Search Results - "Morris, Josephine"
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Live imaging of collagen deposition during skin development and repair in a collagen I – GFP fusion transgenic zebrafish line
Published in Developmental biology (01-09-2018)“…Fibrillar collagen is a major component of many tissues but has been difficult to image in vivo using transgenic approaches because of problems associated with…”
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Proteolytic and Opportunistic Breaching of the Basement Membrane Zone by Immune Cells during Tumor Initiation
Published in Cell reports (Cambridge) (04-06-2019)“…Cancer-related inflammation impacts significantly on cancer development and progression. From early stages, neutrophils and macrophages are drawn to…”
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Journal Article -
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LARP1 haploinsufficiency is associated with an autosomal dominant neurodevelopmental disorder
Published in HGG advances (10-10-2024)“…Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) that affects approximately 4% of males and 1% of females in the United States. While…”
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Aryl Azide Photochemistry in Defined Protein Environments
Published in Organic letters (15-02-2013)“…A genetically encoded precursor to an aryl nitrene, para-azidophenylalanine, was introduced site specifically into proteins to deduce if distinct environments…”
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Advances in the mechanism and understanding of site-selective noncanonical amino acid incorporation
Published in Current opinion in structural biology (01-08-2011)“…► Important topics in NAA biological chemistry are: chemical functionality, fidelity, and efficiency. ► Tyrosyl and pyrrolysyl enzymes are amendable to an…”
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Regulation of β-Lactamase Activity by Remote Binding of Heme: Functional Coupling of Unrelated Proteins through Domain Insertion
Published in Biochemistry (Easton) (10-08-2010)“…Coupling the activities of normally disparate proteins into one functional unit has significant potential in terms of constructing novel switching components…”
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The Novel Nucleoside Analogue ProTide NUC-7738 Overcomes Cancer Resistance Mechanisms In Vitro and in a First-In-Human Phase I Clinical Trial
Published in Clinical cancer research (01-12-2021)“…Nucleoside analogues form the backbone of many therapeutic regimens in oncology and require the presence of intracellular enzymes for their activation. A…”
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Abstract 931: From bench to bedside: Using ProTide chemistry to transform 3'-deoxyadenosine into the novel anti-cancer agent Nuc-7738
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Abstract Background: 3'-deoxyadenosine (3'-dA; also known as cordycepin) is a nucleoside analog that has shown potent anti-cancer activity in non-clinical…”
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LARP1 isoform expression in human cancer cell lines
Published in RNA biology (01-02-2021)“…LARP1 is an oncogenic RNA-binding protein required for ribosome biogenesis and cancer cell survival. From published in vitro studies, there is disparity over…”
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Utilisation of amber suppression/non-natural amino acid technology for protein engineering and cellular control
Published 01-01-2013“…The amber suppression technology is an intracellular methodology that allows position specific incorporation of a specific non-natural amino acid (NAA) into…”
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Dissertation -
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Initiation of Rabbit Hemoglobin Synthesis: Methionine and Formylmethionine at the N-Terminal
Published in Proceedings of the National Academy of Sciences - PNAS (01-11-1970)“…Ribosome-bound peptides were prepared from rabbit reticulocytes incubated in a reaction mixture that contained all essential amino acids except tryptophan. The…”
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Protein Synthesis in the Maturing Reticulocyte
Published in The Journal of biological chemistry (10-04-1967)“…In order to determine why protein synthesis declines with reticulocyte maturation, rabbit reticulocytes separated by age on a density gradient of bovine serum…”
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READING ROOMS AND LIBRARIES FOR THE BLIND
Published in Library Journal (01-05-1909)Get full text
Magazine Article -
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Regulation of E2F by phosphorylation
Published 01-01-2000“…The E2F proteins are a family of transcription factors that function in regulating the G1 to S phase transition. The activity of E2F is regulated in a…”
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Dissertation -
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Patterns of spontaneous LH release in normo- and hyperprolactinaemic women
Published in Acta endocrinologica (Copenhagen) (01-07-1981)“…Hyperprolactinaemia may be associated with functional amenorrhoea. In order to evaluate the possible role of abnormal spontaneous LH secretion in…”
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Endogenous estrogen modulates phenothiazine stimulated prolactin secretion
Published in The journal of clinical endocrinology and metabolism (01-10-1976)“…The role of endogenous estrogen in the regulation of serum prolactin concentration in man is controversial. To evaluate the possible effect of endogenous…”
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Enhanced polyribosome recovery from reticulocytes using heparin
Published in Experimental cell research (01-02-1967)Get more information
Journal Article -
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Evelyn Waugh: The novel and its relation to other media
Published 01-01-1987“…Waugh's novels participate in the tendency within the novel tradition to borrow, parody, and criticize techniques from other media as part of the process of…”
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Dissertation