Search Results - "Moroz, V. V."

METTL3 Inhibitors for Epitranscriptomic Modulation of Cellular Processes by Moroz‐Omori, Elena V., Huang, Danzhi, Kumar Bedi, Rajiv, Cheriyamkunnel, Sherry J., Bochenkova, Elena, Dolbois, Aymeric, Rzeczkowski, Maciej D., Li, Yaozong, Wiedmer, Lars, Caflisch, Amedeo

“…The methylase METTL3 is the writer enzyme of the N6‐methyladenosine (m6A) modification of RNA. Using a structure‐based drug discovery approach, we identified a…”
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Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation by Lee, Joo-Hyung, Wang, Ruoyu, Xiong, Feng, Krakowiak, Joanna, Liao, Zian, Nguyen, Phuoc T., Moroz-Omori, Elena V., Shao, Jiaofang, Zhu, Xiaoyu, Bolt, Michael J., Wu, Haoyi, Singh, Pankaj K., Bi, Mingjun, Shi, Caleb J., Jamal, Naadir, Li, Guojie, Mistry, Ragini, Jung, Sung Yun, Tsai, Kuang-Lei, Ferreon, Josephine C., Stossi, Fabio, Caflisch, Amedeo, Liu, Zhijie, Mancini, Michael A., Li, Wenbo

“…The mechanistic understanding of nascent RNAs in transcriptional control remains limited. Here, by a high sensitivity method methylation-inscribed nascent…”
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JLigand: a graphical tool for the CCP4 template-restraint library by Lebedev, Andrey A., Young, Paul, Isupov, Michail N., Moroz, Olga V., Vagin, Alexey A., Murshudov, Garib N.

“…Biological macromolecules are polymers and therefore the restraints for macromolecular refinement can be subdivided into two sets: restraints that are applied…”
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Morphology, membrane nanostructure and stiffness for quality assessment of packed red blood cells by Kozlova, E., Chernysh, A., Moroz, V., Sergunova, V., Gudkova, O., Manchenko, E.

“…Transfusion of packed red blood cells (PRBC) to patients in critical states is often accompanied by post-transfusion complications. This may be related with…”
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A Worst-Case Analysis of Trap-Assisted Tunneling Leakage in DRAM Using a Machine Learning Approach by Lee, J., Asenov, P., Aldegunde, M., Amoroso, S. M., Brown, A. R., Moroz, V.

“…The variability in trap-assisted tunneling leakage that is enhanced by random discrete dopants (RDD) causes refresh failure in scaled 6F 2 dynamic…”
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Сurrent condition of pine plantations of Kyiv Polisya under the influence of environmental factors by Moroz, V. V., Nykytyuk, Yu. A.

“…The article describes the climate change in the study region for the period 1968-2020. It was specified that over the past fifty-nine years there has been an…”
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Impact of General Anesthesia and Antioxidants on Cognitive, Static and Locomotor Functions During Laparoscopic Cholecystectomy by Moroz, V. V., Dolgikh, V. T., Karpitskaya, S. A.

“…   Aim of the study:  to reduce cognitive impairment during laparoscopic cholecystectomy by perioperative administration of drugs with antihypoxic and…”
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Genome rearrangements and selection in multi-chromosome bacteria Burkholderia spp by Bochkareva, Olga O, Moroz, Elena V, Davydov, Iakov I, Gelfand, Mikhail S

“…The genus Burkholderia consists of species that occupy remarkably diverse ecological niches. Its best known members are important pathogens, B. mallei and B…”
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FREQUENCY FEATURES OF THE NUMERICAL METHOD SAMPLING OF DIGITAL CONTROL SYSTEMS by Moroz, V. I., Vakarchuk, A. B.

“…Context. The studies of the frequency properties of the explicit multistep numerical integrators which use for sampling of continuous transfer function in the…”
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Coronavirus SARS-CoV-2: Hypotheses of Impact on the Circulatory System, Prospects for the Use of Perfluorocarbon Emulsion, and Feasibility of Biophysical Research Methods by Moroz, V. V., Chernysh, A. M., Kozlova, Elena K.

“…This paper highlights published hypotheses on the possibility of coronavirus SARS-CoV-2 entry into the bloodstream, its interaction with vascular endothelium,…”
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Prognostic Markers of Acute Suppurative Lung Disease by Fetlam, D. L., Chumachenko, A. G., Vyazmina, M. D., Moroz, V. V., Kuzovlev, A. N., Pisarev, V. M.

“…The mortality rate among patients with acute suppurative lung diseases (ASLD) in the ICU reaches 30%. Early, pathogenetically relevant biomarkers are needed to…”
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Sepsis-Associated Metabolites and Their Biotransformation by Intestinal Microbiota by Chernevskaya, E. A., Getsina, M. L., Cherpakov, R. A., Sorokina, E. A., Shabanov, A. K., Moroz, V. V., Beloborodova, N. V.

“…High concentration of sepsis-associated aromatic microbial metabolites (AMM) stands as a prognostically unfavorable factor, indicating the progression of…”
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Effect of magnetophoresis and Brownian diffusion on mechanical processes in magnetic fluids: The role of a condensation phase transition by Bashtovoi, V., Reks, A., Kuzhir, P., Zubarev, A., Volkova, O., Moroz, V.

“…In this work, we study theoretically the effect of the mass transfer processes on the volume magnetic force and viscous friction of the magnetic fluid…”
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Controlled lid-opening in Thermomyces lanuginosus lipase– An engineered switch for studying lipase function by Skjold-Jørgensen, Jakob, Vind, Jesper, Moroz, Olga V., Blagova, Elena, Bhatia, Vikram K., Svendsen, Allan, Wilson, Keith S., Bjerrum, Morten J.

“…Here, we present a lipase mutant containing a biochemical switch allowing a controlled opening and closing of the lid independent of the environment. The…”
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Structural and Functional Characterization of Three Novel Fungal Amylases with Enhanced Stability and pH Tolerance by Roth, Christian, Moroz, Olga V, Turkenburg, Johan P, Blagova, Elena, Waterman, Jitka, Ariza, Antonio, Ming, Li, Tianqi, Sun, Andersen, Carsten, Davies, Gideon J, Wilson, Keith S

“…Amylases are probably the best studied glycoside hydrolases and have a huge biotechnological value for industrial processes on starch. Multiple amylases from…”
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Prognostic significance of predictors of early postoperative cognitive disorders in patients after traumatic surgeries (prospective cohort study) by Ermokhina, N. V., Kuzovlev, A. N., Davydov, D.  V., Grechko, A. V., Polyakov, P. A., Ryzhkov, P. V., Serkova, T.  S., Lukyanova, E. A., Belokopytov, D. V., Moroz, V. V.

“…The objective was to determine the prognostic value of predictors of early postoperative cognitive disorders in traumatological patients to assess the…”
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The 85th Anniversary of the V.A. Negovsky Research Institute of General Rehabilitology, Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology (Editorial) by Moroz, V. V., Kuzovlev, A. N., Luginina, E. V., Grechko, A. V.

“…Reanimatology (the science of resuscitation) represents the science of critical illness, terminal and postresuscitation conditions, originated within the walls…”
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Inhibition of Chlamydial Infection by CRISPR/Cas9-SAM Mediated Enhancement of Human Peptidoglycan Recognition Proteins Gene Expression in HeLa Cells by Bobrovsky, P. A., Moroz, V. D., Lavrenova, V. N., Manuvera, V. A., Lazarev, V. N.

“…The global problem of emerging resistance of microorganisms to antibiotics makes the search for new natural substances with antibacterial properties relevant…”
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The 80th Anniversary of the V. A. Negovsky Research Institute of General Reanimatology, Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology by V. V. Moroz, A. V. Grechko

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House cleaning, a part of good housekeeping by Galperin, Michael Y., Moroz, Olga V., Wilson, Keith S., Murzin, Alexey G.

“…Summary Cellular metabolism constantly generates by‐products that are wasteful or even harmful. Such compounds are excreted from the cell or are removed…”
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