianos, Biel, Martin, Frank, Mark Barton, Bebak, Melissa, Ding, Xi-Qin

“…The cone photoreceptor cyclic nucleotide-gated (CNG) channel is essential for central and color vision and visual acuity. Mutations in the channel subunits…”
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Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapy by Carvalho, Livia S., Xu, Jianhua, Pearson, Rachael A., Smith, Alexander J., Bainbridge, James W., Morris, Lynsie M., Fliesler, Steven J., Ding, Xi-Qin, Ali, Robin R.

“…Mutations in the CNGB3 gene account for >50% of all known cases of achromatopsia. Although of early onset, its stationary character and the potential for rapid…”
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CNGA3 deficiency affects cone synaptic terminal structure and function and leads to secondary rod dysfunction and degeneration by Xu, Jianhua, Morris, Lynsie M, Michalakis, Stylianos, Biel, Martin, Fliesler, Steven J, Sherry, David M, Ding, Xi-Qin

“…To investigate rod function and survival after cone dysfunction and degeneration in a mouse model of cone cyclic nucleotide-gated (CNG) channel deficiency. Rod…”
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Notch1‐Mediated Tumor Suppression in Cervical Cancer with the Involvement of SST Signaling and Its Application in Enhanced SSTR‐Targeted Therapeutics by Franko‐Tobin, Laura G., Mackey, L. Vienna, Huang, Wei, Song, Xiangwei, Jin, Baofeng, Luo, Jing, Morris, Lynsie M., Liu, Minqiu, Fuselier, Joseph A., Coy, David H., Wu, Lizi, Sun, Lichun

“…The role of Notch signaling in cervical cancer is seemingly controversial. To confirm the function of Notch signaling in this type of cancer, we established a…”
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Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapy by CARVALHO, Livia S, JIANHUA XU, PEARSON, Rachael A, SMITH, Alexander J, BAINBRIDGE, James W, MORRIS, Lynsie M, FLIESLER, Steven J, DING, Xi-Qin, ALI, Robin R

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Investigation of cancer cell lines for peptide receptor-targeted drug development by Sun, Lichun, Luo, Jing, Mackey, L. Vienna, Morris, Lynsie M., Franko-Tobin, Laura G., LePage, Keith T., Coy, David H.

“…Many tumors highly express specific populations of G-protein-coupled receptors (GPCRs) that could be utilized for receptor-targeted therapy. We confirmed…”
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Application of human pancreatic carcinoid BON cells for receptor-targeted drug development by Sun, Lichun, Morris, Lynsie M., Luo, Jing, Mackey, L. Vienna, Leslie, Juliana S., Franko-Tobin, Laura G., Fuselier, Joseph A., LePage, Keith T., Coy, David H.

“…In our previous study, we found that several tumor cell lines displayed high receptor-specific binding affinity, one of which, the human pancreatic carcinoid…”
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