Search Results - "Moroni, Dante"

Evidence for Angiotensin II as a Naturally Existing Suppressor for the Guanylyl Cyclase A Receptor and Cyclic GMP Generation by Ma, Xiao, Iyer, Seethalakshmi R, Ma, Xiaoyu, Reginauld, Shawn H, Chen, Yang, Pan, Shuchong, Zheng, Ye, Moroni, Dante G, Yu, Yue, Zhang, Lianwen, Cannone, Valentina, Chen, Horng H, Ferrario, Carlos M, Sangaralingham, S Jeson, Burnett, Jr, John C

“…The natriuretic peptide system (NPS) and renin-angiotensin-aldosterone system (RAAS) function oppositely at multiple levels. While it has long been suspected…”
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Discovery of small molecule guanylyl cyclase B receptor positive allosteric modulators by Ma, Xiao, Peddibhotla, Satyamaheshwar, Zheng, Ye, Pan, Shuchong, Mehta, Alka, Moroni, Dante G, Chen, Qi-Yin, Ma, Xiaoyu, Burnett, Jr, John C, Malany, Siobhan, Sangaralingham, S Jeson

“…Myocardial fibrosis is a pathological hallmark of cardiovascular disease (CVD), and excessive fibrosis can lead to new-onset heart failure and increased…”
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SERUM INSULIN DEGRADING ENZYME IS DETECTABLE IN HUMAN HEART FAILURE AND POSITIVELY CORRELATED WITH INCREASING CIRCULATING B-TYPE NATRIURETIC PEPTIDE by Moroni, Dante, Ma, Xiao, Sangaralingham, Jeson, Burnett, John C.

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Abstract 4140511: Synergistic insulinotropic and lipolytic actions of GLP-1 and a novel miniaturized designer GC-A peptide activator in Beta cells and adipocytes: Potential therapeutic insights for cardiometabolic disease by Zheng, Ye, Pan, Shuchong, Moroni, Dante, Chen, Horng, Sangaralingham, Jeson, Burnett, John

“…Abstract only BACKGROUND: Atrial natriuretic peptide (ANP) and glucagon-like peptide-1 (GLP-1) are endogenous hormones known for roles in cardiovascular…”
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Abstract 4141935: Targeting Tyrosine Kinase Inhibitor-Associated Cardiotoxicity with NPA7: A Novel Dual Activating Peptide by Ma, Xiaoyu, Malsawmzuali, JC, Moroni, Dante, Zheng, Ye, Sangaralingham, Jeson, Burnett, John

“…Abstract only Background: Tyrosine kinase inhibitors (TKIs), such as sunitinib, are highly effective in treating cancers. However, they have severe…”
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CARDIAC APOPTOSIS IS INCREASED IN A RODENT MODEL OF EARLY NON-ALCOHOLIC FATTY LIVER DISEASE by Adel, Fadi, Zheng, Ye, Ameenuddin, Syed, Moroni, Dante, JC, Malsawmzuali, Chen, Horng H.

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Abstract 14638: NPA7: A Novel Designed Bispecific Peptide That Protects Human Cardiomyocytes Against Oxidative Stress Through the GC-A/Mas Receptor-KEAP1-NRF2 Pathway by ma, xiaoyu, Malsawmzuali, JC, Moroni, Dante, Ma, Xiao, Sangaralingham, Jeson, Burnett, John C

“…Abstract only Introduction: Excess cardiomyocyte oxidative stress is a major metabolic abnormality in HTN and its progression to HF. Thus, therapies that…”
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CRRL191: A NOVEL BIOENGINEERED PEPTIDE ACTIVATOR OF THE GUANYLYL CYCLASE A RECEPTOR THAT HAS MORE POTENT AND LONG-LASTING BLOOD PRESSURE LOWERING AND RENAL ENHANCING ACTIONS THAN ATRIAL NATRIURETIC PEPTIDE by Zheng, Ye, Pan, Shuchong, Moroni, Dante, Ma, Xiao, Sangaralingham, Jeson, Burnett, John C.

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Abstract 11943: MCUF-651: A Novel Natriuretic Peptide Receptor A (NPRA) Small Molecule Positive Allosteric Modulator With Blood Pressure Lowering and Renal Enhancing Properties in Experimental Hypertension by Ma, Xiao, Moroni, Dante, Peddibhotla, Satyamaheshwar, Ma, Xiaoyu, Zheng, Ye, Pan, Shuchong, Burnett, John C, Malany, Siobhan, Sangaralingham, Jeson

“…IntroductionHypertension (HTN) represents one of the greatest burdens in human health and is associated with increased morbidity and mortality. Despite the…”
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Abstract 13473: Impaired Atrial Natriuretic Peptide Potency in Human Acute Decompensated Heart Failure and Therapeutic Potential of a Novel Designer Peptide (MANP) Using an Innovative Ex-Vivo Precision Medicine Assay by Reginauld, Shawn H, Zheng, Ye, Moroni, Dante, Ma, Xiao, Chen, Horng, CANNONE, Valentina, Sangaralingham, Jeson, Burnett, John C

“…IntroductionAtrial natriuretic peptide (ANP) is the most potent endogenous activator of the guanylyl cyclase A receptor (GC-A) mediating cardiorenal protective…”
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