Search Results - "Morrell, M.J"

Resolution of central sleep apnoea following implantation of a left ventricular assist device by Vazir, A, Hastings, P.C, Morrell, M.J, Pepper, J, Henein, M.Y, Westaby, S, Poole-Wilson, P.A, Cowie, M.R, Simonds, A.K

“…Abstract Central sleep apnoea (CSA) occurs in up to 40% of patients with chronic heart failure (CHF). It is thought to be a consequence of CHF and is…”
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Use of levetiracetam in a population of patients aged 65 years and older: a subset analysis of the KEEPER trial by Ferrendelli, J.A., French, J., Leppik, I., Morrell, M.J., Herbeuval, A., Han, J., Magnus, L.

“…Levetiracetam (Keppra) was evaluated in a subset of patients aged ⩾65 years ( n=78) enrolled in a large ( n=1030) open-label, phase IV trial (the KEEPER…”
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Ageing does not influence the sleep-related decrease in the hypercapnic ventilatory response by Browne, H.A.K, Adams, L, Simonds, A.K, Morrell, M.J

“…In young people, a sleep-related reduction in the gain of the ventilatory chemoreflex feedback loop occurs; in the elderly, it has been reported that no…”
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Effect of surfactant on pharyngeal mechanics in sleeping humans: implications for sleep apnoea by Morrell, M.J, Arabi, Y, Zahn, B.R, Meyer, K.C, Skatrud, J.B, Safwan Badr, M

“…Instillation of surfactant into the pharyngeal lumen reduces the pressure required to reopen an occluded airway, and decreases the apnoea/hypopnoea index…”
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Obstructive sleep apnoea and Alzheimer’s disease: In search of shared pathomechanisms by Polsek, D., Gildeh, N., Cash, D., Winsky-Sommerer, R., Williams, S.C.R., Turkheimer, F., Leschziner, G.D., Morrell, M.J., Rosenzweig, I.

“…•Alzheimer’s disease (AD) is a significant public health concern.•The processes involved in the pathogenesis of AD are shown to overlap with those found in…”
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Efficacy of gabapentin as adjunctive therapy in a large, multicenter study by Morrell, M.J., McLean, M.J., Willmore, L.J., Privitera, M.D., Faught, R.E., Holmes, G.L., Magnus, L., Bernstein, P., Rose-Legatt, A., STEPS Study Group

“…The objective of this study was to determine the efficacy of gabapentin as adjunctive therapy in doses required to achieve the most effective seizure control…”
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Bone health in young women with epilepsy after one year of antiepileptic drug monotherapy by PACK, A. M, MORRELL, M. J, RANDALL, A, MCMAHON, D. J, SHANE, E

“…Antiepileptic drugs (AEDs) may have adverse effects on bone mineral density (BMD) and metabolism. We previously reported biochemical evidence of increased bone…”
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The association between obstructive sleep apnea and Alzheimer's disease: a meta-analysis perspective by Khazaie, H., Emamian, F., Tahmasian, M., Leschziner, G.D., Morrell, M.J., Hsiung, G.-Y.R., Rosenzweig, I., Sepehry, A.A.

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Effects of sleep deprivation on cognitive and physical performance in university students by Patrick, Y., Lee, A., Raha, O., Pillai, K., Gupta, S., Sethi, S., Mukeshimana, F., Gerard, L., Moghal, M.U., Saleh, S.N., Smith, S.F., Morrell, M.J., Moss, J.

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A high prevalence of sleep disordered breathing in men with mild symptomatic chronic heart failure due to left ventricular systolic dysfunction by Vazir, A., Hastings, P.C., Dayer, M., McIntyre, H.F., Henein, M.Y., Poole-Wilson, P.A., Cowie, M.R., Morrell, M.J., Simonds, A.K.

“…Background: Sleep disordered breathing (SDB) is common in severe chronic heart failure (CHF) and is associated with increased morbidity and mortality. The…”
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Sleep apnoea in older people by Glasser, M., Bailey, N., McMillan, A., Goff, E., Morrell, M.J.

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The KEEPER™ trial: levetiracetam adjunctive treatment of partial-onset seizures in an open-label community-based study by Morrell, M.J, Leppik, I, French, J, Ferrendelli, J, Han, J, Magnus, L

“…Purpose: Three randomized, placebo-controlled trials have demonstrated the safety and efficacy of levetiracetam, a new antiepileptic medication, as add-on…”
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Effect of CO2 inhalation on central sleep apnea and arousals from sleep by Szollosi, I, Jones, M, Morrell, M J, Helfet, K, Coats, A J S, Simonds, A K

“…CO(2) inhalation reduces central sleep apnea (CSA) in patients with congestive heart failure (CHF) and idiopathic CSA. CO(2) is also a stimulus for cortical…”
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The interaction between respiratory and autonomic function during sleep-related changes in pharyngeal airway patency by O'Driscoll, D.M., Morrell, M.J.

“…Sleep-related changes in pharyngeal function result in an increased resistance to airflow and in some people complete pharyngeal occlusion. Clinically,…”
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Corrigendum to “The KEEPER™ trial: levetiracetam adjunctive treatment of partial-onset seizures in an open-label community-based study” [Epilepsy Res. 54 (2003) 153–162] by Morrell, M.J., Leppik, I., French, J., Ferrendelli, J., Han, J., Magnus, L.

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Sleep apnoea and daytime function in the elderly—what is the impact of arousal frequency? by Browne, H.A.K, Adams, L, Simonds, A.K, Morrell, M.J

“…Arousals from sleep result in hyperventilation and hypocapnia that can lead to sleep apnoea. We have investigated whether sleep apnoea in the elderly is…”
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Scientific highlights from the European Sleep Research Society Congress, 2008 by Goff, E.A., Jackson, M.L., Shaikh, Z.F., Atalla, A., Hill, C.M., Morrell, M.J.

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Pneumatically Powered Drilling of Carbon Fibre Composites Using Synthetic Biodegradable Lubricating Oil: An Experimental Study by Morrell, Corydon, Hampson, Paul

“…Carbon fibre composites are a key component of aircraft structures because of their enhanced material properties such as favourable strength to weight ratios…”
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Gray matter deficits in epilepsy with schizophrenia-like symptoms by Marsh, L., Mathalon, D.H., Morrell, M.J., Pfefferbaum, A.

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Qualitative block design performance in epilepsy patients by Zipf, E.M., Shear, P.K., Winegarden, B.J., Morrell, M.J.

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