Search Results - "Morris, Andrew"
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GWAMA: software for genome-wide association meta-analysis
Published in BMC bioinformatics (28-05-2010)“…Despite the recent success of genome-wide association studies in identifying novel loci contributing effects to complex human traits, such as type 2 diabetes…”
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Long-term field comparison of multiple low-cost particulate matter sensors in an outdoor urban environment
Published in Scientific reports (16-05-2019)“…Exposure to ambient particulate matter (PM) air pollution is a leading risk factor for morbidity and mortality, associated with up to 8.9 million deaths/year…”
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3
Transethnic meta-analysis of genomewide association studies
Published in Genetic epidemiology (01-12-2011)“…The detection of loci contributing effects to complex human traits, and their subsequent fine‐mapping for the location of causal variants, remains a…”
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4
Metformin in Cancer Treatment and Prevention
Published in Annual review of medicine (14-01-2015)“…Patients with diabetes mellitus are at increased risk of cancer development. Metformin is a well-established, effective agent for the management of type 2…”
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Chimeric Antigen Receptor T Cells, the Shock of the New
Published in Critical care medicine (01-01-2022)Get full text
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6
Progress in defining the genetic contribution to type 2 diabetes susceptibility
Published in Current opinion in genetics & development (01-06-2018)“…Candidate gene, genome-wide association, exome array and sequencing studies have identified more than 140 loci associated with type 2 diabetes (T2D)…”
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Recessive Mutations in TRMT10C Cause Defects in Mitochondrial RNA Processing and Multiple Respiratory Chain Deficiencies
Published in American journal of human genetics (05-05-2016)“…Mitochondrial disorders are clinically and genetically diverse, with mutations in mitochondrial or nuclear genes able to cause defects in mitochondrial gene…”
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Antimicrobial-associated harm in critical care: a narrative review
Published in Intensive care medicine (01-02-2020)“…The belief that, for the individual patient, the benefit of prompt and continued use of antimicrobials outweighs any potential harm is a significant barrier to…”
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An evaluation of statistical approaches to rare variant analysis in genetic association studies
Published in Genetic epidemiology (01-02-2010)“…Genome‐wide association (GWA) studies have proved to be extremely successful in identifying novel common polymorphisms contributing effects to the genetic…”
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Structure Prediction of Li–Sn and Li–Sb Intermetallics for Lithium-Ion Batteries Anodes
Published in Chemistry of materials (25-07-2017)“…A variety of new stable and metastable Li–Sn and Li–Sb intermetallics are presented using the ab initio random structure searching (AIRSS) and species swapping…”
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Does This Adult Patient With Suspected Bacteremia Require Blood Cultures?
Published in JAMA : the journal of the American Medical Association (01-08-2012)“…CONTEXT Clinicians order blood cultures liberally among patients in whom bacteremia is suspected, though a small proportion of blood cultures yield…”
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GM-CSF targeting in COVID-19: an approach based on fragile foundations
Published in The European respiratory journal (01-02-2023)Get full text
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Ab Initio Study of Phosphorus Anodes for Lithium- and Sodium-Ion Batteries
Published in Chemistry of materials (12-04-2016)“…Phosphorus has received recent attention in the context of high-capacity and high-rate anodes for lithium- and sodium-ion batteries. Here, we present a…”
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Comprehensive Molecular Testing for Respiratory Pathogens in Community-Acquired Pneumonia
Published in Clinical infectious diseases (01-04-2016)“…Background. The frequent lack of a microbiological diagnosis in community-acquired pneumonia (CAP) impairs pathogen-directed antimicrobial therapy. This study…”
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Dioxin-like PCB 126 increases intestinal inflammation and disrupts gut microbiota and metabolic homeostasis
Published in Environmental pollution (1987) (01-11-2018)“…The gut microbiome is sensitive to diet and environmental exposures and is involved in the regulation of host metabolism. Additionally, gut inflammation is an…”
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Linking microbial communities to ecosystem functions: what we can learn from genotype-phenotype mapping in organisms
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (11-05-2020)“…Microbial physiological processes are intimately involved in nutrient cycling. However, it remains unclear to what extent microbial diversity or community…”
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Structural Evolution of Electrochemically Lithiated MoS2 Nanosheets and the Role of Carbon Additive in Li-Ion Batteries
Published in Chemistry of materials (25-10-2016)“…Understanding the structure and phase changes associated with conversion-type materials is key to optimizing their electrochemical performance in Li-ion…”
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Health data poverty: an assailable barrier to equitable digital health care
Published in The Lancet. Digital health (01-04-2021)“…Data-driven digital health technologies have the power to transform health care. If these tools could be sustainably delivered at scale, they might have the…”
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Methods for multiancestry genome-wide association study meta-analysis
Published in Annals of human genetics (18-07-2024)“…Genome-wide association studies (GWAS) have significantly enhanced our understanding of the genetic basis of complex diseases. Despite the technological…”
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Compartmentalisation of immune responses in critical illness: does it matter?
Published in Intensive care medicine (01-11-2022)Get full text
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