Search Results - "Morozkina, S. N."

Relaxation of Steric Strains of TTR-Type Amyloid Fibril Inhibitors Radically Changes the Results of Their Virtual Screening by Rumyantseva, V. K., Morozkina, S. N., Uspenskaya, M. V., Petukhov, M. G.

“…Using the results of virtual ligand screening (VLS) of a representative set of 66834 commercially available drug-like ligands and 8400 di- and tripeptides in…”
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Mangiferin-Loaded Nanofibers Based on Hyaluronic Acid by Klimshina, V. I., Snetkov, P. P., Morozkina, S. N., Uspenskaya, M. V.

“…A study is performed of the physical properties of aqueous organic spinning solutions based on hyaluronic acid with added mangiferin. Electrospinning is used…”
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Study of the Dynamics of Diflunisal Release from a Polymer Matrix by Mihajlova, P. A., Adamova, A. A., Generalova, Yu. E., Snetkov, P. P., Morozkina, S. N.

“…Introduction . The effectiveness of diflunisal in the treatment of cardiac amyloidosis has been clinically proven. Currently, only tablet forms of diflunisal…”
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Hyaluronic acid—curcumin electrospun fibers by Snetkov, P. P., Sitnikova, V. E., Uspenskaya, M. V., Morozkina, S. N., Olekhnovich, R. O.

“…Hyaluronic acid (HA)-curcumin electrospun fibers exhibiting antimicrobial, anti-inflammatory, and anti-tumorigenic activity were fabricated. It is shown that a…”
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Synthesis and Molecular Structure of D-Homo-B-nor-8α Analogs of Steroidal Estrogens by Shavva, A. G, Antimonova, O. I, Baigozin, D. V, Starova, G. L, Selivanov, S. I, Morozkina, S. N

“…According to the X-ray diffraction and NMR data, two D-homo-B-nor-8α-analogs of steroidal estrogens in crystal and in solution have similar conformations. The…”
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Synthesis and investigation of the biological properties of 6-oxa-8α-analogs of steroid estrogens containing a methyl group at C-4 by Morozkina, S. N, Selivanov, S. S, Selivanov, S. I, Drozdov, A. S, Eshchenko, N. D, Shavva, A. G

“…4-Methyl-substituted 6-oxa-8α-analogs of steroid estrogens have been synthesized and the ¹H and ¹³C NMR signals of these compounds have been completely…”
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Investigation of the conformational transformations in some 7α-methyl-6-oxa-14β-analogs of steroidal estrogens by NMR spectroscopy by Selivanov, S. I, Morozkina, S. N, Chentsova, A. S, Shavva, A. G

“…The stereochemical structure and conformational transformations of two 6-oxa-14β-estra-1,3,5(10), 8(9)-tetraenes having an α-methyl group at position 7 were…”
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Synthesis, structure, and biological properties of some 8α analogues of steroid estrogens with fluorine in position 2 by Belov, V. N., Dudkin, V. Yu, Urusova, E. A., Starova, G. L., Selivanov, S. I., Nikolaev, S. V., Eshchenko, N. D., Morozkina, S. N., Shavva, A. G.

“…A total synthesis of 8 alpha analogues of steroid estrogens with fluorine in position 2 was achieved. Structural features of these compounds were studied by…”
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Synthesis, structure, and biological properties of some 8alpha-analogues of steroid estrogens with fluorine in position 2 by Belov, V N, Dudkin, V Iu, Urusova, E A, Starova, G L, Selivanov, S I, Nikolaev, S V, Eshchenko, N D, Morozkina, S N, Shavva, A G

“…A total synthesis of 8alpha analogues of steroid estrogens with fluorine in position 2 was achieved. Structural features of these compounds were studied by the…”
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Synthesis and biological properties of D-homo-6-oxa-8α-analogues of steroid estrogens by Shavva, A. G., Morozkina, S. N., Ishchenko, I. V., Eliseev, I. I., Selivanov, S. I., Abusalimov, Sh. N., Selivanov, S. S., Kameneva, I. Yu, Eshchenko, N. D.

“…Modifications of D-homo-6-oxa-8 alpha -analogues of steroid estrogens were found to lead to a complete loss of the uterotropic and hypertriglyceridemic…”
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“Acetylene Zipper” Reactions and Pd-Cu-Catalyzed Cross-coupling in the Synthesis of Vicinal 1,3-Alkadiynylarylamines and Aminopyridines by Balova, I. A., Morozkina, S. N., Sorokoumov, V. N., Vinogradova, O. V., Vasilevskii, S. F.

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New 2-fluoro 8α-analogs of steroidal estrogens by Morozkina, S. N., Fidarov, A. F., Selivanov, S. I., Shavva, A. G.

“…New 8α-analogs of steroidal estrogens containing a fluorine atom in the 2-position have been synthesized with the goal of obtaining modified derivatives with…”
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Preparation and spatial structure of methyl ether of 7β-methyl-D-homo-6-oxaestra-1,3,5(10),8(9)-tetraen-17a-one by Morozkina, S. N., Zashikhina, N. N., Selivanov, S. I., Shavva, A. G.

“…Procedure of preparation of 7β-methyl-D-homo-6-oxa-1,3,5(10),8,(9)-estratetraen-17a-one methyl ether has been developed; the product conformation in the…”
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Synthesis and biological activity of some 8α-analogs of steroidal estrogens by Morozkina, S. N., Abusalimov, Sh. N., Selivanov, S. I., Shavva, A. G.

“…8α-Analogs of steroidal estrogens containing a methyl group on C 1 or an oxo group on C 6 were synthesized with a view to obtain compounds exhibiting selective…”
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Synthesis and some biological properties of sulfamates derived from 8α-analogs of steroidal estrogens by Morozkina, S. N., Gluzdikov, I. A., Drozdov, A. S., Selivanov, S. I., Kovalev, R. A., Filatov, M. V., Shavva, A. G.

“…Sulfamates derived from estrogens of the 8α-series have been synthesized, and their effect on the growth of MCF-7 breast cancer cells has been studied. The…”
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Study of osteoprotective and hypolipidemic effects of estrogen 8α-analogues by Eschenko, N D, Putilina, F E, Galkina, O V, Vilkova, V A, Zacharova, L I, Fidarov, A F, Morozkina, S N, Shavva, A G

“…The aim of this work was to study the ability of some estrogen 8α-analogues, that have CH3-group in the C-3 position, exhibit osteoprotective and…”
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Synthesis and studies of structure and biological properties of D-homoanalogs of steroid estrogens by Morozkina, S. N., Fidarov, A. F., Mushtukov, A. S., Selivanov, S. I., Starova, G. L., Shawa, A. G.

“…In order to estimate the potential of steroid estrogens modification, three D-homoanalogs of estrogens have been prepared; their structures and biological…”
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Synthesis and molecular structure study of 3-methoxy-7α-methyl-6-oxa-9β,14β-estra-1,3,5(10)-trien-17-one in solution by Selivanov, S. I., Morozkina, S. N., Shavva, A. G.

“…It was established by NMR spectroscopy that the catalytic hydrogenation of 3-methoxy-7α-methyl-6-oxa-14β-estra-1,3,5(10),8-tetraen-17-one leads to the…”
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Molecular structure and biological properties of some 16,16-dimethyl-D-homo-B-nor-9β analogs of steroid estrogens by Morozkina, S. N., Starova, G. L., Selivanov, S. I., Shavva, A. G.

“…The interproton distances in the molecule of 17aβ-acetoxy-16,16-dimethyl-3-methoxy-D-homo-Bnor-9β-estra-1,3,5(10)-triene, determined from the X-ray diffraction…”
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Ionic hydrogenation of estra-1,3,5(10),8,14-pentaenes by Morozkina, S. N., Nikol’skaya, S. K., Chentsova, A. S., Drozdov, A. S., Starova, G. L., Selivanov, S. I., Shavva, A. G.

“…The direction of ionic hydrogenation of estra-1,3,5(10),8,14-pentaenes with triethylsilane in the presence of trifluoroacetic acid is determined by the nature…”
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