Search Results - "Morlock, Gertrud"

High-performance thin-layer chromatography combined with effect-directed assays and high-resolution mass spectrometry as an emerging hyphenated technology: A tutorial review by Morlock, Gertrud E.

“…Among the analytical advances, hyphenated HPTLC offers great potential for solving pressing questions. It provides straightforward information about effects…”
Get full text

Non-target bioanalytical eight-dimensional hyphenation including bioassay, heart-cut trapping, online desalting, orthogonal separations and mass spectrometry by Schreiner, Tamara, Morlock, Gertrud E.

“…•Robust non-target bioanalytical screening for bioactive compounds was developed.•Eight-dimensional hyphenation: NP-HPTLC–UV/Vis/FLD–EDA–RP-HPLC–PDA–MS•Analyte…”
Get full text

Non-target estrogenic screening of 60 pesticides, six plant protection products, and tomato, grape, and wine samples by planar chromatography combined with the planar yeast estrogen screen bioassay by Mehl, Annabel, Seiferling, Sophia, Morlock, Gertrud E.

“…For non-target residue analysis of xenoestrogens in food, sophisticated chromatographic–mass spectrometric techniques lack in biological effect detection…”
Get full text

All-in-one 2LabsToGo system for analysis of ergot alkaloids in whole rye by Jakob, Kevin, Schwack, Wolfgang, Morlock, Gertrud E.

“…[Display omitted] •All-in-one 2LabsToGo system for atline safety control of rye was introduced.•Sustainable, portable, miniaturized system is proposed for…”
Get full text

Designed genotoxicity profiling detects genotoxic compounds in staple food such as healthy oils by Morlock, Gertrud E., Meyer, Daniel

“…•New genotoxicity profiling was developed to analyze healthy oils for genotoxins.•Healthy oils containing unsaturated fatty acids were shown to be…”
Get full text

Quantitative saccharide release of hydrothermally treated flours by validated salivary/pancreatic on-surface amylolysis (nanoGIT) and high-performance thin-layer chromatography by Müller, Isabel, Morlock, Gertrud E.

Get full text

Non-target bioactive compound profiles of coffee roasts and preparations by Stiefel, Constanze, Lindemann, Bernd, Morlock, Gertrud E.

“…[Display omitted] •Coffee beans roasted differently and coffees prepared differently were studied for effects.•Storage conditions influenced the bioactive…”
Get full text

Concept of a six-fold multiplex planar bioassay to distinguish endocrine agonist, antagonist, cytotoxic and false-positive responses by Meyer, Daniel, Morlock, Gertrud E.

“…To analyze a complex sample for endocrine activity, different tests must be performed to clarify androgen/estrogen agonism, antagonism, cytotoxicity,…”
Get full text

Open-Source-Based 3D Printing of Thin Silica Gel Layers in Planar Chromatography by Fichou, Dimitri, Morlock, Gertrud E

“…On the basis of open-source packages, 3D printing of thin silica gel layers is demonstrated as proof-of-principle for use in planar chromatography. A slurry…”
Get full text

Automated piezoelectric spraying of biological and enzymatic assays for effect-directed analysis of planar chromatograms by Azadniya, Ebrahim, Morlock, Gertrud E.

“…•Set up a cost-effective automated piezoelectric spraying for biological and enzymatic assays.•Bioprofiling of Peganum harmala seed extract via piezoelectric…”
Get full text

Investigation of the estrogenic potential of 15 rosé, white and red wines via effect-directed ten-dimensional hyphenation by Schreiner, Tamara, Morlock, Gertrud E.

“…•Non-target screening of estrogen-like and antiestrogen-like compounds in wine.•NP-HPTLC–UV/Vis/FLD–pYES/pYAES–heart cut–RP-HPLC–DAD–HESI-HRMS/MS.•Differences…”
Get full text

Miniaturized open-source 2LabsToGo screening of lactose-free dairy products and saccharide-containing foods by Morlock, Gertrud E., Koch, Jonathan, Schwack, Wolfgang

“…•Portable small-scale system showed as good performance as state-of-the-art instrumentation.•Cost-efficient open-source all-in-one system helpful for limited…”
Get full text

From Bioprofiling and Characterization to Bioquantification of Natural Antibiotics by Direct Bioautography Linked to High-Resolution Mass Spectrometry: Exemplarily Shown for Salvia miltiorrhiza Root by Jamshidi-Aidji, Maryam, Morlock, Gertrud E

“…Phytochemicals are promising agents in the development of new antibiotics. A streamlined strategy for rapid screening and reliable characterization of…”
Get full text

Miniaturized all-in-one nanoGIT+active system for on-surface metabolization, separation and effect imaging by Morlock, Gertrud E., Drotleff, Lena, Brinkmann, Sabrina

“…Sample components can not only be changed but also activated or inactivated via enzymatic or metabolic reactions. Identifying such activity conversions is the…”
Get full text

HI-HPTLC-UV/Vis/FLD-HESI-HRMS and bioprofiling of steviol glycosides, steviol, and isosteviol in Stevia leaves and foods by Morlock, Gertrud E., Heil, Julia

“…Food products and botanicals on the global market need to be investigated in a more comprehensive way to detect effects, falsifications or adulterations. This…”
Get full text

Orthogonal Hyphenation of Planar and Liquid Chromatography for Mass Spectrometry of Biomarkers out of the Bioassay Matrix (NP-HPTLC-UV/vis/FLD-Bioassay-RP/IEX-HPLC-UV/vis-ESI-MS) by Kirchert, Simone, Morlock, Gertrud E

“…Bioprofiling on the planar chromatogram with in situ biological/enzymatic assays is a powerful bioanalytical screening tool for the nontargeted detection of…”
Get full text

Bioactivity profiles of six baobab fruit pulp powders via planar chromatography hyphenated with effect-directed analysis by Azadniya, Ebrahim, Krawinkel, Michael, Morlock, Gertrud E.

“…Baobab (Adansonia digitata) fruit pulp has a high nutrient content and has been traditionally used for medicinal purposes (e.g., as an anti-inflammatory and…”
Get full text

Fast Equivalency Estimation of Unknown Enzyme Inhibitors in Situ the Effect-Directed Fingerprint, Shown for Bacillus Lipopeptide Extracts by Jamshidi-Aidji, Maryam, Morlock, Gertrud E

“…The hyphenation of high-performance thin-layer chromatography (HPTLC) with enzyme inhibition assays followed by high-resolution mass spectrometry (HRMS)…”
Get full text

Bioprofiling of Salicaceae bud extracts through high-performance thin-layer chromatography hyphenated to biochemical, microbiological and chemical detections by Hage, Salim, Morlock, Gertrud E.

“…•HPTLC analysis of Serbian Salicaceae bud extracts targetedly combined with HRMS•Chemotypical profiling of Serbian poplars by PCA of HPTLC images•Hyphenation…”
Get full text

Effects of the Probiotic Activity of Bacillus subtilis DSM 29784 in Cultures and Feeding Stuff by Kruse, Stefanie, Pierre, Francis, Morlock, Gertrud E

“…The European Union banned the usage of antibiotic growth promoters in animal production. The probiotic microorganism of the genus Bacillus appeared to be an…”
Get full text