Search Results - "Morodomi, Yosuke"

Clinical Significance of PD-L1 Protein Expression in Surgically Resected Primary Lung Adenocarcinoma by Takada, Kazuki, Okamoto, Tatsuro, Shoji, Fumihiro, Shimokawa, Mototsugu, Akamine, Takaki, Takamori, Shinkichi, Katsura, Masakazu, Suzuki, Yuzo, Fujishita, Takatoshi, Toyokawa, Gouji, Morodomi, Yosuke, Okano, Shinji, Oda, Yoshinao, Maehara, Yoshihiko

“…The clinicopathological features of carcinomas expressing programmed death ligand 1 (PD-L1) and their associations with common driver mutations, such as…”
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Predictive impact for postoperative recurrence using the preoperative prognostic nutritional index in pathological stage I non-small cell lung cancer by Shoji, Fumihiro, Morodomi, Yosuke, Akamine, Takaki, Takamori, Shinkichi, Katsura, Masakazu, Takada, Kazuki, Suzuki, Yuzo, Fujishita, Takatoshi, Okamoto, Tatsuro, Maehara, Yoshihiko

“…Highlights • PNI is calculated based on serum albumin and lymphocyte count in peripheral blood. • We analyzed p-stage I NSCLC patients to investigate effects…”
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Correlation between CXCR4/CXCR7/CXCL12 chemokine axis expression and prognosis in lymph‐node‐positive lung cancer patients by Katsura, Masakazu, Shoji, Fumihiro, Okamoto, Tatsuro, Shimamatsu, Shinichiro, Hirai, Fumihiko, Toyokawa, Gouji, Morodomi, Yosuke, Tagawa, Tetsuzo, Oda, Yoshinao, Maehara, Yoshihiko

“…The CXCR4/CXCR7/CXCL12 chemokine axis plays important roles in the migration of tumor cells during cancer development by modulating site‐specific distant…”
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PD-L1 Is Upregulated by Simultaneous Amplification of the PD-L1 and JAK2 Genes in Non-Small Cell Lung Cancer by Ikeda, Seiichi, Okamoto, Tatsuro, Okano, Shinji, Umemoto, Yuichiro, Tagawa, Tetsuzo, Morodomi, Yosuke, Kohno, Mikihiro, Shimamatsu, Shinichiro, Kitahara, Hirokazu, Suzuki, Yuzo, Fujishita, Takatoshi, Maehara, Yoshihiko

“…The programmed death ligand 1(PD-L1)/programmed cell death protein 1 (PD-1) pathway is one of the most important checkpoint pathways for mediating…”
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Clinical implications of sarcopenia in patients undergoing complete resection for early non-small cell lung cancer by Suzuki, Yuzo, Okamoto, Tatsuro, MD PhD, Fujishita, Takatoshi, Katsura, Masakazu, Akamine, Takaki, Takamori, Shinkichi, Morodomi, Yosuke, Tagawa, Tetsuzo, Shoji, Fumihiro, Maehara, Yoshihiko

“…Highlights • The first report on the relationship between sarcopenia and the outcome of patients with early-stage lung cancer. • Sarcopenia was associated with…”
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Nanomedicines Eradicating Cancer Stem-like Cells in Vivo by pH-Triggered Intracellular Cooperative Action of Loaded Drugs by Kinoh, Hiroaki, Miura, Yutaka, Chida, Tsukasa, Liu, Xueying, Mizuno, Kazue, Fukushima, Shigeto, Morodomi, Yosuke, Nishiyama, Nobuhiro, Cabral, Horacio, Kataoka, Kazunori

“…Nanomedicines capable of control over drug functions have potential for developing resilient therapies, even against tumors harboring recalcitrant cancer stem…”
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The impact of aberrant von Willebrand factor-GPIbα interaction on megakaryopoiesis and platelets in humanized type 2B von Willebrand disease model mouse by Kanaji, Sachiko, Morodomi, Yosuke, Weiler, Hartmut, Zarpellon, Alessandro, Montgomery, Robert R, Ruggeri, Zaverio M, Kanaji, Taisuke

“…Type 2B von Willebrand disease (VWD) is caused by gain-of-function mutations in von Willebrand factor (VWF). Increased VWF affinity for GPIbα results in loss…”
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Tyrosyl-tRNA synthetase stimulates thrombopoietin-independent hematopoiesis accelerating recovery from thrombocytopenia by Kanaji, Taisuke, Vo, My-Nuong, Kanaji, Sachiko, Zarpellon, Alessandro, Shapiro, Ryan, Morodomi, Yosuke, Yuzuriha, Akinori, Eto, Koji, Belani, Rajesh, Do, Minh-Ha, Yang, Xiang-Lei, Ruggeri, Zaverio M., Schimmel, Paul

“…New mechanisms behind blood cell formation continue to be uncovered, with therapeutic approaches for hematological diseases being of great interest. Here we…”
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Nuclear translocation of an aminoacyl-tRNA synthetase may mediate a chronic “integrated stress response” by Jones, Julia A., Wei, Na, Cui, Haissi, Shi, Yi, Fu, Guangsen, Rauniyar, Navin, Shapiro, Ryan, Morodomi, Yosuke, Berenst, Nadine, Dumitru, Calin Dan, Kanaji, Sachiko, Yates, John R., Kanaji, Taisuke, Yang, Xiang-Lei

“…Various stress conditions are signaled through phosphorylation of translation initiation factor eukaryotic initiation factor 2α (eIF2α) to inhibit global…”
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Sca-1 As a Marker of Stress-Induced Thrombopoiesis in Mice by Morodomi, Yosuke, Aiolfi, Roberto, Won, Eric, Kanaji, Sachiko, Schimmel, Paul, Ruggeri, Zaverio M., Kanaji, Taisuke

“…Introduction: It has been shown that megakaryocytes (MKs) can develop from a subset of MK-biased hematopoietic stem cells (HSCs). We also demonstrated that an…”
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782-F Pseudoprogression and subsequent shrinkage of refractory/relapsed pediatric solid tumors induced by GAIA-102: an interim report of the single-agent cohort in Phase I clinical trial by Kawakubo, Naonori, Harada, Yui, Tamaki, Akihiko, Maniwa, Junnosuke, Morodomi, Yosuke, Yonemitsu, Yoshikazu, Tajiri, Tatsuro

“…BackgroundPseudoprogression and subsequent shrinkage of solid tumor foci are typical clinical processes and are seen in approximately 2–8% of cases during…”
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Peritoneal Dissemination Requires an Sp1-Dependent CXCR4/CXCL12 Signaling Axis and Extracellular Matrix-Directed Spheroid Formation by Kasagi, Yuta, Harada, Yui, Morodomi, Yosuke, Iwai, Toshiki, Saito, Satoru, Yoshida, Kumi, Oki, Eiji, Saeki, Hiroshi, Ohgaki, Kippei, Sugiyama, Masahiko, Onimaru, Mitsuho, Maehara, Yoshihiko, Yonemitsu, Yoshikazu

“…Peritonitis carcinomatosa is an advanced and intractable state of gastrointestinal and ovarian cancer, where mechanistic elucidation might enable the…”
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The prognostic impact of the amount of tobacco smoking in non-small cell lung cancer—Differences between adenocarcinoma and squamous cell carcinoma by Okamoto, Tatsuro, Suzuki, Yuzo, Fujishita, Takatoshi, Kitahara, Hirokazu, Shimamatsu, Shinichiro, Kohno, Mikihiro, Morodomi, Yosuke, Kawano, Daigo, Maehara, Yoshihiko

“…Highlights • Never-smokers had a better prognosis than ever-smokers in Ad patients. • Light-smokers had a worse prognosis than heavy smokers in Sq patients. •…”
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Prognostic Significance of Intratumoral Blood Vessel Invasion in Pathologic Stage IA Non-Small Cell Lung Cancer by Shoji, Fumihiro, MD, Haro, Akira, MD, Yoshida, Tsukihisa, MD, Ito, Kensaku, MD, Morodomi, Yosuke, MD, Yano, Tokujiro, MD, Maehara, Yoshihiko, MD

“…Background The 5-year survival rate of pathologic stage IA non-small cell lung cancer (NSCLC) is excellent; however, up to 10% of patients with pathologic…”
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Modified application of Kawamoto’s film method for super‐resolution imaging of megakaryocytes in undecalcified bone marrow by Morodomi, Yosuke, Kanaji, Sachiko, Won, Eric, Kawamoto, Tadafumi, Kanaji, Taisuke

“…Super‐resolution microscopy has enabled high‐resolution imaging of the actin cytoskeleton in megakaryocytes and platelets. These technologies have extended our…”
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Prognostic impact of local treatment against postoperative oligometastases in non-small cell lung cancer by Yano, Tokujiro, Haro, Akira, Yoshida, Tsukihisa, Morodomi, Yosuke, Ito, Kensaku, Shikada, Yasunori, Shoji, Fumihiro, Maruyama, Riichiroh, Maehara, Yoshihiko

“…Objectives In this study, we investigated prognostic factors associated with survival after distantly metastatic recurrence in surgically resected non‐small…”
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Monitoring trifluridine incorporation in the peripheral blood mononuclear cells of colorectal cancer patients under trifluridine/tipiracil medication by Nakanishi, Ryota, Kitao, Hiroyuki, Kiniwa, Mamoru, Morodomi, Yosuke, Iimori, Makoto, Kurashige, Junji, Sugiyama, Masahiko, Nakashima, Yuichiro, Saeki, Hiroshi, Oki, Eiji, Maehara, Yoshihiko

“…Trifluridine/tipiracil (TFTD, TAS-102) is an orally administrated anti-cancer drug with efficacy validated for patients with metastatic colorectal cancer…”
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Clinical Significance of Detecting Somatic Gene Mutations in Surgically Resected Adenosquamous Cell Carcinoma of the Lung in Japanese Patients by Morodomi, Yosuke, Okamoto, Tatsuro, Takenoyama, Mitsuhiro, Takada, Kazuki, Katsura, Masakazu, Suzuki, Yuzo, Fujishita, Takatoshi, Kitahara, Hirokazu, Shimamatsu, Shinichiro, Kohno, Mikihiro, Tagawa, Tetsuzo, Okano, Shinji, Taguchi, Kenichi, Ichinose, Yukito, Maehara, Yoshihiko

“…Background Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) and echinoderm microtubule-associated protein-like 4-anaplastic lymphoma…”
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Clinical Evaluation and Outcomes of Digital Chest Drainage after Lung Resection by Shoji, Fumihiro, Takamori, Shinkichi, Akamine, Takaki, Toyokawa, Gouji, Morodomi, Yosuke, Okamoto, Tatsuro, Maehara, Yoshihiko

“…Background: Analog chest drainage systems (ACS) are generally used to monitor postoperative alveolar air leakage (PAL) after lung resection. An electronic…”
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Prediction of true-negative lymph node metastasis in clinical IA non-small cell lung cancer by measuring standardized uptake values on positron emission tomography by Takenaka, Tomoyoshi, Yano, Tokujiro, Morodomi, Yosuke, Ito, Kensaku, Miura, Naoko, Kawano, Daigo, Shoji, Fumihiro, Baba, Shingo, Abe, Koichiro, Honda, Hiroshi, Maehara, Yoshihiko

“…Purpose We developed a method for predicting true-negative lymph node metastases in clinical IA non-small lung cancer (NSCLC) by the combined evaluation of…”
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