Search Results - "Morré, Dorothy M"
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Molecular Cloning and Characterization of a Candidate Human Growth-Related and Time-Keeping Constitutive Cell Surface Hydroquinone (NADH) Oxidase
Published in Biochemistry (Easton) (30-12-2008)“…ENOX (ECTO-NOX) proteins are growth-related cell surface proteins that catalyze both hydroquinone or NADH oxidation and protein disulfide−thiol interchange and…”
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ENOX2-based early detection (ONCOblot) of asbestos-induced malignant mesothelioma 4-10 years in advance of clinical symptoms
Published in Clinical proteomics (22-01-2016)“…Malignant mesothelioma is an aggressive, almost uniformly fatal tumor, caused primarily by exposure to asbestos. In this study, serum presence of…”
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3
Indolyl-quinuclidinols inhibit ENOX activity and endothelial cell morphogenesis while enhancing radiation-mediated control of tumor vasculature
Published in The FASEB journal (01-09-2009)“…There is a need for novel strategies that target tumor vasculature, specifically those that synergize with cytotoxic therapy, in order to overcome resistance…”
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ENOX2 Target for the Anticancer Isoflavone ME-143
Published in Oncology research (01-01-2014)“…ME-143 (NV-143), a synthetic isoflavone under clinical evaluation for efficacy in the management of ovarian and other forms of human cancer, blocked the…”
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Molecular Cloning and Characterization of a Tumor-Associated, Growth-Related, and Time-Keeping Hydroquinone (NADH) Oxidase (tNOX) of the HeLa Cell Surface
Published in Biochemistry (Easton) (19-03-2002)“…NOX proteins are growth-related cell surface proteins that catalyze both hydroquinone or NADH oxidation and protein disulfide interchange and exhibit…”
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6
Botanicals for age-related diseases: from field to practice
Published in The American journal of clinical nutrition (01-02-2008)“…The Purdue-University of Alabama Botanicals Research Center for Age Related Disease joins novel technologies to study the bioavailability of bioactive…”
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Essential role of copper in the activity and regular periodicity of a recombinant, tumor-associated, cell surface, growth-related and time-keeping hydroquinone (NADH) oxidase with protein disulfide-thiol interchange activity (ENOX2)
Published in Journal of bioenergetics and biomembranes (01-10-2010)“…ECTO-NOX proteins are growth-related cell surface proteins that catalyze both hydroquinone or NADH oxidation and protein disulfide interchange and exhibit…”
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ECTO-NOX target for the anticancer isoflavene phenoxodiol
Published in Oncology research (01-01-2007)“…Phenoxodiol, a synthetic isoflavene with clinical efficacy in the management of ovarian and other forms of human cancer, blocked the activity of a…”
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Mouse embryonic fibroblast cells from transgenic mice overexpressing tNOX exhibit an altered growth and drug response phenotype
Published in Journal of cellular biochemistry (15-05-2007)“…Mouse embryonic fibroblast (MEF) cells prepared from transgenic mice overexpressing a cancer‐specific and growth‐related cell surface NADH oxidase with protein…”
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Preferential inhibition by (−)-epigallocatechin-3-gallate of the cell surface NADH oxidase and growth of transformed cells in culture
Published in Biochemical pharmacology (01-10-2000)“…A drug-responsive and cancer-specific NADH oxidase of the mammalian plasma membrane, constitutively activated in transformed cells, was inhibited…”
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Monoascorbate free radical-dependent oxidation-reduction reactions of liver Golgi apparatus membranes
Published in Journal of bioenergetics and biomembranes (01-04-2010)“…Golgi apparatus from rat liver contain an ascorbate free radical oxidoreducatse that oxidizes NADH at neutral pH with monodehydroascorbate as acceptor to…”
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NAD+/NADH and/or CoQ/CoQH2 ratios from plasma membrane electron transport may determine ceramide and sphingosine-1-phosphate levels accompanying G1 arrest and apoptosis
Published in BioFactors (Oxford) (2005)“…To elucidate possible biochemical links between growth arrest from antiproliferative chemotherapeutic agents and apoptosis, our work has focused on agents…”
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Oxidative Stress Reduced by a Green Tea Concentrate and Capsicum Combination: Synergistic Effects
Published in Journal of dietary supplements (01-12-2013)“…ABSTRACTReactive oxygen species that are produced by aerobic metabolism and signaling cascades have the potential to play important roles in maintaining…”
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Capsaicin Inhibits Preferentially the NADH Oxidase and Growth of Transformed Cells in Culture
Published in Proceedings of the National Academy of Sciences - PNAS (14-03-1995)“…A hormone- and growth factor-stimulated NADH oxidase of the mammalian plasma membrane, constitutively activated in transformed cells, was inhibited…”
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Phenoxodiol Treatment Alters the Subsequent Response of ENOX2 (tNOX) and Growth of HeLa Cells to Paclitaxel and Cisplatin
Published in Molecular biotechnology (01-05-2009)“…Phenoxodiol is an experimental anticancer drug under development as a chemosensitizer intended to reverse multidrug resistance mechanisms in ovarian and…”
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Cancer type-specific tNOX isoforms: A putative family of redox protein splice variants with cancer diagnostic and prognostic potential
Published in BioFactors (Oxford) (2008)“…A proteomics approach with detection on western blots using an S‐peptide tagged pan‐tNOX (ENOX2) recombinant (scFv) antibody followed by alkaline…”
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Biochemical Basis for the Biological Clock
Published in Biochemistry (Easton) (08-10-2002)“…NADH oxidases at the external surface of plant and animal cells (ECTO-NOX proteins) exhibit stable and recurring patterns of oscillations with potentially…”
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Medicinal benefits of green tea: Part I. Review of noncancer health benefits
Published in The journal of alternative and complementary medicine (New York, N.Y.) (01-06-2005)“…Tea, in the form of green or black tea, is one of the most widely consumed beverages in the world. Extracts of tea leaves also are sold as dietary supplements…”
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Synergistic Capsicum-tea mixtures with anticancer activity
Published in Journal of pharmacy and pharmacology (01-07-2003)“…ABSTRACT We have demonstrated a synergy between a decaffeinated green tea concentrate and a vanilloid‐containing Capsicum preparation obtained commercially. At…”
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Omega-3 but Not Omega-6 Unsaturated Fatty Acids Inhibit the Cancer-Specific ENOX2 of the HeLa Cell Surface with No Effect on the Constitutive ENOX1
Published in Journal of dietary supplements (01-05-2010)“…Epidemiological and laboratory studies suggest that dietary fatty acids (oleic acid (in olive oil), eicosapentaenoic (EPA) and docosahexaenoic acids (DHA) (in…”
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