Search Results - "Morone, Diego"

ESCRT-III-driven piecemeal micro-ER-phagy remodels the ER during recovery from ER stress by Loi, Marisa, Raimondi, Andrea, Morone, Diego, Molinari, Maurizio

“…The endoplasmic reticulum (ER) produces about 40% of the nucleated cell’s proteome. ER size and content in molecular chaperones increase upon physiologic and…”
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ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies by Low, Jun Siong, Jerak, Josipa, Tortorici, M Alejandra, McCallum, Matthew, Pinto, Dora, Cassotta, Antonino, Foglierini, Mathilde, Mele, Federico, Abdelnabi, Rana, Weynand, Birgit, Noack, Julia, Montiel-Ruiz, Martin, Bianchi, Siro, Benigni, Fabio, Sprugasci, Nicole, Joshi, Anshu, Bowen, John E, Stewart, Cameron, Rexhepaj, Megi, Walls, Alexandra C, Jarrossay, David, Morone, Diego, Paparoditis, Philipp, Garzoni, Christian, Ferrari, Paolo, Ceschi, Alessandro, Neyts, Johan, Purcell, Lisa A, Snell, Gyorgy, Corti, Davide, Lanzavecchia, Antonio, Veesler, David, Sallusto, Federica

“…The coronavirus spike glycoprotein attaches to host receptors and mediates viral fusion. Using a broad screening approach, we isolated seven monoclonal…”
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Maternal Immune Activation Delays Excitatory-to-Inhibitory Gamma-Aminobutyric Acid Switch in Offspring by Corradini, Irene, Focchi, Elisa, Rasile, Marco, Morini, Raffaella, Desiato, Genni, Tomasoni, Romana, Lizier, Michela, Ghirardini, Elsa, Fesce, Riccardo, Morone, Diego, Barajon, Isabella, Antonucci, Flavia, Pozzi, Davide, Matteoli, Michela

“…The association between maternal infection and neurodevelopmental defects in progeny is well established, although the biological mechanisms and the pathogenic…”
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The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell–mediated resistance to metastasis by Mattiola, Irene, Tomay, Federica, De Pizzol, Maria, Silva-Gomes, Rita, Savino, Benedetta, Gulic, Tamara, Doni, Andrea, Lonardi, Silvia, Astrid Boutet, Marie, Nerviani, Alessandra, Carriero, Roberta, Molgora, Martina, Stravalaci, Matteo, Morone, Diego, Shalova, Irina N., Lee, Yunquin, Biswas, Subhra K., Mantovani, Giovanna, Sironi, Marina, Pitzalis, Costantino, Vermi, William, Bottazzi, Barbara, Mantovani, Alberto, Locati, Massimo

“…The plasma membrane tetraspan molecule MS4A4A is selectively expressed by macrophage-lineage cells, but its function is unknown. Here we report that MS4A4A was…”
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Deep learning approach for quantification of organelles and misfolded polypeptide delivery within degradative compartments by Morone, Diego, Marazza, Alessandro, Bergmann, Timothy J., Molinari, Maurizio

“…LysoQuant is a deep learning approach to segmentation and classification of fluorescent images capturing cargo delivery within endolysosomes for clearance. It…”
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TMX4-driven LINC complex disassembly and asymmetric autophagy of the nuclear envelope upon acute ER stress by Kucińska, Marika K., Fedry, Juliette, Galli, Carmela, Morone, Diego, Raimondi, Andrea, Soldà, Tatiana, Förster, Friedrich, Molinari, Maurizio

“…The endoplasmic reticulum (ER) is an organelle of nucleated cells that produces proteins, lipids and oligosaccharides. ER volume and activity are increased…”
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An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode by Doni, Andrea, Musso, Tiziana, Morone, Diego, Bastone, Antonio, Zambelli, Vanessa, Sironi, Marina, Castagnoli, Carlotta, Cambieri, Irene, Stravalaci, Matteo, Pasqualini, Fabio, Laface, Ilaria, Valentino, Sonia, Tartari, Silvia, Ponzetta, Andrea, Maina, Virginia, Barbieri, Silvia S, Tremoli, Elena, Catapano, Alberico L, Norata, Giuseppe D, Bottazzi, Barbara, Garlanda, Cecilia, Mantovani, Alberto

“…Pentraxin 3 (PTX3) is a fluid-phase pattern recognition molecule and a key component of the humoral arm of innate immunity. In four different models of tissue…”
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Author Correction: Evaluation of cell metabolic adaptation in wound and tumour by Fluorescence Lifetime Imaging Microscopy by Morone, Diego, Autilia, Francesca D’, Schorn, Tilo, Erreni, Marco, Doni, Andrea

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Evaluation of cell metabolic adaptation in wound and tumour by Fluorescence Lifetime Imaging Microscopy by Morone, Diego, Autilia, Francesca D’, Schorn, Tilo, Erreni, Marco, Doni, Andrea

“…Acidic pH occurs in acute wounds progressing to healing as consequence of a cell metabolic adaptation in response to injury-induced tissue hypoperfusion. In…”
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The Fractalkine-Receptor Axis Improves Human Colorectal Cancer Prognosis by Limiting Tumor Metastatic Dissemination by Erreni, Marco, Siddiqui, Imran, Marelli, Giulia, Grizzi, Fabio, Bianchi, Paolo, Morone, Diego, Marchesi, Federica, Celesti, Giuseppe, Pesce, Samantha, Doni, Andrea, Rumio, Cristiano, Roncalli, Massimo G, Laghi, Luigi, Mantovani, Alberto, Allavena, Paola

“…Human colorectal cancer (CRC) is a frequent neoplasia in Western countries, and its metastatic progression is a major cause of cancer-related death. In search…”
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Adeno-associated virus-mediated CASQ2 delivery rescues phenotypic alterations in a patient-specific model of recessive catecholaminergic polymorphic ventricular tachycardia by Lodola, Francesco, Morone, Diego, Denegri, Marco, Bongianino, Rossana, Nakahama, Hiroko, Rutigliano, Lucia, Gosetti, Rosanna, Rizzo, Giulia, Vollero, Alessandra, Buonocore, Michelangelo, Napolitano, Carlo, Condorelli, Gianluigi, Priori, Silvia G, Di Pasquale, Elisa

“…Catecholaminergic Polymorphic Ventricular Tachycardia type 2 (CPVT2) is a highly lethal recessive arrhythmogenic disease caused by mutations in the…”
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Tracking unlabeled cancer cells imaged with low resolution in wide migration chambers via U-NET class-1 probability (pseudofluorescence) by Antonello, Paola, Morone, Diego, Pirani, Edisa, Uguccioni, Mariagrazia, Thelen, Marcus, Krause, Rolf, Pizzagalli, Diego Ulisse

“…Cell migration is a pivotal biological process, whose dysregulation is found in many diseases including inflammation and cancer. Advances in microscopy…”
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Prophylactic Activity of Orally Administered FliD-Reactive Monoclonal SIgA Against Campylobacter Infection by Perruzza, Lisa, Jaconi, Stefano, Lombardo, Gloria, Pinna, Debora, Strati, Francesco, Morone, Diego, Seehusen, Frauke, Hu, Yue, Bajoria, Sakshi, Xiong, Jian, Kumru, Ozan Selahattin, Joshi, Sangeeta Bagai, Volkin, David Bernard, Piantanida, Renato, Benigni, Fabio, Grassi, Fabio, Corti, Davide, Pizzuto, Matteo Samuele

“…infection is one of the most common causes of bacterial gastroenteritis worldwide and a major global health threat due to the rapid development of antibiotic…”
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Imaging Cell Interaction in Tracheal Mucosa During Influenza Virus Infection Using Two-photon Intravital Microscopy by Palomino-Segura, Miguel, Virgilio, Tommaso, Morone, Diego, Pizzagalli, Diego U, Gonzalez, Santiago F

“…The analysis of cell-cell or cell-pathogen interaction in vivo is an important tool to understand the dynamics of the immune response to infection. Two-photon…”
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Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes by Rudinskiy, Mikhail, Morone, Diego, Molinari, Maurizio

“…ABSTRACT Lysosomal compartments control the clearance of cell‐own material (autophagy) or of material that cells endocytose from the external environment…”
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ER‐to‐lysosome‐associated degradation of proteasome‐resistant ATZ polymers occurs via receptor‐mediated vesicular transport by Fregno, Ilaria, Fasana, Elisa, Bergmann, Timothy J, Raimondi, Andrea, Loi, Marisa, Soldà, Tatiana, Galli, Carmela, D'Antuono, Rocco, Morone, Diego, Danieli, Alberto, Paganetti, Paolo, van Anken, Eelco, Molinari, Maurizio

“…Maintenance of cellular proteostasis relies on efficient clearance of defective gene products. For misfolded secretory proteins, this involves dislocation from…”
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Humoral innate immunity at the crossroad between microbe and matrix recognition: The role of PTX3 in tissue damage by Doni, Andrea, D'Amico, Giovanna, Morone, Diego, Mantovani, Alberto, Garlanda, Cecilia

“…Innate immunity is involved in regulating inflammatory and tissue repair responses to injury. In particular, humoral innate immunity plays functions related to…”
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CD304 + adipose tissue-derived mesenchymal stem cell abundance in autologous fat grafts highly correlates with improvement of localized pain syndromes by Rezzonico Jost, Tanja, Lozito, Alessia, Mangani, Davide, Raimondi, Andrea, Klinger, Francesco, Morone, Diego, Klinger, Marco, Grassi, Fabio, Vinci, Valeriano

“…Surgery, burns or surgery-free accident are leading causes of scars with altered tissue consistency, a reduced degree of motion and pain. Autologous fat…”
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CANCOL, a Computer-Assisted Annotation Tool to Facilitate Colocalization and Tracking of Immune Cells in Intravital Microscopy by Pizzagalli, Diego Ulisse, Bordini, Joy, Morone, Diego, Pulfer, Alain, Carrillo-Barberà, Pau, Thelen, Benedikt, Ceni, Kevin, Thelen, Marcus, Krause, Rolf, Gonzalez, Santiago Fernandez

“…Two-photon intravital microscopy (2P-IVM) has become a widely used technique to study cell-to-cell interactions in living organisms. Four-dimensional imaging…”
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A Molecular Thermometer for Nanoparticles for Optical Hyperthermia by Freddi, Stefano, Sironi, Laura, D’Antuono, Rocco, Morone, Diego, Donà, Alice, Cabrini, Elisa, D’Alfonso, Laura, Collini, Maddalena, Pallavicini, Piersandro, Baldi, Giovanni, Maggioni, Daniela, Chirico, Giuseppe

“…We developed an all-optical method to measure the temperature on gold (nanorods and nanostars) and magnetite nanoparticles under near-infrared and…”
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