Search Results - "Morphew, Russell M."

Genome Sequencing and Pan-Genome Analysis of 23 Corallococcus spp. Strains Reveal Unexpected Diversity, With Particular Plasticity of Predatory Gene Sets by Livingstone, Paul G, Morphew, Russell M, Whitworth, David E

“…is an abundant genus of predatory soil myxobacteria, containing two species, (for which a genome sequence is available) and . To investigate the genomic basis…”
Get full text

Myxobacteria Are Able to Prey Broadly upon Clinically-Relevant Pathogens, Exhibiting a Prey Range Which Cannot Be Explained by Phylogeny by Livingstone, Paul G, Morphew, Russell M, Whitworth, David E

“…Myxobacteria are natural predators of microorganisms and the subjects of concerted efforts to identify novel antimicrobial compounds. Myxobacterial predatory…”
Get full text

Extracellular Vesicles in Microbes, Pathogens, and Infectious Diseases by Chow, Franklin Wang-Ngai, Morphew, Russell M

“…Extracellular vesicles (EVs) are nanosized lipid bilayer particles that are produced by all kinds of organisms, including both pathogenic and non-pathogenic…”
Get full text

Genome Analysis, Metabolic Potential, and Predatory Capabilities of Herpetosiphon llansteffanense sp. nov by Livingstone, Paul G, Morphew, Russell M, Cookson, Alan R, Whitworth, David E

“…spp. are ubiquitous, chemoheterotrophic, filamentous gliding bacteria with the ability to prey on other microbes through a "wolf pack" mechanism. The genus…”
Get full text

The importance of extracellular vesicle purification for downstream analysis: A comparison of differential centrifugation and size exclusion chromatography for helminth pathogens by Davis, Chelsea N, Phillips, Helen, Tomes, John J, Swain, Martin T, Wilkinson, Toby J, Brophy, Peter M, Morphew, Russell M

“…Robust protocols for the isolation of extracellular vesicles (EVs) from the rest of their excretory-secretory products are necessary for downstream studies and…”
Get full text

A dominance of Mu class glutathione transferases within the equine tapeworm Anoplocephala perfoliata by Northcote, Holly M., Wititkornkul, Boontarikaan, Cutress, David J., Allen, Nathan D., Brophy, Peter M., Wonfor, Ruth E., Morphew, Russell M.

“…The most common equine tapeworm, Anoplocephala perfoliata, has often been neglected amongst molecular investigations and has been faced with limited treatment…”
Get full text

Discovery of long non-coding RNAs in the liver fluke, Fasciola hepatica by McVeigh, Paul, McCammick, Erin, Robb, Emily, Brophy, Peter, Morphew, Russell M, Marks, Nikki J, Maule, Aaron G

“…Long non-coding (lnc)RNAs are a class of eukaryotic RNA that do not code for protein and are linked with transcriptional regulation, amongst a myriad of other…”
Get full text

Pilot Evaluation of Two Fasciola hepatica Biomarkers for Supporting Triclabendazole (TCBZ) Efficacy Diagnostics by Collett, Clare F, Morphew, Russell M, Timson, David, Phillips, Helen C, Brophy, Peter M

“…, the causative agent of fasciolosis, is a global threat to public health, animal welfare, agricultural productivity, and food security. In the ongoing absence…”
Get full text

Using next-generation sequencing to determine diversity of horse intestinal worms: identifying the equine ‘nemabiome’ by MITCHELL, Catriona J., O’SULLIVAN, Catherine M., PINLOCHE, Eric, WILKINSON, Toby, MORPHEW, Russell M., MCEWAN, Neil R.

“…Next-generation sequencing of DNA from nematode eggs has been utilised to give the first account of the equine ‘nemabiome’. In all equine faecal samples…”
Get full text

Excretory-secretory products from the brown stomach worm, Teladorsagia circumcincta, exert antimicrobial activity in in vitro growth assays by Rooney, James, Williams, Timothy L, Northcote, Holly M, Frankl, Fiona E. Karet, Price, Daniel R. G, Nisbet, Alasdair J, Morphew, Russell M, Cantacessi, Cinzia

“…Abstract Background Over the past decade, evidence has emerged of the ability of gastrointestinal (GI) helminth parasites to alter the composition of the host…”
Get full text

Fasciola hepatica Tegumental Antigen Suppresses Dendritic Cell Maturation and Function by Hamilton, Clare M, Dowling, David J, Loscher, Christine E, Morphew, Russell M, Brophy, Peter M, O'Neill, Sandra M

“…Parasitic worms and molecules derived from them have powerful anti-inflammatory properties and are shown to have therapeutic effects on inflammatory diseases…”
Get full text

Smell of Infection: A Novel, Noninvasive Method for Detection of Fish Excretory-Secretory Proteins by Pawluk, Rebecca J, Stuart, Rebekah, Garcia de Leaniz, Carlos, Cable, Joanne, Morphew, Russell M, Brophy, Peter M, Consuegra, Sofia

“…Chemical signals are produced by aquatic organisms following predatory attacks or perturbations such as parasitic infection. Ectoparasites feeding on fish…”
Get full text

Modulation of Rumen Microbes Through Extracellular Vesicle Released by the Rumen Fluke Calicophoron daubneyi by Allen, Nathan R, Taylor-Mew, Aspen R, Wilkinson, Toby J, Huws, Sharon, Phillips, Helen, Morphew, Russell M, Brophy, Peter M

“…Parasite derived extracellular vesicles (EVs) have been proposed to play key roles in the establishment and maintenance of infection. is a newly emerging…”
Get full text

Exploring and Expanding the Fatty-Acid-Binding Protein Superfamily in Fasciola Species by Morphew, Russell M, Wilkinson, Toby J, Mackintosh, Neil, Jahndel, Veronika, Paterson, Steve, McVeigh, Paul, Abbas Abidi, Syed. M, Saifullah, Khalid, Raman, Muthusamy, Ravikumar, Gopalakrishnan, LaCourse, James, Maule, Aaron, Brophy, Peter M

“…The liver flukes Fasciola hepatica and F. gigantica infect livestock worldwide and threaten food security with climate change and problematic control measures…”
Get full text

The Sigma class glutathione transferase from the liver fluke Fasciola hepatica by LaCourse, E James, Perally, Samirah, Morphew, Russell M, Moxon, Joseph V, Prescott, Mark, Dowling, David J, O'Neill, Sandra M, Kipar, Anja, Hetzel, Udo, Hoey, Elizabeth, Zafra, Rafael, Buffoni, Leandro, Pérez Arévalo, José, Brophy, Peter M

“…Liver fluke infection of livestock causes economic losses of over US$ 3 billion worldwide per annum. The disease is increasing in livestock worldwide and is a…”
Get full text

Comparative Proteomics of Excretory-Secretory Proteins Released by the Liver Fluke Fasciola hepatica in Sheep Host Bile and during in Vitro Culture ex Host by Morphew, Russell M, Wright, Hazel A, LaCourse, E James, Woods, Debra J, Brophy, Peter M

“…Livestock infection by the parasitic fluke Fasciola hepatica causes major economic losses worldwide. The excretory-secretory (ES) products produced by F…”
Get full text

RNAi dynamics in Juvenile Fasciola spp. Liver flukes reveals the persistence of gene silencing in vitro by McVeigh, Paul, McCammick, Erin M, McCusker, Paul, Morphew, Russell M, Mousley, Angela, Abidi, Abbas, Saifullah, Khalid M, Muthusamy, Raman, Gopalakrishnan, Ravikumar, Spithill, Terry W, Dalton, John P, Brophy, Peter M, Marks, Nikki J, Maule, Aaron G

“…Fasciola spp. liver fluke cause pernicious disease in humans and animals. Whilst current control is unsustainable due to anthelmintic resistance, gene…”
Get full text

Novel Equine Faecal Egg Diagnostics: Validation of the FECPAKG2 by Tyson, Fiona, Dalesman, Sarah, Brophy, Peter M., Morphew, Russell M.

“…Faecal egg counts (FECs) are the standard method of diagnosing the level of parasitic helminth egg shedding in horses and other grazing animals. Testing before…”
Get full text

Polyomic tools for an emerging livestock parasite, the rumen fluke Calicophoron daubneyi; identifying shifts in rumen functionality by Huson, Kathryn M, Morphew, Russell M, Allen, Nathan R, Hegarty, Matthew J, Worgan, Hillary J, Girdwood, Susan E, Jones, Eleanor L, Phillips, Helen C, Vickers, Martin, Swain, Martin, Smith, Daniel, Kingston-Smith, Alison H, Brophy, Peter M

“…Diseases caused by parasitic flatworms of rumen tissues (paramphistomosis) are a significant threat to global food security as a cause of morbidity and…”
Get full text

Evidence of Immune Modulators in the Secretome of the Equine Tapeworm Anoplocephala perfoliata by Wititkornkul, Boontarikaan, Hulme, Benjamin J., Tomes, John J., Allen, Nathan R., Davis, Chelsea N., Davey, Sarah D., Cookson, Alan R., Phillips, Helen C., Hegarty, Matthew J., Swain, Martin T., Brophy, Peter M., Wonfor, Ruth E., Morphew, Russell M.

“…Anoplocephala perfoliata is a neglected gastro-intestinal tapeworm, commonly infecting horses worldwide. Molecular investigation of A. perfoliata is hampered…”
Get full text